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Eli Lilly and Company

LLYFDA catalysts, PDUFA dates & pipeline intelligence
$1,279.14
▲ +9.43 · +0.74%

Financials

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Total Assets
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Quarterly Cash
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52W LOW $809.6352W HIGH $1,321.21
Volume
2.11 M
Value Traded
3.68 B
Short % Float
0.83%
Days to Cover
2.9
-0.35%Week
+7.96%1 Month
+4.79%3 Month
+46.35%6 Month
+432.5%5 Year
+37,819.33%All Time

Cash Data

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  • SEC Filing

Key Stats

Market Cap
1204.13 B
EPS (TTM)
29.97
P/E Ratio
42.69
Ent. Value
1243.04 B
Total Shares
940.94 M
Float Shares
848.41 M
Insiders
9.87%
Institutions
76.46%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
BLA Submission
retatrutide
obesity, knee osteoarthritis pain, obstructive sleep apnea
BLAPeptidesEndocrine System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

LLY Catalyst Timeline

Dated clinical, regulatory and corporate events for Eli Lilly and Company

Catalyst Timeline

Dated clinical, regulatory & corporate events for Eli Lilly and Company

2713Total events
63Upcoming
1129Tier-1 (high impact)
2011 to 2040Coverage

Upcoming catalysts 2

T2Product Launch
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OnswikApproved
T3Enrollment Milestone
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BaricitinibApproved

Event history 50

▲Oral PresentationOlomorasibPresentation
Rapid oral presentation of olomorasib plus chemoimmunotherapy first-line NSCLC data at ESMO 2026
first-line advanced KRAS G12C-mutant NSCLCsource ↗
▲Poster PresentationOlomorasibPresentation
Poster presentation of olomorasib plus pembrolizumab first-line NSCLC data at ESMO 2026
first-line KRAS G12C-mutant non-small cell lung cancersource ↗
▲Oral Presentationsofetabart mipitecanPresentation
Phase 1 Sofe-M plus bevacizumab data presented orally at ESMO 2026
platinum-sensitive ovarian cancersource ↗
▲Topline Readoutsofetabart mipitecanClinical Data
Phase 1 Sofe-M plus bevacizumab shows 79.3% cORR and 100% DCR in PSOC
platinum-sensitive ovarian cancersource ↗
▲Manufacturing MilestoneCMC / Inspection
Lilly breaks ground on $5B Richmond, Virginia manufacturing facility for ADCs and large-molecule medicines
▲Primary Endpoint MetMirikizumabApprovedClinical Data
Omvoh meets primary endpoint of clinical remission at Week 52 in pediatric UC (SHINE-2)
pediatric ulcerative colitissource ↗
●Safety Data UpdateMirikizumabApprovedClinical Data
SHINE-2 safety profile through Week 52 consistent with adults, no new signals
pediatric ulcerative colitissource ↗
▲Late-BreakerMirikizumabApprovedPresentation
SHINE-2 one-year results presented as late-breaking oral presentation at UEG Week 2026
pediatric ulcerative colitissource ↗
▲Full ResultsMirikizumabApprovedClinical Data
One-year Phase 3 SHINE-2 results in pediatric UC reported
pediatric ulcerative colitissource ↗
▲Additional DataMirikizumabApprovedClinical Data
Post hoc analysis of corticosteroid-free deep remission at one year in VIVID-1
Crohn's diseasesource ↗
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Past FDA Catalysts and PDUFA Decisions

