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Amgen Inc.

AMGN
Fair ValueBiotech · Commercial
FDA catalysts, PDUFA dates & pipeline intelligence
$413.77
▲ +6.32 · +1.55%

Financials

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Total Assets
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52W LOW $288.0052W HIGH $447.03
Volume
602.37 K
Value Traded
812.26 M
Short % Float
2.61%
+2.12%Week
+5.19%1 Month
+13.26%3 Month
+17.25%6 Month
+33.74%5 Year
+98,606.32%All Time

Cash Data

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Key Stats

Market Cap
223.60 B
EPS (TTM)
16.17
P/E Ratio
25.45
Ent. Value
271.32 B
Total Shares
540.63 M
Float Shares
539.40 M
Insiders
0.23%
Institutions
85.56%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

AMGN Catalyst Timeline

Dated clinical, regulatory and corporate events for Amgen Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Amgen Inc.

2418Total events
12Upcoming
962Tier-1 (high impact)
2010 to 2028Coverage

Upcoming catalysts 2

T2Timing Guidance
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Dazodalibep
T1Confirmatory Trial Result
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LUMAKRASApproved

Event history 50

▲Topline ReadoutDazodalibepClinical Data
Positive topline Phase 3 results for dazodalibep in moderate-to-severe systemic Sjögren's disease
moderate-to-severe systemic Sjögren's diseasesource ↗
▲Primary Endpoint MetDazodalibepClinical Data
OASIZ 301 met primary endpoint of change from baseline in ESSDAI at Week 48
moderate-to-severe systemic Sjögren's diseasesource ↗
▲Label ExpansionIMDELLTRAApprovedFDA Decision
FDA approves reduced monitoring time for first two doses of IMDELLTRA
extensive-stage small cell lung cancer (ES-SCLC)source ↗
▲Primary Endpoint MetIMDELLTRAApprovedClinical Data
IMDELLTRA plus IMFINZI met primary overall survival endpoint in first-line ES-SCLC
first-line extensive stage small cell lung cancersource ↗
▲Secondary Endpoint DataIMDELLTRAApprovedClinical Data
DeLLphi-305 met secondary PFS and ORR endpoints
first-line extensive stage small cell lung cancersource ↗
▲Oral PresentationRepathaApprovedPresentation
Late-breaking presentation of VESALIUS-CV mortality analysis at ESC Congress 2026
high-risk primary preventionsource ↗
▲PublicationRepathaApprovedPresentation
VESALIUS-CV mortality analysis published in Circulation
high-risk primary preventionsource ↗
●Poster PresentationRepathaApprovedPresentation
Poster on Lp(a) testing from CVMOBIUS2 Registry
atherosclerotic cardiovascular diseasesource ↗
▲Oral PresentationRepathaApprovedPresentation
Presentation of total CV events analysis
high-risk primary preventionsource ↗
●Poster PresentationRepathaApprovedPresentation
Poster on lipid management in coronary artery disease
coronary artery diseasesource ↗
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Past FDA Catalysts and PDUFA Decisions

How AMGN actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-12-11Uplizna (inebilizumab-cdon) PDUFA Date ApprovedPDUFA
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

A88 / 100
Pipeline Score
$55.1B
Pipeline Value
$169.9B
Commercial Value
Fair Value
Valuation Signal
74
Drugs Scored
0.8x
rNPV / MCap
Top 1%
Large Pharma
(rank 1 of 658)
Percentile Rank
Amgen Inc. earns an A-grade pipeline score (88/100), with $55.1B risk-adjusted pipeline value, led by Maridebart cafraglutide in Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight (Phase 3).
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q)) Revenue $38.1B x 4.5 = $169.9B
ProductRevenuePrior periodChange
Prolia$3.7B$4.4B-17%
Repatha$3.5B$2.5B+38.3%
EVENITY$2.4B$1.8B+35%
Otezla$2.1B$2.2B-4.9%
TEPEZZA$2.1B$1.8B+13.6%
ENBREL$2.0B$3.0B-31.9%
XGEVA$1.7B$2.2B-20.5%
BLINCYTO$1.7B$1.5B+15.7%
Nplate$1.7B$1.5B+14.2%
TEZSPIRE$1.7B$1.2B+40.9%
KRYSTEXXA$1.4B$1.2B+13.6%
KYPROLIS$1.4B$1.5B-6.7%
Top 12 of 14 product lines shown.
Showing 1 of 74 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Maridebart cafraglutide Small moleculeNCT07226765Obstructive Sleep ApneaPhase 3 ACTIVE NOT_RECRUITING 250Sep 13, 2028
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Clinical Trial Results

