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Johnson & Johnson

JNJ
OvervaluedPharma · Commercial
FDA catalysts, PDUFA dates & pipeline intelligence
$256.48
▼ -1.97 · -0.76%

Financials

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52W LOW $184.6652W HIGH $281.07
Volume
6.18 M
Value Traded
2.34 B
Short % Float
0.88%
+0.18%Week
-3.97%1 Month
-0.19%3 Month
+7.56%6 Month
+36.78%5 Year
+37,394.82%All Time

Cash Data

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  • SEC Filing

Key Stats

Market Cap
618.09 B
EPS (TTM)
8.73
P/E Ratio
29.38
Ent. Value
646.37 B
Total Shares
2.41 B
Float Shares
2.41 B
Insiders
0.12%
Institutions
77.22%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

JNJ Catalyst Timeline

Dated clinical, regulatory and corporate events for Johnson & Johnson

Catalyst Timeline

Dated clinical, regulatory & corporate events for Johnson & Johnson

2030Total events
23Upcoming
1024Tier-1 (high impact)
2010 to 2027Coverage

Upcoming catalysts 2

T1PDUFA Date
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IMAAVY™Approved
T2Quarterly Update
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Event history 50

▲CHMP Positive OpinionTECVAYLIApprovedEx-US Regulatory
CHMP empfiehlt Zulassung einer Indikationserweiterung für TECVAYLI (teclistamab) bei RRMM nach mindestens einer vorherigen Therapie
rezidiviertes oder refraktäres multiples Myelom (RRMM)source ↗
▲Topline ReadoutCAPLYTAApprovedClinical Data
Positive topline results from pivotal Phase 3 Study 451 of CAPLYTA in bipolar I mania
manic episodes with or without mixed features in adults with bipolar I disordersource ↗
▲Primary Endpoint MetCAPLYTAApprovedClinical Data
Study 451 met primary endpoint with statistically significant 4.8-point greater YMRS reduction vs placebo at Week 3
manic episodes with or without mixed features in adults with bipolar I disordersource ↗
▲Secondary Endpoint DataCAPLYTAApprovedClinical Data
Significant improvement in CGI-S illness severity vs placebo at Week 3 (LSMD -0.5; P<.0001)
manic episodes with or without mixed features in adults with bipolar I disordersource ↗
●Safety Data UpdateCAPLYTAApprovedClinical Data
CAPLYTA well-tolerated in Study 451 with safety profile consistent with established profile
manic episodes with or without mixed features in adults with bipolar I disordersource ↗
▲CHMP Positive OpinionTECVAYLIApprovedEx-US Regulatory
CHMP recommends approval of TECVAYLI indication extension for RRMM after ≥1 prior therapy
relapsed/refractory multiple myeloma after at least one prior therapysource ↗
●Late-BreakerCAPLYTAApprovedPresentation
Study 451 findings presented in late-breaking presentation at 2026 Psych Congress Annual Meeting
manic episodes with or without mixed features in adults with bipolar I disordersource ↗
▲Topline ReadoutAmivantamabApprovedClinical Data
Final overall survival analysis of PAPILLON: median OS 34.3 months with amivantamab plus chemotherapy
EGFR exon 20 insertion mutation-positive non-small cell lung cancersource ↗
▲Topline ReadoutRYBREVANT®ApprovedClinical Data
Final overall survival analysis of PAPILLON presented at IASLC 2026 WCLC Presidential Symposium
EGFR exon 20 insertion mutation-positive advanced non-small cell lung cancersource ↗
▲Oral PresentationRYBREVANT®ApprovedPresentation
PAPILLON final OS results presented at IASLC 2026 WCLC Presidential Symposium (Late-breaking Abstract #PL.03.03)
EGFR exon 20 insertion mutation-positive advanced non-small cell lung cancersource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How JNJ actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-08-28Stelara (ustekinumab) PDUFA Date ApprovedPDUFA
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

