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Moderna, Inc.

MRNAFDA catalysts, PDUFA dates & pipeline intelligence
$221.72
▼ -2 · -0.9%

Financials

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Total Assets
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52W LOW $22.2852W HIGH $254.48
Volume
9.02 M
Value Traded
371.75 M
Short % Float
8.93%
Days to Cover
1.8
+10.8%Week
+15.14%1 Month
+304.45%3 Month
+388.69%6 Month
-72.25%5 Year
+113.09%All Time

Cash Data

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  • Monthly Burn
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  • SEC Filing

Key Stats

Market Cap
88.52 B
EPS (TTM)
-7.89
P/E Ratio
-
Ent. Value
82.20 B
Total Shares
399.24 M
Float Shares
365.20 M
Insiders
8.52%
Institutions
80.29%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 interim results
Norovirus Vaccine (mRNA-1403)
Norovirus
Phase 3VaccinesInfectious Diseases
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

MRNA Catalyst Timeline

Dated clinical, regulatory and corporate events for Moderna, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Moderna, Inc.

451Total events
10Upcoming
168Tier-1 (high impact)
2021 to 2027Coverage

Upcoming catalysts 2

T1FDA Approval
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mRNA-1010Approved
T1Late-Breaker
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intismeran autogene

Event history 50

◆Equity OfferingCorporate
Closing of convertible notes offering expected
◆Debt Royalty FinancingCorporate
Closing of $2.6 billion Convertible Senior Notes offering
▼Equity OfferingCorporate
Pricing of upsized $2.6 billion convertible senior notes offering
▼Debt Royalty FinancingCorporate
Pricing of $2.6 billion Convertible Senior Notes due 2032
▲Primary Endpoint Metintismeran autogeneClinical Data
INTerpath-001 met primary endpoint of recurrence-free survival
completely resected stage IIB–IV melanomasource ↗
▲Topline Readoutintismeran autogeneClinical Data
Positive topline results from Phase 3 INTerpath-001 with intismeran autogene plus KEYTRUDA
resected stage IIB-IV melanomasource ↗
▲FDA ApprovalmFLUSIVAApprovedFDA Decision
mFLUSIVA approved by FDA for seasonal influenza
seasonal influenzasource ↗
◆R&D DayPresentation
ASCO Investor Event
▲FDA ApprovalmNEXSPIKEApprovedFDA Decision
EU approval of mNEXSPIKE
COVID-19source ↗
▲FDA ApprovalmCOMBRIAXApprovedFDA Decision
EU approval of mCOMBRIAX (flu + COVID combination vaccine)
Flu + COVID combinationsource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How MRNA actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-23intismeran autogene (intismeran; V940/mRNA-4157) + KEYTRUDA (pembrolizumab) Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
30
Drugs Scored
rNPV / MCap
Top Drug
Top 2%
Large Pharma
(rank 14 of 657)
Percentile Rank
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q))
ProductRevenuePrior periodChange
COVID-19
RSV
Showing 44 of 55 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
mRNA-1403 VaccineNCT06592794Acute GastroenteritisPhase 3 ACTIVE NOT_RECRUITING 37,864Feb 15, 2027
mRNA-1018-H5 VaccineNCT07496450InfluenzaPhase 3 ACTIVE NOT_RECRUITING 4,050Jan 28, 2027
mRNA-1195 VaccineNCT06735248Multiple SclerosisPhase 2 RECRUITING 180Jan 8, 2029
mRNA-1195.1 VaccineNCT05831111Epstein-Barr Virus InfectionPhase 1 ACTIVE NOT_RECRUITING 482Oct 13, 2026
mRNA-4157 RNA therapyNCT03897881MelanomaPhase 2 ACTIVE NOT_RECRUITING 267Nov 21, 2032
mRNA-4157 RNA therapyNCT03313778Solid TumorsPhase 1 ACTIVE NOT_RECRUITING 161Nov 21, 2027
mRNA-2808 RNA therapyNCT07116616Relapsed or Refractory Multiple MyelomaPhase 1 RECRUITING 190Jun 17, 2032
mRNA-1365 VaccineNCT07764237Respiratory Syncytial Virus (RSV)Phase 1 RECRUITING 375Jul 20, 2027
mRNA-1469 VaccineNCT07737717Ebola-Bundibugyo Virus Disease (Ebola-BDBV)Phase 1 ACTIVE NOT_RECRUITING 84Sep 30, 2027
mRNA-4359 RNA therapyNCT05533697Advanced Solid TumorsPhase 1 RECRUITING 361Feb 18, 2032
mRNA-1982 VaccineNCT07561294Lyme DiseasePhase 2 ACTIVE NOT_RECRUITING 366Nov 9, 2028
mRNA-4106 RNA therapyNCT06880549Advanced Solid TumorsPhase 1 RECRUITING 42Aug 3, 2027
mRNA-1189 VaccineNCT07478952Epstein-Barr VirusPhase 1 RECRUITING 120May 15, 2027
mRNA-1189 VaccineNCT05164094Epstein-Barr Virus InfectionPhase 1 ACTIVE NOT_RECRUITING 867Aug 18, 2027
mRNA-1647 VaccineNCT05683457Cytomegalovirus InfectionPhase 2 ACTIVE NOT_RECRUITING 724Mar 6, 2027
mRNA-3745 RNA therapyNCT05095727Glycogen Storage DiseasePhase 1 ACTIVE NOT_RECRUITING 15Nov 30, 2026
mRNA-3705 RNA therapyNCT05295433Methylmalonic AcidemiaPhase 1 RECRUITING 56Apr 2, 2034
mRNA-3927 RNA therapyNCT05130437Propionic AcidemiaPhase 1 RECRUITING 127Dec 4, 2031
mRNA-1345 VaccineMarketedNCT05743881Respiratory Syncytial VirusPhase 3 ACTIVE NOT_RECRUITING 45,237Aug 31, 2029
mRNA-1083 VaccineCompletedNCT06694389COVID-19Phase 3 COMPLETED 2,457Nov 17, 2025
mRNA-1083 VaccineCompletedNCT06097273SARS-CoV-2Phase 3 COMPLETED 8,061May 28, 2024
mRNA-1083 VaccineCompletedNCT06508320InfluenzaPhase 2 COMPLETED 931Sep 25, 2025
mRNA-1083 Composition 1 Dose A Lot A VaccineCompletedNCT06864143InfluenzaPhase 2 COMPLETED 1,320Oct 13, 2025
mRNA-1083.1 VaccineCompletedNCT05827926SARS-CoV-2Phase 1 COMPLETED 1,758Dec 3, 2024
mRNA-1403 VaccineCompletedNCT05992935Norovirus Acute GastroenteritisPhase 1 COMPLETED 1,407Oct 7, 2026
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every MRNA program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
intismeran autogene (mRNA-4157/V940) melanomaPhase 32026-08-24met the primary endpoint of recurrence-free survivalRead MoreModerna and Merck Cancer Vaccine Success Is Good News for CancerVaxRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Hoge StephenOfficer (President)Option 76,452 1,675,710 held$12.21 10/15/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Casdin Capital, LLC 0.3 % 5.25 M 75.00 K
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Shares held by hedge funds each quarter, and who bought or sold.

