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Darinaparson

Phase 2

Multiple Myeloma | Small molecule | Oncology |Alaunos Therapeutics, Inc.|Last Updated: Sep 29, 2026

Development status

Highest phase Phase 2
Registered trials 1 across 1 sponsor since Jan 2007

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment17

FDA Designations

No designations recorded

Clinical trial landscape

Darinaparson · 1 trial · 1 indication

Phase 2 1
NCT00423644A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001bMultiple Myeloma
COMPLETED17 Analytics
PHASE2COMPLETED
A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001b
Multiple MyelomaUnlock trial analytics

Study Endpoints

Primary Endpoints

Response Rate
6 months

Secondary Endpoints

Survival (overall and progression free)
6 months
toxicities
6 months
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Single ArmEXPERIMENTAL -

Interventions

NameTypeDescription
DarinaparsonDRUG420 mg/m2 of Darinaparsin given twice weekly for three weeks, followed by one week of rest for up to six months
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites8

Inclusion Criteria 1. Subjects with a confirmed diagnosis of active multiple myeloma with measurable protein criteria present to evaluate response. Measurable disease is defined as having at least one of the following criteria within 28 days prior to registration: 1. Serum M-protein level \> 0....

Countries:United States
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