A87 / 100
Pipeline Score
$45.0B
Pipeline Value
$415.2B
Commercial Value
Overvalued
Valuation Signal
184
Drugs Scored
0.2x
rNPV / MCap
Top 1%
Large Pharma
(rank 8 of 658)
Percentile Rank
Johnson & Johnson earns an A-grade pipeline score (87/100), with $45.0B risk-adjusted pipeline value, led by acetaminophen Caplet in Post Operative Dental Pain (Phase 3).
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q)) Revenue $97.9B x 4.2 = $415.2B
ProductRevenuePrior periodChange
DARZALEX$15.7B$12.9B+22.3%
TREMFYA$6.7B$4.1B+62.7%
STELARA$4.2B$8.3B-49.5%
INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA$4.0B$4.0B-1%
ERLEADA$3.8B$3.3B+18%
IMBRUVICA$2.6B$2.9B-9.9%
Xarelto$2.6B$2.6B+1.9%
Simponi/Simponi Aria$2.6B$2.4B+5.6%
OPSUMIT/OPSYNVI$2.4B$2.3B+7.6%
CARVYKTI$2.3B$1.4B+63.4%
SPRAVATO$2.0B$1.3B+53.2%
UPTRAVI$2.0B$1.9B+5.5%
Top 12 of 22 product lines shown.
Showing 1 of 184 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
acetaminophen Caplet Small moleculeCompletedNCT02735122Post Operative Dental PainPhase 3 COMPLETED 420Oct 5, 2016
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Clinical Trial Results

Readouts, endpoints and source filings for every JNJ program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
IMAAVY
Priority
generalized myasthenia gravisPhase 2/32026-09-29mean change MG ADL: -2.88; mean change QMG: -8.25; corticosteroid reduction: initial patients 6, reduced dose 3, discontinued 1Read MoreJohnson & Johnson presents new data reinforcing sustained disease control and improved daily function achieved with IMAAVY® (nipocalimab-aahu) in generalized myasthenia gravis (gMG)Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Schmid TimothyOfficer (EVP, WW Chair, MedTech)Option 11,070 36,517 held$131.94 09/02/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
TRI LOCUM PARTNERS LP 13.3 % (-6.3 %) 107.92 M 424.94 K 2.52% ( 10.44 K)
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Shares held by hedge funds each quarter, and who bought or sold.

JNJ Institutional Ownership Trends

Options Data

Option Volume

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Put OI
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-06
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Real-Time Option Chain

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LastVolOILastVolOI
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Calls vs Puts by Expiry

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Competitive positioning

How JNJ ranks across every disease it competes in

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JNJ News

JNJ
Oct 2, 2026
JNJPhases

Johnson & Johnson announces new ICOTYDE® (icotrokinra) data in difficult-to-treat plaque psoriasis with proven durability through 2-years, affirming its use as a powerful first line systemic therapy

Johnson & Johnson has released new two-year data from the Phase 3 ICONIC-TOTAL study, demonstrating the effectiveness of ICOTYDE (icotrokinra) in treating high-impact plaque psoriasis. This targeted oral peptide shows sustained skin clearance and a favorable safety profile, making it a significant advancement in psoriasis treatment. The data were presented at the EADV Congress 2026, emphasizing its potential as a first-line systemic therapy.

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JNJ
Oct 1, 2026
JNJGeneral

New Global Survey by Johnson & Johnson Finds Most Women Don’t Connect Eye Health Changes with Menopause

Johnson & Johnson's new survey reveals that while most women understand menopause affects mood and sleep, only 40% associate it with changes in eye health. The survey highlights a significant gap in awareness, with many women not seeking necessary eye care. The company, alongside Naomi Watts and the American Optometric Association, aims to encourage women to prioritize eye health during midlife.