MRNA Institutional Ownership Trends

MRNA Short Interest

Shares sold short, counted twice a month.

8.93%
Short % of Float
of tradable shares sold short
32.6M
Shares Sold Short
+5.6% vs prior count
1.8 Low
Days to Cover
trading days of normal volume to buy every short share back
18.3M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-30
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How MRNA ranks across every disease it competes in

Competitive Position is a premium feature
See how MRNA ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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MRNA News

MRNA
Oct 23, 2026
MRNAGeneral

Moderna Named a Top Employer by Science for Twelfth Consecutive Year

Moderna has been named a top employer in the biopharmaceutical industry for the twelfth consecutive year, according to Science's 2026 Top Employers Survey. The company was acknowledged for its strong corporate image and commitment to innovation. In 2026, Moderna also received approvals for two new vaccines and reported positive results from a Phase 3 cancer therapy trial.

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MRNA
Oct 13, 2026
MRNAConferences/Events

Moderna to Report Third Quarter 2026 Financial Results on Friday, November 6, 2026

Moderna, Inc. will report its third quarter 2026 financial results on November 6, 2026, during a live conference call at 8:00 a.m. ET. The event will also provide a corporate update. A webcast of the call will be available on Moderna's website, with an archived version accessible for one year.

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MRNA
Sep 30, 2026
MRNAGeneral
▼ -5.4%on this news

Moderna Adds Chief Operating Officer Role as Company Expands into Oncology

Moderna has appointed Juan Andres as Chief Operating Officer to enhance its operational capabilities as the company expands into oncology and prepares for the launch of intismeran autogene. This strategic move follows positive Phase 3 results and the recent approval of its seasonal flu vaccine. Jerh Collins is retiring after four years, leaving a strong legacy in technical operations.

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MRNA
Sep 21, 2026
MRNAConferences/Events
▲ +12.3%on this news· ran to +26% by day 3

Moderna Announces Late-Breaking Data to be Presented at ESMO Congress 2026

Moderna has announced that three abstracts on intismeran autogene, an investigational mRNA-based therapy, will be presented at the ESMO Congress 2026 in Madrid. This therapy targets patients with resected stage IIB-IV melanoma. Additionally, Moderna will host a live investor event on October 24 to discuss these findings.

