Financials
Cash Data
- Monthly Burn
- Burn Trend
- Dilution Risk
- SEC Filing
Key Stats
Upcoming Catalysts
FDA decisions, readouts and PDUFA dates · scored by probability of approval
BNTX Catalyst Timeline
Dated clinical, regulatory and corporate events for BioNTech SE
Catalyst Timeline
Dated clinical, regulatory & corporate events for BioNTech SE
Upcoming catalysts 2
Event history 50
Past FDA Catalysts and PDUFA Decisions
How BNTX actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2026-10-31 | BNT113 | Phase 3 interim results | Phase 3 |
Drug Pipeline Intelligence
| Product | Revenue | Prior period | Change |
|---|---|---|---|
| COVID-19 vaccine |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BNT323 Antibody-Drug Conjugates (ADCs)NCT06340568 | Endometrial Cancer | Phase 3 | RECRUITING | 480 | Nov 1, 2029 | ||||||
| BNT323 Antibody-Drug Conjugates (ADCs)NCT06018337 | Metastatic Breast Cancer | Phase 3 | ACTIVE NOT_RECRUITING | 541 | Aug 1, 2028 | ||||||
| BNT323 Antibody-Drug Conjugates (ADCs)NCT05150691 | HER2-positive Advanced Solid Tumor | Phase 1/2 | RECRUITING | 796 | Oct 1, 2027 | ||||||
| BNT323 Antibody-Drug Conjugates (ADCs)NCT06827236 | Locally Advanced Breast Cancer | Phase 1/2 | RECRUITING | 380 | Aug 1, 2029 | ||||||
| Pumitamig BiologicsNCT07173751 | Breast Neoplasms | Phase 3 | RECRUITING | 558 | Sep 1, 2030 | ||||||
| Pumitamig BiologicsNCT06419621 | Triple Negative Breast Cancer(TNBC) | Phase 3 | ACTIVE NOT_RECRUITING | 392 | Jul 1, 2028 | ||||||
| Pumitamig BiologicsNCT06449209 | Extensive-stage Small-cell Lung Cancer | Phase 3 | ACTIVE NOT_RECRUITING | 731 | Feb 1, 2028 | ||||||
| Pumitamig BiologicsNCT05879068 | SCLC | Phase 3 | ACTIVE NOT_RECRUITING | 553 | Apr 30, 2026 | ||||||
| Pumitamig BiologicsNCT06841055 | Non-small Cell Lung Cancer | Phase 2/3 | RECRUITING | 1,640 | Oct 1, 2028 | ||||||
| Pumitamig BiologicsNCT05756972 | NSCLC | Phase 2 | ACTIVE NOT_RECRUITING | 64 | Dec 1, 2025 | ||||||
| Pumitamig BiologicsNCT06449222 | Locally Advanced Breast Cancer | Phase 2 | ACTIVE NOT_RECRUITING | 83 | Jun 1, 2029 | ||||||
| Pumitamig BiologicsNCT05918133 | TNBC | Phase 1/2 | ACTIVE NOT_RECRUITING | 42 | Oct 30, 2026 | ||||||
| Pumitamig BiologicsNCT06584071 | HCC | Phase 1/2 | NOT YET_RECRUITING | 140 | Dec 1, 2027 | ||||||
| Pumitamig BiologicsNCT05918445 | Malignant Neoplasm | Phase 1/2 | RECRUITING | 380 | Nov 30, 2025 | ||||||
| Pumitamig BiologicsNCT07133750 | CRC (Colorectal Cancer) | Phase 2 | RECRUITING | 100 | May 1, 2030 | ||||||
| Pumitamig BiologicsNCT07255404 | Pancreatic Ductal Adenocarcinoma (PDAC) | Phase 2 | RECRUITING | 105 | Aug 1, 2028 | ||||||
| Pumitamig BiologicsNCT07297212 | Recurrent Glioblastoma | Phase 2 | RECRUITING | 75 | Jul 1, 2029 | ||||||
| Pumitamig BiologicsNCT05879055 | Neuroendocrine Neoplasm | Phase 2 | ACTIVE NOT_RECRUITING | 31 | Jan 1, 2028 | ||||||
| Gotistobart BiologicsNCT05671510 | Non Small Cell Lung Cancer | Phase 3 | ACTIVE NOT_RECRUITING | 630 | Aug 31, 2028 | ||||||
| BNT168 BiologicsNCT07698600 | HIV -1 Infection | Phase 1 | RECRUITING | 126 | Feb 1, 2028 | ||||||
| BNT324 Small MoleculesNCT07365995 | Metastatic Castration-resistant Prostate Cancer | Phase 3 | RECRUITING | 736 | Feb 1, 2031 | ||||||