How LLY actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-26selpercatinib (Retevmo) Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
126
Drugs Scored
rNPV / MCap
Top Drug
Top 1%
Large Pharma
(rank 1 of 657)
Percentile Rank
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q))
ProductRevenuePrior periodChange
Mounjaro
Zepbound
Verzenio
Trulicity
Jardiance
Taltz
Showing 92 of 908 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Orforglipron Small moleculeNCT07153471OsteoarthritisPhase 3 ACTIVE NOT_RECRUITING 800May 1, 2028
Baricitinib Small moleculeNCT04088396Systemic Juvenile Idiopathic ArthritisPhase 3 ACTIVE NOT_RECRUITING 58Oct 1, 2026
Orforglipron Small moleculeMarketedNCT06972459ObesityPhase 3 ACTIVE NOT_RECRUITING 8,741Aug 1, 2027
Retatrutide Small moleculeNCT06859268ObesityPhase 3 ACTIVE NOT_RECRUITING 7,605Apr 1, 2028
Retatrutide Small moleculeNCT06260722Type 2 Diabetes MellitusPhase 3 ACTIVE NOT_RECRUITING 1,330Feb 1, 2027
Retatrutide Small moleculeNCT06297603Diabetes Type 2Phase 3 ACTIVE NOT_RECRUITING 2,009Nov 1, 2026
Orforglipron Small moleculeNCT07202884Urinary Incontinence,StressPhase 3 RECRUITING 1,000Mar 1, 2028
Baricitinib Small moleculeNCT07222137Diabetes Mellitus, Type 1Phase 3 RECRUITING 450Jul 1, 2031
Orforglipron Small moleculeNCT07613307Diabetes Mellitus, Type 2Phase 3 RECRUITING 300May 1, 2027
Orforglipron Small moleculeNCT06952530HypertensionPhase 3 ACTIVE NOT_RECRUITING 1,948Sep 1, 2027
Orforglipron Small moleculeNCT07223593Peripheral Arterial DiseasePhase 3 RECRUITING 1,205Jun 1, 2028
Baricitinib Small moleculeNCT04088409UveitisPhase 3 ACTIVE NOT_RECRUITING 30Jul 1, 2028
Orforglipron Small moleculeNCT07241390Atherosclerosis Cardiovascular DiseasePhase 3 RECRUITING 7,140Aug 1, 2031
Orforglipron Small moleculeMarketedNCT07794579OverweightPhase 3 RECRUITING 2,001Sep 1, 2030
Retatrutide Small moleculeNCT06383390Atherosclerotic Cardiovascular Disease (ASCVD)Phase 3 ACTIVE NOT_RECRUITING 10,000Feb 1, 2029
Retatrutide Small moleculeNCT06982859Diabetes MellitusPhase 1 ACTIVE NOT_RECRUITING 95Jan 1, 2027
Olomorasib Small moleculeNCT06890598Carcinoma, Non-Small-Cell LungPhase 3 RECRUITING 700Feb 1, 2032
LY3537982 Small moleculeNCT04956640Carcinoma, Non-Small-Cell LungPhase 3 ACTIVE NOT_RECRUITING 1,804Apr 1, 2027
Olomorasib Small moleculeNCT07814417Colorectal NeoplasmsPhase 2 NOT YET_RECRUITING 50Nov 1, 2028
LY3938577 Small moleculeNCT07215312Type 2 Diabetes MellitusPhase 2 ACTIVE NOT_RECRUITING 166Dec 1, 2026
Lepodisiran RNA therapyNCT06292013Atherosclerotic Cardiovascular Disease (ASCVD)Phase 3 ACTIVE NOT_RECRUITING 17,300Mar 1, 2029
Lepodisiran RNA therapyNCT07613294AtherosclerosisPhase 3 RECRUITING 252Dec 1, 2029
Eloralintide Small moleculeNCT07369011Sleep Apnea, ObstructivePhase 3 RECRUITING 800Apr 1, 2028
Eloralintide Small moleculeNCT07353931OsteoarthritisPhase 3 RECRUITING 900May 1, 2028
LY3841136 Small moleculeNCT07401862Hepatic InsufficiencyPhase 1 RECRUITING 36Mar 1, 2027
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every LLY program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
olomorasib
Breakthrough
KRAS G12C-mutant non-small cell lung cancerPhase 1/22026-10-25median progression free survival: not reached after nearly 21 months; overall response rate: 62%; median duration of response: 14.5 monthsRead MoreNew data on Lilly's investigational treatment olomorasib at ESMO 2026 show durable first-line activity in KRAS G12C-mutant non-small cell lung cancerRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Jonsson PatrikOfficer (EVP & President, LLY Int'l)Sell -6,500 54,146.62 held$1,175.10 08/17/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
ORBIMED ADVISORS LLC 5.7 % (32.6 %) 309.33 M 257.90 K 8.91% ( 21.10 K)
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Shares held by hedge funds each quarter, and who bought or sold.