Readouts, endpoints and source filings for every AMGN program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
dazodalibep moderate-to-severe Sjögren's diseasePhase 32026-09-22statistically significant and clinically meaningful improvement at Week 48Read MoreAMGEN ANNOUNCES POSITIVE TOPLINE PHASE 3 RESULTS FOR DAZODALIBEP IN MODERATE-TO-SEVERE SYSTEMIC SJÖGREN'S DISEASERead More
Scroll for more · summaries link to the source press release
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Inside Trades

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InsiderSideSharesPriceValueDate
Khosla RachnaOfficer (SVP, Business Development)Option 1,252 7,656 held$162.60 08/13/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
ORBIMED ADVISORS LLC 0.3 % 14.04 M 39.90 K -9.73% ( -4.30 K)
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Shares held by hedge funds each quarter, and who bought or sold.

AMGN Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2027-03-19
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Real-Time Option Chain

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LastVolOILastVolOI
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Calls vs Puts by Expiry

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Competitive positioning

How AMGN ranks across every disease it competes in

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See how AMGN ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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AMGN News

AMGN
Sep 22, 2026
AMGNPhases

AMGEN ANNOUNCES POSITIVE TOPLINE PHASE 3 RESULTS FOR DAZODALIBEP IN MODERATE-TO-SEVERE SYSTEMIC SJÖGREN'S DISEASE

Amgen announced positive topline results from the Phase 3 OASIZ 301 study of dazodalibep for moderate-to-severe Sjögren's disease. The study met its primary endpoint, showing significant improvement in systemic disease activity at Week 48. This marks a potential breakthrough for patients, as there are currently no FDA-approved treatments for this debilitating autoimmune disease.

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AMGN
Sep 14, 2026
AMGNFDA Updates

FDA APPROVES REDUCED MONITORING TIME FOR FIRST TWO DOSES OF IMDELLTRA®

Amgen announced that the FDA has approved a significant reduction in the monitoring time required for the first two doses of IMDELLTRA (tarlatamab-dlle) from 22-24 hours to 6-8 hours. This change aims to enhance patient access to treatment for extensive-stage small cell lung cancer by allowing for less time spent in healthcare settings. Follow-up assessments will still be conducted the day after each of the initial doses.

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AMGN
Sep 9, 2026
AMGNConferences/Events

AMGEN TO PRESENT AT THE MORGAN STANLEY 24TH ANNUAL GLOBAL HEALTHCARE CONFERENCE

Amgen will present at the Morgan Stanley 24th Annual Global Healthcare Conference on September 15, 2026. Key executives, including Jay Bradner and Thomas Dittrich, will discuss the company's developments. The presentation will be available via webcast for the public and investors, with an archive accessible for 90 days post-event.

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AMGN
Sep 8, 2026
AMGNPhases
▼ -10.1%on this newsshared move

IMDELLTRA® IN COMBINATION WITH IMFINZI® DEMONSTRATED LANDMARK IMPROVEMENT IN OVERALL SURVIVAL IN FIRST-LINE EXTENSIVE STAGE SMALL CELL LUNG CANCER

Amgen announced that the Phase 3 DeLLphi-305 study demonstrated a significant improvement in overall survival for IMDELLTRA® in combination with IMFINZI® compared to durvalumab alone. The study also successfully met secondary endpoints, including progression-free survival and objective response rate, marking a notable advancement in treatment for extensive stage small cell lung cancer.

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AMGN
Sep 2, 2026
AMGNConferences/Events

AMGEN TO PRESENT AT THE 2026 WELLS FARGO HEALTHCARE CONFERENCE

Amgen will present at the 2026 Wells Fargo Healthcare Conference on September 10, 2026. Key executives, including the CFO and CMO, will participate in the presentation. The event will be available via a live webcast, allowing media and investors to access the information. The webcast will also be archived for later viewing.

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AMGN
Aug 31, 2026
AMGNPhases

AMGEN'S REPATHA® REDUCES RISK OF DEATH IN PATIENTS AT HIGH RISK FOR A FIRST HEART ATTACK OR STROKE

Amgen announced that Repatha (evolocumab) significantly reduces the risk of death in high-risk adults without prior cardiovascular events, as shown in the Phase 3 VESALIUS-CV trial. The study, which involved over 12,000 patients, demonstrated a 20% reduction in overall mortality. These findings highlight the importance of early and intensive LDL-C lowering in preventing cardiovascular morbidity and mortality.

