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ALIMTA

Phase 2

Carcinoma, Non-Small-Cell Lung | Small molecule | Oncology |Eli Lilly and Company|Last Updated: Jul 20, 2006

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment50

FDA Designations

No designations recorded

Clinical trial landscape

ALIMTA · 6 trials · 6 indications

Phase 2 4Phase 1 2
NCT00051493ALIMTA Plus Carboplatin as Front-Line Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Phase 2 Clinical Trial.Carcinoma, Non-Small-Cell Lung
COMPLETED50 Analytics
NCT00034593A Phase 2 Trial of ALIMTA (Pemetrexed) Plus Gemcitabine in Locally Advanced or Metastatic Transitional Cell Carcinoma of the UrotheliumUrologic Neoplasms
COMPLETED- Analytics
NCT00034619A Phase 2 Trial of ALIMTA (LY231514, Pemetrexed) Plus Oxaliplatin Administered Every 21 Days for First-Line Treatment of Patients With Advanced Colorectal Cancer.Colorectal Cancer
COMPLETED- Analytics
NCT00051506ALIMTA(Pemetrexed)/Cisplatin and ALIMTA(Pemetrexed)/Carboplatin in Extensive Stage Small Cell Lung Cancer.Lung Neoplasms
COMPLETED- Analytics
PHASE2COMPLETED
ALIMTA Plus Carboplatin as Front-Line Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Phase 2 Clinical Trial.
Carcinoma, Non-Small-Cell LungUnlock trial analytics
PHASE2COMPLETED
A Phase 2 Trial of ALIMTA (Pemetrexed) Plus Gemcitabine in Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium
Urologic NeoplasmsUnlock trial analytics
PHASE2COMPLETED
A Phase 2 Trial of ALIMTA (LY231514, Pemetrexed) Plus Oxaliplatin Administered Every 21 Days for First-Line Treatment of Patients With Advanced Colorectal Cancer.
Colorectal CancerUnlock trial analytics
PHASE2COMPLETED
ALIMTA(Pemetrexed)/Cisplatin and ALIMTA(Pemetrexed)/Carboplatin in Extensive Stage Small Cell Lung Cancer.
Lung NeoplasmsUnlock trial analytics

Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
ALIMTADRUG -
CarboplatinDRUG -
gemcitabineDRUG -
OxaliplatinDRUG -
cisplatinDRUG -
folic acidDRUG -
multi-vitaminsDRUG -
irinotecanDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * You have a diagnosis of non-small cell lung cancer. * You have received no prior chemotherapy. * You have at least one measurable lesion. * You have an adequate performance status. * You are at least 18 years of age. Exclusion Criteria: * You have previously received chemoth...

Countries:United StatesFinlandFranceGermany
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Frequently asked questions about ALIMTA

What is ALIMTA used for?

ALIMTA is an investigational oncology drug being studied for use in lung neoplasms, colorectal cancer, non-small-cell lung cancer, metastases, urologic neoplasms, and breast cancer. It is a small molecule developed by Eli Lilly and Company. Clinical trials have explored it in combination with other agents for these cancer types.

Who makes ALIMTA?

ALIMTA is developed by Eli Lilly and Company, a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol LLY. The drug is being investigated for multiple oncology indications including lung cancer, urologic neoplasms, and breast cancer.

What phase is ALIMTA in?

ALIMTA is in Phase 2 clinical development. It is an investigational drug and is not approved by the FDA. Two Phase 2 trials have been completed, along with one Phase 1 trial, all of which are now finished.

What clinical trials is ALIMTA in?

ALIMTA has been studied in several completed clinical trials. NCT00034593 tested ALIMTA plus gemcitabine in transitional cell carcinoma of the urothelium. NCT00051493 evaluated ALIMTA plus carboplatin in non-small-cell lung cancer. NCT00051506 studied ALIMTA with cisplatin or carboplatin in small cell lung cancer. NCT00097383 examined ALIMTA with epirubicin in breast cancer.

Is ALIMTA the same as pemetrexed?

ALIMTA is also known as pemetrexed. Clinical trial titles refer to ALIMTA (Pemetrexed) in combination with other chemotherapy agents. The drug is being investigated for multiple cancer types including non-small-cell lung cancer and breast cancer.