LLY Institutional Ownership Trends

LLY Short Interest

Shares sold short, counted twice a month.

0.83%
Short % of Float
of tradable shares sold short
7.0M
Shares Sold Short
-6.4% vs prior count
2.9 Moderate
Days to Cover
trading days of normal volume to buy every short share back
2.4M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-30
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How LLY ranks across every disease it competes in

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LLY News

LLY
Oct 26, 2026
LLYGeneral
▲ +0.7%today

Lilly declares fourth-quarter 2026 dividend

Eli Lilly and Company announced a fourth-quarter 2026 dividend of $1.73 per share. This dividend will be paid on December 10, 2026, to shareholders recorded by November 13, 2026. The announcement highlights Lilly's commitment to returning value to shareholders amidst ongoing advancements in healthcare.

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LLY
Oct 25, 2026
LLYPhases
▲ +0.7%today

New data on Lilly's investigational treatment olomorasib at ESMO 2026 show durable first-line activity in KRAS G12C-mutant non-small cell lung cancer

Eli Lilly presented promising data on olomorasib at ESMO 2026, showing durable first-line activity in KRAS G12C-mutant non-small cell lung cancer (NSCLC). The Phase 1/2 LOXO-RAS-20001 trial indicated median progression-free survival had not been reached after nearly 21 months. The ongoing Phase 3 SUNRAY-01 trial is expected to provide further insights in 2027.

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LLY
Oct 24, 2026
LLYPhases
▲ +0.7%today

Lilly presents first clinical data in platinum-sensitive ovarian cancer for its investigational, next-generation, FRα-targeting ADC at ESMO 2026

Eli Lilly presented Phase 1 data for its investigational ADC, Sofetabart mipitecan (Sofe-M), at ESMO 2026. The combination with bevacizumab showed a 79% confirmed objective response rate and a 100% disease control rate in patients with platinum-sensitive ovarian cancer. The study indicates potential efficacy even in patients previously treated with PARP inhibitors.

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LLY
Oct 22, 2026
LLYGeneral

Lilly breaks ground in Richmond to expand American manufacturing of next-generation cancer medicines, advancing its build-out of 10 new U.S. sites since 2020

Eli Lilly has begun construction on a $5 billion manufacturing facility in Richmond, Virginia, which will create 650 high-wage jobs. This site will be the first to produce both active pharmaceutical ingredients and finished medicines in a fully integrated facility. The investment is part of Lilly's broader initiative to expand U.S. manufacturing capabilities.

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LLY
Oct 19, 2026
LLYPhases

Lilly's Omvoh (mirikizumab-mrkz) meets primary endpoint of clinical remission and is the first IL-23p19 inhibitor to report one-year Phase 3 results in pediatric ulcerative colitis

Eli Lilly announced positive one-year results from the Phase 3 SHINE-2 study of Omvoh (mirikizumab-mrkz) in pediatric patients with moderately to severely active ulcerative colitis. The study found that 81% of patients responded to treatment, with 50% achieving clinical remission at one year. Lilly plans to submit these findings to regulators for potential label expansion to include pediatric patients.

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LLY
Oct 18, 2026
LLYConferences/Events

Lilly to showcase advances across its oncology pipeline at the 2026 European Society for Medical Oncology (ESMO) Congress

Eli Lilly and Company will showcase new data from its oncology pipeline at the 2026 ESMO Congress. Key presentations include Phase 1 data for sofetabart mipitecan in platinum-sensitive ovarian cancer, updated findings for olomorasib in KRAS G12C-mutant lung cancer, and results for Retevmo in RET-mutant medullary thyroid cancer. The data highlight Lilly's commitment to advancing cancer care.

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LLY
Oct 15, 2026
LLYConferences/Events

Lilly confirms date and conference call for third-quarter 2026 financial results announcement

Eli Lilly and Company will announce its third-quarter 2026 financial results on October 29, 2026. A conference call will follow at 10 a.m. Eastern time, providing details on the company's financial performance. The call will be accessible via a live webcast, with a replay available afterward.