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MRNA
Sep 1, 2026
MRNAConferences/Events
▲ +9.9%on this news

Moderna to Present at Upcoming Conferences in September 2026

Moderna, Inc. announced its participation in two upcoming investor conferences in September 2026. The conferences include the Morgan Stanley 24th Annual Global Healthcare Conference and the Bernstein Insights Healthcare Forum. Live webcasts will be available, and replays will be archived on Moderna's website. This highlights Moderna's ongoing commitment to mRNA medicine.

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MRNA
Aug 28, 2026
MRNAGeneral
▲ +9.9%on this newsshared move

Moderna Announces Pricing of Upsized $2.6 Billion Offering of Convertible Senior Notes

Moderna has announced the pricing of an upsized $2.6 billion offering of convertible senior notes due in 2032. The offering, initially set at $2.0 billion, will close on September 1, 2026. Proceeds will be used for general corporate purposes, including investments in oncology and debt repayment. The notes will be convertible under certain conditions.

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MRNA
Aug 24, 2026
MRNAPhases

Moderna and Merck Cancer Vaccine Success Is Good News for CancerVax

CancerVax, Inc. has welcomed the positive results from Moderna and Merck's Phase 3 trial of a personalized cancer vaccine for melanoma. The trial demonstrated the effectiveness of mRNA technology in mobilizing the immune system against cancer. CancerVax's approach differs by developing a universal cancer vaccine that leverages existing immunity, potentially simplifying treatment and reducing costs.

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MRNA
May 13, 2026
MRNAGeneral
▼ -5.4%on this news

Moderna Recognized by TIME as One of the World’s Most Impactful Companies

Moderna, Inc. has been recognized as the top company on TIME's 2026 list of the World's Most Impactful Companies, highlighting its advancements in mRNA technology and commitment to addressing significant health needs. CEO Stéphane Bancel emphasized the company's focus on innovative medicines and pandemic preparedness. Additionally, Moderna's recent approval for its flu and COVID combination vaccine marks a significant milestone in its product offerings.

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MRNA
May 1, 2026
MRNAGeneral

Moderna Reports First Quarter 2026 Financial Results and Provides Business Updates

Moderna, Inc. reported its financial results for the first quarter of 2026, revealing a revenue of $0.4 billion, driven significantly by international markets. Despite the strong revenue growth, the company faced a net loss of $(1.3) billion, largely due to a litigation settlement expense of $0.9 billion. Key progress included the approval of its combination flu and COVID vaccine in Europe, alongside the initiation of a Phase 3 trial for intismeran in treating high-risk Stage 1 non-small cell lung cancer. Management remains optimistic about future revenue growth and additional regulatory approvals.

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MRNA
Apr 7, 2026
MRNAConferences/Events

Moderna to Present Revaccination Data for Its Investigational Seasonal Influenza Vaccine and for mRESVIA at ESCMID 2026

Moderna, Inc. will present late-breaking data on its investigational seasonal influenza vaccine, mRNA-1010, and its RSV vaccine, mRESVIA, at the ESCMID 2026 Global Congress. The studies indicate that mRNA-1010 is safe and effective for older adults, while mRESVIA shows promise for revaccination. Both vaccines are under regulatory review in several countries.

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MRNA
Feb 27, 2026
MRNAFDA Updates

European Medicines Agency’s Committee for Medicinal Products for Human Use Adopts Positive Opinion Recommending Marketing Authorization of mCOMBRIAX, Moderna’s mRNA Combination Vaccine Against Influenza and COVID-19

Moderna's mCOMBRIAX, a combination vaccine for influenza and COVID-19, has received a positive opinion from the EMA's CHMP, marking a significant advancement in respiratory virus vaccination. This recommendation is based on successful Phase 3 trial results, indicating strong immune responses. The final marketing authorization will be decided by the European Commission.

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MRNA
Feb 19, 2026
MRNAConferences/Events
▲ +6.7%on this news

Moderna to Present at Upcoming Conferences in March 2026

Moderna, Inc. has announced its participation in two upcoming investor conferences in March 2026. The TD Cowen 46th Annual Healthcare Conference will take place on March 3, while the Barclays 28th Annual Global Healthcare Conference is scheduled for March 10. Both presentations will be available via live webcast and archived for 30 days on Moderna's website.