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JNJ
Sep 29, 2026
JNJPhases

Johnson & Johnson presents new data reinforcing sustained disease control and improved daily function achieved with IMAAVY® (nipocalimab-aahu) in generalized myasthenia gravis (gMG)

Johnson & Johnson has announced new data on IMAAVY (nipocalimab-aahu) for treating generalized myasthenia gravis (gMG), highlighting sustained disease control and improved patient outcomes over a two-year period. The findings indicate significant improvements in daily functioning and muscle strength, along with a reduction in corticosteroid use. Additionally, a survey revealed that many patients previously dissatisfied with their treatment experienced positive results after switching to IMAAVY.

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JNJ
Sep 25, 2026
JNJPhases

Johnson & Johnson announces TREMFYA® (guselkumab) is the first and only IL-23 inhibitor to show significant improvement in spinal pain and stiffness in landmark axial psoriatic arthritis (PsA) study

Johnson & Johnson announced that TREMFYA (guselkumab) is the first IL-23 inhibitor to demonstrate significant improvements in spinal pain and stiffness in the Phase 4 STAR study for patients with axial psoriatic arthritis. The study met primary and major secondary endpoints, showing both improvement in axial symptoms and reduction in inflammation. The findings support TREMFYA as a first-line treatment option for this patient population.

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JNJ
Sep 25, 2026
JNJPhases

Single infusion of CARVYKTI® (ciltacabtagene autoleucel) delivered five-year treatment-free remissions in 50% of patients in early line relapsed/refractory multiple myeloma

Johnson & Johnson announced that 50% of patients with early line relapsed/refractory multiple myeloma achieved five-year treatment-free remission after a single infusion of CARVYKTI (ciltacabtagene autoleucel) in the Phase 2 CARTITUDE-2 study. These results suggest that earlier treatment may enhance long-term remission rates. The safety profile remains consistent, with no new CAR T-cell-related neurotoxicity reported, although some patients experienced serious adverse events.

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JNJ
Sep 23, 2026
JNJPhases

New model-based analysis further supports the potential of TECVAYLI® (teclistamab-cqyv) plus DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) to redefine long-term survival expectations in early line relapsed/refractory multiple myeloma

Johnson & Johnson announced promising data from the Phase 3 MajesTEC-3 study, demonstrating that TECVAYLI (teclistamab-cqyv) combined with DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) significantly improves overall survival in patients with relapsed or refractory multiple myeloma. The study indicates that approximately 87% of patients may have a mortality risk comparable to that of the general population. The findings suggest a potential shift in long-term survival expectations for this patient group.

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JNJ
Sep 22, 2026
JNJFDA Updates

Der CHMP empfiehlt die Zulassung von TECVAYLI®▼ (teclistamab) von Johnson & Johnson zur Behandlung des rezidivierten bzw. refraktären multiplen Myeloms nach mindestens einer vorherigen Therapie

The CHMP has recommended the approval of TECVAYLI (teclistamab) by Johnson & Johnson for treating relapsed or refractory multiple myeloma (RRMM) after at least one prior therapy. This recommendation is based on positive results from a Phase III study demonstrating significant improvements in progression-free and overall survival compared to standard therapies. Teclistamab's potential to enhance treatment options for RRMM patients is emphasized, despite some concerns regarding infection rates and adverse events.

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JNJ
Sep 21, 2026
JNJPhases

CAPLYTA® (lumateperone) shows significant and rapid improvement in bipolar mania in pivotal Phase 3 study

Johnson & Johnson announced positive topline results from a pivotal Phase 3 study of CAPLYTA (lumateperone) for treating manic episodes in bipolar I disorder. The study demonstrated a significant reduction in symptoms as early as Day 3, with sustained improvements through Week 3. These findings support CAPLYTA's potential to effectively manage acute mania, although it is not yet approved for this indication.