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LLY
Oct 15, 2026
LLYPhases

New composite outcomes data show patients treated with Lilly's Omvoh (mirikizumab-mrkz) achieved comprehensive corticosteroid-free disease control in ulcerative colitis and corticosteroid-free deep remission in Crohn's disease at one year

Eli Lilly's Omvoh (mirikizumab-mrkz) has shown promising results in treating ulcerative colitis and Crohn's disease. In clinical trials, a significant percentage of patients achieved comprehensive disease control and corticosteroid-free deep remission, even those with previous treatment failures. These findings highlight a shift towards more holistic treatment goals in inflammatory bowel disease management.

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LLY
Oct 9, 2026
LLYPhases

New Phase 3b data on Lilly's Taltz (ixekizumab) and Zepbound (tirzepatide) advance understanding of the interconnected immune and metabolic biology in adults with psoriasis and obesity

Eli Lilly presented new data from the TOGETHER-PsO Phase 3b trial, showing that the combination of Taltz and Zepbound leads to broader biomarker changes compared to Taltz alone in patients with psoriasis and obesity. The findings suggest a significant immunometabolic relationship, supporting a more integrated treatment approach. The study highlights the potential for improved patient outcomes in managing both conditions.

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LLY
Oct 5, 2026
LLYConferences/Events

Lilly to present new data across its dermatology portfolio with 21 presentations at Fall Clinical 2026, in pursuit of advancing care for chronic skin conditions

Eli Lilly will present 21 new data presentations at the Fall Clinical Dermatology Conference 2026, focusing on its dermatology portfolio. Key highlights include findings on EBGLYSS for atopic dermatitis, Taltz and Zepbound for psoriasis and obesity, and long-term outcomes for Olumiant in alopecia areata. The data aims to enhance understanding and treatment of chronic skin conditions.

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LLY
Oct 2, 2026
LLYFDA Updates

Lilly's Jaypirca (pirtobrutinib), the first-and-only approved non-covalent BTK inhibitor, receives expanded indication from U.S. FDA for certain patients with previously untreated CLL/SLL

Eli Lilly's Jaypirca (pirtobrutinib) has received FDA approval for an expanded indication, allowing its use as a first-line treatment for adult patients with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) without known 17p deletion. This decision is based on the positive results from the BRUIN CLL-313 clinical trial, which demonstrated significant improvements in progression-free survival compared to standard chemoimmunotherapy. The approval highlights Jaypirca's role in the treatment continuum for CLL/SLL.

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LLY
Oct 1, 2026
LLYPhases

Lilly's oral GLP-1, Foundayo (orforglipron), was associated with significant reductions in predicted long-term risk of type 2 diabetes and cardiovascular disease

Eli Lilly announced that its oral GLP-1 medication, Foundayo, demonstrated significant reductions in the predicted long-term risks of type 2 diabetes and cardiovascular disease in adults with obesity or overweight. The findings, derived from post-hoc analyses of the ATTAIN-1 trial, suggest that Foundayo could be a valuable treatment option, potentially reducing healthcare costs linked to obesity. The results were published in Diabetes, Obesity and Metabolism.

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LLY
Sep 30, 2026
LLYPhases

Lilly's oral GLP-1, Foundayo (orforglipron), demonstrated cardiovascular safety alongside sustained A1C reduction and weight loss in its largest and longest type 2 diabetes study

Eli Lilly's Phase 3 ACHIEVE-4 trial results for Foundayo (orforglipron) showed it met non-inferiority criteria for major adverse cardiovascular events compared to insulin glargine. The study revealed significant reductions in cardiovascular death and all-cause mortality, alongside improvements in A1C and weight. Foundayo's convenient once-daily dosing may enhance patient adherence.

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LLY
Sep 30, 2026
LLYPhases

New Phase 3b data show Lilly's EBGLYSS (lebrikizumab-lbkz) delivered significant and rapid improvements in skin clearance, itch, pain, and patient satisfaction in people with moderate-to-severe hand and foot atopic dermatitis

Eli Lilly's EBGLYSS (lebrikizumab-lbkz) has shown promising results in a Phase 3b study for treating moderate-to-severe hand and foot atopic dermatitis. The study reported that over 53% of patients achieved clear or almost clear skin by Week 16, with significant improvements in itch and pain relief. Additionally, nearly 80% of patients expressed satisfaction with their treatment outcomes. These findings will be presented at the EADV Congress.