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MRNA
Feb 18, 2026
MRNAFDA Updates
▲ +6.1%on this newsshared move

Moderna Announces the U.S. Food and Drug Administration will Initiate the Review of Its Investigational Seasonal Influenza Vaccine Submission

Moderna's investigational seasonal influenza vaccine, mRNA-1010, has been accepted for review by the FDA following a Type A meeting. The company aims for full approval for adults aged 50 to 64 and accelerated approval for those 65 and older. The PDUFA goal date is set for August 5, 2026, with potential availability for the upcoming flu season.

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MRNA
Feb 17, 2026
MRNAFDA Updates

Moderna Receives European Commission Marketing Authorization for COVID-19 Vaccine mNEXSPIKE

Moderna has received marketing authorization from the European Commission for its COVID-19 vaccine mNEXSPIKE, aimed at individuals aged 12 and older. This marks the third vaccine authorized for Moderna in the EU, following Spikevax and mRESVIA. The authorization is based on positive Phase 3 trial results, showing mNEXSPIKE's efficacy and a favorable safety profile.

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MRNA
Feb 13, 2026
MRNAGeneral
▲ +5.3%on this news· ran to +24% by day 3shared move

Moderna Reports Fourth Quarter and Fiscal Year 2025 Financial Results and Provides Business Updates

Moderna reported its fourth quarter and full-year 2025 financial results, revealing a net loss of $2.8 billion and a 40% revenue decrease year-over-year. Despite these challenges, the company plans to achieve up to 10% revenue growth in 2026, supported by new product launches and strategic partnerships. Key updates include the full enrollment of clinical trials for Norovirus and muscle invasive bladder cancer, alongside ongoing regulatory reviews for its influenza vaccine.

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MRNA
Feb 11, 2026
MRNAFDA Updates

Moderna Receives Refusal-to-File Letter from the U.S. Food and Drug Administration for Its Investigational Seasonal Influenza Vaccine, mRNA-1010

Moderna announced that the FDA has issued a Refusal-to-File letter for its investigational influenza vaccine mRNA-1010, citing the choice of a licensed standard-dose vaccine comparator as the reason. The company plans to request a Type A meeting with the FDA to clarify the decision, which contradicts prior communications. Despite this setback, mRNA-1010 is under review in other countries, and Moderna does not anticipate any financial impact for 2026.

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MRNA
Feb 10, 2026
MRNAGeneral

Moderna to Enter into Long-Term Strategic Agreement with the Government of Mexico

Moderna has signed a Memorandum of Understanding with the Mexican Government and local partners to establish a long-term strategic agreement. This five-year collaboration aims to enhance Mexico's health security by providing access to Moderna's respiratory vaccine portfolio and facilitating technology transfer for local manufacturing of its COVID-19 vaccine. The initiative aligns with Mexico's 'Plan Mexico' to boost local production capacity and pandemic preparedness.

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MRNA
Jan 30, 2026
MRNAGeneral
▼ -6%on this newsshared move

Moderna Announces Strategic Collaboration with Recordati to Globally Commercialize Investigational Propionic Acidemia Therapeutic (mRNA-3927)

Moderna has announced a strategic collaboration with Recordati to advance its investigational therapeutic mRNA-3927 for propionic acidemia. Under the agreement, Moderna will lead clinical development while Recordati will handle global commercialization. The collaboration includes up to $160 million in payments and milestones, with a pivotal data readout expected in 2026. Propionic acidemia is a rare metabolic disorder with no current disease-modifying treatments.

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MRNA
Jan 27, 2026
MRNAConferences/Events
▼ -5.3%on this newsshared move

Moderna to Report Fourth Quarter 2025 Financial Results on Friday, February 13, 2026

Moderna, Inc. will host a live conference call on February 13, 2026, to discuss its fourth quarter 2025 financial results and provide a corporate update. The call will be accessible via a webcast on the company's website. An archived version of the call will be available for one year post-event.

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MRNA
Jan 20, 2026
MRNAPhases

Moderna & Merck Announce 5-Year Data for Intismeran Autogene in Combination With KEYTRUDA(R) (pembrolizumab) Demonstrated Sustained Improvement in the Primary Endpoint of Recurrence-Free Survival in Patients With High-Risk Stage III/IV Melanoma Following Complete Resection

Moderna and Merck have reported five-year follow-up data from the Phase 2b KEYNOTE-942/mRNA-4157-P201 study, showing that the combination of intismeran autogene and KEYTRUDA significantly reduces the risk of recurrence or death in patients with high-risk stage III/IV melanoma. The treatment demonstrated a 49% reduction in risk compared to KEYTRUDA alone. Further data will be presented at an upcoming medical conference, highlighting the potential of mRNA therapies in cancer care.

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About Moderna, Inc.

Cambridge, MA 4,700 employees modernatx.com
Headquarters325 BINNEY STREET, CAMBRIDGE, MA, 02142
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