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AMGN
Aug 27, 2026
AMGNPhases

TEZSPIRE® DEMONSTRATES POSITIVE PHASE 3 RESULTS IN EOSINOPHILIC ESOPHAGITIS ACROSS BOTH CO-PRIMARY AND ALL KEY SECONDARY ENDPOINTS

TEZSPIRE has demonstrated positive Phase 3 results in treating eosinophilic esophagitis, showing statistically significant and clinically meaningful improvements in disease symptoms compared to placebo. The efficacy was maintained through Week 52, highlighting the drug's potential in addressing epithelial-driven inflammatory diseases. These results support the broader application of TEZSPIRE in similar conditions.

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AMGN
Aug 4, 2026
AMGNGeneral

AMGEN REPORTS SECOND QUARTER 2026 FINANCIAL RESULTS

Amgen reported strong financial results for Q2 2026, with total revenues rising 10% to $10.1 billion, driven by significant growth in key products. GAAP EPS increased 65% to $4.37, reflecting higher revenues. However, some products, like Prolia, experienced declines in sales, indicating challenges in certain segments. The company remains optimistic about future growth prospects, particularly with ongoing Phase 3 trials.

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AMGN
Jul 31, 2026
AMGNGeneral

FIRST AMGEN SCHOLARS PROGRAM IN INDIA LAUNCHES AT IIIT HYDERABAD

Amgen has launched its first Scholars Program in India at IIIT Hyderabad, aimed at inspiring future scientific innovators. The program will support 10 undergraduate scholars from various countries, focusing on AI and machine learning applications in healthcare and drug discovery. This initiative reflects Amgen's commitment to advancing science education and fostering collaboration in the region.

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AMGN
Jul 30, 2026
AMGNGeneral

AMGEN ANNOUNCES 2026 THIRD QUARTER DIVIDEND

Amgen announced a dividend of $2.52 per share for the third quarter of 2026, payable on September 11, 2026. This dividend reflects the company's strong financial position and commitment to returning value to shareholders. The announcement highlights Amgen's ongoing innovation in biotechnology and its significant role in the industry.

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AMGN
Jul 30, 2026
AMGNFDA Updates

AVIS FAVORABLE DU CMUH CONCERNANT UNE UTILISATION PLUS LARGE DE REPATHA® D'AMGEN POUR REDUIRE LES RISQUES DE PREMIER INFARCTUS DU MYOCARDE OU D'AVC

Amgen's Repatha (evolocumab) received a favorable opinion from the CMUH for broader use in adults with established atherosclerotic cardiovascular disease or high risk of developing such disease. This recommendation is based on the Phase III VESALIUS-CV trial, which showed significant reduction in major cardiovascular events. If approved by the European Commission, this indication could enhance cardiovascular care in Europe.

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AMGN
Jul 30, 2026
AMGNFDA Updates

LA OPINIÓN FAVORABLE DEL CHMP RESPALDA UN USO MÁS AMPLIO DE REPATHA® DE AMGEN

Amgen's Repatha has received a favorable opinion from the CHMP for broader use in adults at high cardiovascular risk. This recommendation is based on the phase 3 VESALIUS-CV trial, which showed significant reductions in major adverse cardiovascular events. If approved by the European Commission, Repatha could greatly benefit patients who struggle to manage LDL-C levels despite existing therapies.

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AMGN
Jul 30, 2026
AMGNFDA Updates

POSITIVE STELLUNGNAHME DES CHMP UNTERSTÜTZT BREITERE ANWENDUNG VON AMGENS REPATHA® VOR ERSTEM HERZINFARKT ODER SCHLAGANFALL

Amgen announced that the CHMP has issued a positive opinion for Repatha, supporting its use in adults at high risk for cardiovascular events. This recommendation is based on the VESALIUS-CV Phase 3 study, which demonstrated that Repatha significantly lowers the risk of major cardiovascular events. If approved by the European Commission, this could enhance treatment options for patients who struggle to meet LDL-C targets.

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AMGN
Jul 29, 2026
AMGNFDA Updates

POSITIVE CHMP OPINION SUPPORTS BROADER USE OF AMGEN'S REPATHA® BEFORE A FIRST HEART ATTACK OR STROKE

Amgen announced that the CHMP has issued a positive opinion for Repatha, supporting its use in adults at high risk for cardiovascular events. This recommendation is based on the VESALIUS-CV trial, which showed significant reductions in major cardiovascular events. If approved by the European Commission, this could expand treatment options for many patients in Europe.

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AMGN
Jul 28, 2026
AMGNConferences/Events

AMGEN ANNOUNCES WEBCAST OF 2026 SECOND QUARTER FINANCIAL RESULTS

Amgen announced it will report its second quarter 2026 financial results on August 4, 2026, after market close. Following the report, a conference call will be held at 4:30 p.m. ET, featuring CEO Robert A. Bradway and senior management. The call will be broadcast live and archived for future access.