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LLY
Sep 30, 2026
LLYPhases

Lilly's EloraTZP (combination of eloralintide and tirzepatide) delivered greater weight loss and A1C reduction vs. tirzepatide 15 mg in adults with obesity and type 2 diabetes

Eli Lilly announced positive results from a Phase 2b trial of EloraTZP, a combination of eloralintide and tirzepatide, showing greater weight loss and A1C reduction compared to tirzepatide alone. Participants lost an average of 54.1 lbs and lowered A1C by 2.9% over 48 weeks. Lilly plans to initiate Phase 3 trials by the end of 2026.

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LLY
Sep 29, 2026
LLYPhases

Lilly's triple agonist, retatrutide, delivered substantial weight loss and A1C reduction, underscoring its potential promise for people with obesity and type 2 diabetes

Eli Lilly's TRIUMPH-2 trial results show that retatrutide, a triple hormone receptor agonist, led to significant weight loss and A1C reductions in adults with obesity and type 2 diabetes. Over 80 weeks, participants lost an average of 49.6 lbs, with many no longer classified as obese. The drug also demonstrated improvements in cardiovascular risk factors. Lilly plans to submit a Biologics License Application in early 2027.

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LLY
Sep 29, 2026
LLYPhases

Lilly's Zepbound (tirzepatide 10 mg and 15 mg) was associated with more weight loss than Wegovy HD (semaglutide injection 7.2 mg) in a new indirect treatment comparison

Eli Lilly's Zepbound (tirzepatide) 10 mg and 15 mg demonstrated greater weight loss compared to Wegovy HD (semaglutide injection 7.2 mg) in a recent analysis. The study, presented at the EASD Annual Meeting, showed that participants on Zepbound 15 mg had over three times the odds of achieving at least a 20% body weight reduction. While the results are promising, some differences in weight loss did not reach statistical significance.

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LLY
Sep 29, 2026
LLYPhases

Lilly's Foundayo (orforglipron) 17.2 mg showed greater weight loss and A1C reduction than oral semaglutide 25 mg among adults with type 2 diabetes in a new indirect treatment comparison

Eli Lilly announced that Foundayo (orforglipron) 17.2 mg resulted in greater weight loss and A1C reduction compared to oral semaglutide 25 mg in adults with type 2 diabetes. The findings, presented at the EASD Annual Meeting, are based on an indirect comparison using data from the ACHIEVE-3 and PIONEER PLUS studies. This analysis highlights Foundayo's potential as an effective treatment option for managing type 2 diabetes.

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LLY
Sep 28, 2026
LLYGeneral

Lilly launches the Lilly Change the Course Commitment, aiming to address treatment gaps in diabetes and obesity in LMICs

Eli Lilly has launched the Lilly Change the Course Commitment, aiming to provide equal access to its diabetes and obesity medicines in low- and middle-income countries (LMICs) by 2040. The initiative focuses on registering innovative treatments and strengthening health systems to address significant access gaps. This commitment builds on the success of the previous Lilly 30x30 initiative, which exceeded its target of helping 30 million people by 2025.

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LLY
Sep 25, 2026
LLYFDA Updates

FDA approves Lilly's Olumiant (baricitinib) for pediatric patients 12 years of age and older with severe alopecia areata

The FDA has approved Eli Lilly's Olumiant (baricitinib) for pediatric patients aged 12 and older with severe alopecia areata. This decision is based on data from the BRAVE-AA-PEDS study, which demonstrated significant scalp hair regrowth and improved eyebrow and eyelash coverage. The approval provides a much-needed treatment option for adolescents facing the challenges of this chronic condition.

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About Eli Lilly and Company

Indianapolis, IN 50,000 employees lilly.com
HeadquartersLILLY CORPORATE CTR, INDIANAPOLIS, IN, 46285
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