| BNT324 Small MoleculesNCT05914116 | Advanced Solid Tumors | Phase 1/2 | RECRUITING | 862 | May 1, 2028 | ||||||
| BNT324 Small MoleculesNCT06953089 | Solid Tumors | Phase 2 | RECRUITING | 750 | Jun 30, 2030 | ||||||
| BNT324 BiologicsNCT06892548 | Advanced Lung Cancer | Phase 1/2 | RECRUITING | 594 | May 1, 2032 | ||||||
| BNT116 BiologicsNCT05142189 | Non-Small Cell Lung Cancer | Phase 1 | RECRUITING | 320 | Nov 1, 2031 |
Clinical Trial Results
Readouts, endpoints and source filings for every BNTX program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| trastuzumab pamirtecan | HR+/HER2-low metastatic breast cancer | Phase 3 | 2026-10-26 | statistically significant, yet modest improvement in progression-free survivalRead More | BioNTech and DualityBio Announce Topline Results of the DYNASTY-Breast02 Global Phase 3 Clinical Trial Evaluating Trastuzumab Pamirtecan in HR+/HER2-low Metastatic Breast CancerRead More |
Inside Trades
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Sahin UgurOfficer (Chief Executive Officer), 10% Owner | Sell | -36,209 | $95.37 | 10/09/2026 |
Hedge Fund 13F Activity
Hedge Funds invested in BNTX
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| Logos Global Management LP | 4.1 % (28.1 %) | 94.45 M | 1.01 M | 407.5% ( 815.00 K) |
Ownership Trends
BNTX Short Interest
Shares sold short, counted twice a month.
Options Data
Option Volume
Option Chain Statistics
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-11-20 | ||||||||||||
Real-Time Option Chain
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
Calls vs Puts by Expiry
Competitive positioning
How BNTX ranks across every disease it competes in
BNTX News
Penn-BioNTech Innovative Therapeutics Seed Fund Announces First Investment
The Penn-BioNTech Innovative Therapeutics Seed Fund has invested in Emvena Therapeutics, which focuses on placenta-targeted mRNA medicines for serious maternal and fetal conditions. Emvena's lead program targets preeclampsia, a significant complication affecting pregnancies. The fund aims to support the translation of University of Pennsylvania research into viable treatments.
Read more →BioNTech Announces Third Quarter 2026 Financial Results and Corporate Update
BioNTech reported third quarter 2026 revenues of €1,289.2 million, a decrease from the previous year. The company raised its full-year revenue guidance to €1.7–1.9 billion, citing strong performance in oncology and COVID-19 vaccine sales. Notable clinical advancements include a global Phase 3 trial for pumitamig in triple-negative breast cancer.
Read more →BioNTech and DualityBio Announce Topline Results of the DYNASTY-Breast02 Global Phase 3 Clinical Trial Evaluating Trastuzumab Pamirtecan in HR+/HER2-low Metastatic Breast Cancer
BioNTech and DualityBio announced that their DYNASTY-Breast02 Phase 3 trial met its primary endpoint, showing a statistically significant improvement in progression-free survival for trastuzumab pamirtecan in HR+/HER2-low metastatic breast cancer. However, a higher incidence of interstitial lung disease was reported, and the overall survival data remains immature. Next steps will be discussed based on these findings.