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AMGN
Jun 15, 2026
AMGNGeneral

Harbour BioMed Secures Landmark Victory in U.S. Patent Infringement Case Against Amgen, Reshaping the Global Antibody Patent Landscape

Harbour BioMed achieved a landmark victory in a patent infringement case against Amgen, with a Delaware jury ruling that Amgen willfully infringed Harbour's patent. The jury awarded Harbour $20.2 million in damages, with the possibility of trebling this amount. This ruling affirms the validity of Harbour's innovative antibody technology and sets a precedent in the global antibody patent landscape.

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AMGN
Jun 7, 2026
AMGNConferences/Events

AMGEN PRESENTS NEW DATA ACROSS ITS CARDIOMETABOLIC PORTFOLIO AT AMERICAN DIABETES ASSOCIATION 86TH SCIENTIFIC SESSIONS Amgen (NASDAQ:AMGN) today announced new data at the American Diabetes Association (ADA) 86th Scientific Sessions reinforcing its commitment to...

Amgen presented new data at the American Diabetes Association's 86th Scientific Sessions, showcasing the effectiveness of Repatha in reducing major cardiovascular events among patients with high-risk diabetes. The Phase 3 VESALIUS-CV trial results demonstrated a 29% reduction in these events when Repatha was used alongside LDL-C-lowering therapies. Additionally, real-world evidence was shared, emphasizing the need for adherence to diabetes and obesity treatments to achieve better patient outcomes. Amgen's ongoing research aims to address the interconnected challenges of cardiovascular and metabolic diseases.

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AMGN
Jun 4, 2026
AMGNConferences/Events

AMGEN TO PRESENT AT THE GOLDMAN SACHS 47TH ANNUAL GLOBAL HEALTHCARE CONFERENCE Amgen (NASDAQ:AMGN) will present at the Goldman Sachs 47th Annual Global Healthcare Conference at 9:20 a.m. ET on Tuesday, June 9, 2026. Peter...

Amgen (NASDAQ: AMGN) will present at the Goldman Sachs 47th Annual Global Healthcare Conference on June 9, 2026. Executives Peter Griffith and Murdo Gordon will represent the company, and the presentation will be available via webcast. Amgen is known for its innovative medicines and has a robust pipeline aimed at treating various diseases. The company has a long-standing reputation in the biotechnology industry and has been recognized for its workplace culture.

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AMGN
Jun 3, 2026
AMGNConferences/Events

AMGEN TO PRESENT NEW DATA ACROSS RARE AUTOIMMUNE AND INFLAMMATORY DISEASES AT EULAR 2026 Amgen (NASDAQ:AMGN) today announced the presentation of new data across rare autoimmune and inflammatory diseases at the European Alliance of...

Amgen presented new data on rare autoimmune diseases at the EULAR 2026 Congress, highlighting findings from the Phase 3 MITIGATE trial for UPLIZNA and real-world evidence supporting TAVNEOS. The MITIGATE trial provided insights into immunoglobulin G4-related disease, showcasing UPLIZNA's long-term safety profile and efficacy. Additionally, data from the AQUARIUS analyses confirmed that TAVNEOS helps patients manage ANCA-associated vasculitis while minimizing steroid use. These findings reflect Amgen's ongoing commitment to advancing treatments for challenging medical conditions.

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AMGN
Jun 1, 2026
AMGNFDA Updates

EUROPEAN COMMISSION APPROVES AMGEN'S IMDYLLTRA® FOR THE TREATMENT OF EXTENSIVE-STAGE SMALL CELL LUNG CANCER Amgen (NASDAQ:AMGN) today announced that the European Commission (EC) has granted marketing authorization for IMDYLLTRA® (tarlatamab) as a...

Amgen announced that the European Commission has granted marketing authorization for its novel treatment IMDYLLTRA (tarlatamab) for extensive-stage small cell lung cancer (ES-SCLC). This approval is based on the results of the DeLLphi-304 Phase 3 trial, which indicated a 40% reduction in the risk of death compared to traditional chemotherapy, along with an extension of median overall survival. Despite the promising results, the treatment does have some associated risks, particularly cytokine release syndrome, requiring careful patient monitoring during administration.

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About Amgen Inc.

Thousand Oaks, CA 31,500 employees amgen.com
HeadquartersONE AMGEN CENTER DRIVE, THOUSAND OAKS, CA, 91320
Founded1980
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