Read more →BioNTech and Bristol Myers Squibb Report Encouraging Global Phase 2 Data for Pumitamig in Advanced NSCLC After Progression on Immunotherapy Plus Chemotherapy
BioNTech and Bristol Myers Squibb reported promising Phase 2 data for pumitamig in advanced non-small cell lung cancer (NSCLC). The combination with docetaxel achieved a confirmed objective response rate of 36.7% and a median progression-free survival of 6.9 months. This trial addresses a significant unmet need for patients post-immunotherapy and chemotherapy.
Read more →BioNTech Advances Phase 3 Clinical Trial of Pumitamig in Combination with Gilead’s TROP2-Directed ADC Sacituzumab Govitecan in Triple-Negative Breast Cancer
BioNTech announced a collaboration with Gilead to advance the ROSETTA Breast-01 trial, evaluating pumitamig with sacituzumab govitecan for treating PD-L1 low or negative triple-negative breast cancer. This trial aims to replace chemotherapy with an antibody-drug conjugate, reflecting the evolving treatment standards. The combination is expected to improve patient outcomes significantly.
Read more →BioNTech to Report Third Quarter 2026 Financial Results and Corporate Update on November 3, 2026
BioNTech SE will announce its financial results for Q3 2026 on November 3, 2026. The company will also host a conference call and webcast for investors and analysts to discuss these results and provide a corporate update. The event is accessible via registration, and a replay will be available afterward.
Read more →BioNTech to Showcase Oncology Late-Stage Pipeline Progress and Pumitamig Novel-Novel Combination Data at ESMO 2026
BioNTech will present new clinical data from its oncology pipeline at ESMO 2026, including results from the Phase 2 ROSETTA Lung-107 trial evaluating pumitamig in metastatic non-small cell lung cancer. The company will also showcase data on pumitamig's combination with elfetabart drozuntecan in advanced solid tumors. These findings underscore the potential of pumitamig across various tumor types and treatment settings.
Read more →BioNTech Provides Update on Phase 2/3 Clinical Trial for mRNA Cancer Immunotherapy Candidate BNT113 in Metastatic HPV16-positive Head and Neck Cancer
BioNTech's AHEAD-MERIT Phase 2/3 trial for BNT113 in metastatic HPV16-positive head and neck cancer did not achieve its primary endpoint of progression-free survival. However, the trial will proceed to assess overall survival, which could still yield a positive outcome. The mRNA immunotherapy aims to enhance treatment for patients with limited options.
Read more →BioNTech and OncoC4 Present Updated Data Showing Gotistobart Nearly Doubled Median Overall Survival versus Standard-of-Care Chemotherapy in Previously Treated Squamous Non-Small Cell Lung Cancer Patients
BioNTech and OncoC4 reported updated data from the PRESERVE-003 Phase 3 trial, showing that gotistobart significantly improves median overall survival in previously treated squamous non-small cell lung cancer patients. The investigational treatment achieved a median survival of 18.5 months compared to 10.0 months with standard chemotherapy. This data suggests a promising shift in treatment options for patients facing limited alternatives.
Read more →Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine
Pfizer and BioNTech have received FDA approval for their new COVID-19 vaccine formula designed to target the XFG variant. This approval aligns with FDA guidance to ensure the vaccine matches currently circulating variants. Shipping of the vaccine will commence immediately, facilitating rapid access for the upcoming season.
Read more →BioNTech Highlights Late-Stage Lung Cancer Pipeline Momentum and First Global Data for Pumitamig/Elfetabart Drozuntecan Novel-Novel Combination at WCLC 2026
BioNTech SE is showcasing its advancements in lung cancer treatment at the IASLC 2026 World Conference on Lung Cancer. Key highlights include the first clinical data for a novel combination of pumitamig and elfetabart drozuntecan, as well as updated survival data for gotistobart from the PRESERVE-003 Phase 3 trial. The company is committed to addressing unmet medical needs in lung cancer through a diversified clinical pipeline.
Read more →BioNTech Announces Second Quarter 2026 Financial Results and Corporate Update
BioNTech SE reported its second quarter 2026 financial results, highlighting the appointment of Guido Oelkers as CEO and the initiation of six pivotal clinical trials. The company achieved several milestones, including the approval of a new COVID-19 vaccine variant. However, it also faced challenges with a significant net loss and decreased revenues due to lower demand for its vaccines, prompting a revision of its financial guidance for the year.
Read more →BioNTech Announces Appointment of Guido Oelkers to Management Board as Chief Executive Officer
BioNTech has appointed Guido Oelkers as its new CEO, effective by February 1, 2027. Oelkers, who has over 30 years of experience in the biotechnology sector, succeeds Prof. Ugur Sahin. His appointment follows a comprehensive selection process and is expected to enhance BioNTech's growth and innovation in the biopharmaceutical industry.
Read more →European Commission Authorizes Pfizer and BioNTech XFG-adapted COVID-19 Vaccine in the European Union
The European Commission has authorized Pfizer and BioNTech's 2026-2027 COVID-19 vaccine, which targets the XFG variant. This decision follows a recommendation from the EMA's Emergency Task Force, citing strong immune responses against current SARS-CoV-2 lineages. The vaccine is approved for individuals aged six months and older, with manufacturing already underway to meet anticipated demand.
Read more →BioNTech to Report Second Quarter 2026 Financial Results and Corporate Update on August 4, 2026
BioNTech SE will announce its financial results for the second quarter of 2026 on August 4, 2026. A conference call and webcast will be held at 8:00 a.m. ET to discuss these results and provide a corporate update. The event is open to investors and the public, with materials available on the company's website.
Read more →Global Data for BioNTech and Bristol Myers Squibb’s PD-L1xVEGF-A Bispecific Pumitamig Shows Encouraging Efficacy in Patients with Non-Small Cell Lung Cancer in ROSETTA Lung-02 Trial
BioNTech and Bristol Myers Squibb announced promising interim Phase 2 data from the ROSETTA Lung-02 trial, showing high response rates for the bispecific immunomodulator pumitamig in patients with advanced non-small cell lung cancer. The trial demonstrated significant anti-tumor activity across different PD-L1 expression levels, with manageable safety profiles. The companies are advancing further studies to evaluate pumitamig's efficacy.
Read more →BioNTech to Showcase Progress Across Late-Stage Oncology Pipeline at the 2026 ASCO Annual Meeting
BioNTech will present new clinical data from its late-stage oncology pipeline at the 2026 ASCO Annual Meeting. Key highlights include promising results for pumitamig in non-small cell lung cancer and gotistobart in platinum-resistant ovarian cancer. The company is advancing over 25 Phase 2 and Phase 3 trials, focusing on innovative treatment combinations.
Read more →BioNTech SE Shareholders Approve All Agenda Items at the Annual General Meeting 2026
BioNTech SE held its Annual General Meeting where shareholders approved all agenda items, including the expansion of the Supervisory Board. New members with expertise in oncology and clinical development were elected. The company aims to enhance its late-stage oncology pipeline while continuing early research efforts.
Read more →BioNTech Announces New ADS Repurchase Program
BioNTech has announced a new share repurchase program allowing for the repurchase of up to $1 billion in American Depositary Shares until May 6, 2027. This initiative is part of the company's strategy to enhance capital efficiency and support long-term growth. The program will be funded using existing cash resources and is designed to operate within regulatory safe harbors.
Read more →UNAUDITED INTERIM CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Interim Condensed Consolidated Statements of Profit or Loss 1 Interim Condensed Consolidated Statements of Comprehensive Income 2 Interim Condensed Consolidat
BioNTech SE has released its unaudited interim condensed consolidated financial statements for the three months ended March 31, 2026. The company reported a net loss of €531.9 million, a decline from €415.8 million in the same period last year. Revenues also fell significantly, amounting to €118.1 million compared to €182.8 million in the prior year. Additionally, total assets decreased from €21,988.6 million to €21,074.1 million over the same time frame.
Read more →