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JNJ
Sep 18, 2026
JNJFDA Updates

CHMP recommends approval of Johnson & Johnson’s TECVAYLI®▼ (teclistamab) in relapsed/refractory multiple myeloma after at least one prior therapy

The CHMP has recommended the approval of Johnson & Johnson's TECVAYLI® (teclistamab) for adult patients with relapsed/refractory multiple myeloma who have received at least one prior therapy. This recommendation follows positive results from the Phase 3 MajesTEC-9 study, which demonstrated significant improvements in both progression-free and overall survival compared to standard treatments. The approval reflects a commitment to providing innovative therapies that address evolving patient needs in multiple myeloma.

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JNJ
Sep 15, 2026
JNJPhases

RYBREVANT FASPRO™ (amivantamab and hyaluronidase-lpuj) plus LAZCLUZE® (lazertinib) with prophylactic strategies shows low rates of treatment-related events at WCLC 2026

Johnson & Johnson reported positive results from the Phase 2b COPERNICUS study, showing that RYBREVANT FASPRO combined with LAZCLUZE results in low rates of treatment-related events for patients with advanced non-small cell lung cancer. The study emphasizes a patient-centric approach with less frequent dosing and effective prophylactic strategies. The findings were presented at the IASLC 2026 World Conference on Lung Cancer.

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JNJ
Sep 14, 2026
JNJPhases

Johnson & Johnson’s RYBREVANT®▼ (amivantamab) plus chemotherapy delivers median overall survival of nearly three years in EGFR exon 20 insertion mutation-positive non-small cell lung cancer

Johnson & Johnson announced that amivantamab combined with chemotherapy resulted in a median overall survival of 34.3 months for patients with EGFR exon 20 insertion mutation-positive non-small cell lung cancer. This marks a significant improvement over the 27.9 months median survival with chemotherapy alone. The results, presented at the IASLC 2026 World Conference, emphasize the treatment's potential to reset survival expectations for this challenging patient population.

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JNJ
Sep 13, 2026
JNJPhases

Johnson & Johnson's RYBREVANT® (amivantamab-vmjw) plus chemotherapy delivers longest reported median overall survival in EGFR exon 20 insertion mutation-positive lung cancer

Johnson & Johnson's RYBREVANT (amivantamab-vmjw) in combination with chemotherapy has shown promising results in the Phase 3 PAPILLON study for patients with advanced non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations. The treatment achieved a median overall survival of 34.3 months, significantly extending survival compared to chemotherapy alone, which had a median of 27.9 months. This represents a notable advancement for a patient population with historically low survival rates.

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JNJ
Sep 10, 2026
JNJGeneral

Johnson & Johnson reçoit le marquage CE pour les lentilles de contact réutilisables ACUVUE OASYS MAX

Johnson & Johnson has announced that it received CE marking for its new reusable contact lens, ACUVUE OASYS MAX 2-Week. This lens features exclusive MAX technologies aimed at providing enhanced comfort and visual clarity, even on day 14 of use. The product is set to launch in select European countries later this year, with a broader rollout planned for 2027.

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JNJ
Sep 10, 2026
JNJFDA Updates

Johnson & Johnson erhält CE-Kennzeichnung für wiederverwendbare Kontaktlinsen der Marke ACUVUE OASYS MAX

Johnson & Johnson has announced that it has received CE marking for its new ACUVUE OASYS MAX 2-Week reusable contact lenses. These lenses incorporate proprietary MAX technologies designed to provide exceptional comfort and clear vision even on the 14th day of use. The product is set to launch in select European countries later this year, with a broader rollout planned for 2027.

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JNJ
Sep 10, 2026
JNJFDA Updates

Resumen: Johnson & Johnson obtiene el marcado CE para las lentillas reutilizables ACUVUE OASYS MAX

Johnson & Johnson has announced the receipt of CE marking for its new ACUVUE OASYS MAX 2-Week reusable contact lenses. These lenses incorporate patented MAX technologies aimed at providing enhanced comfort and visual clarity for users, even on the 14th day of wear. This approval marks a significant advancement in their product line.

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JNJ
Sep 10, 2026
JNJFDA Updates

Riassunto: Johnson & Johnson riceve il marchio CE per le lenti a contatto riutilizzabili ACUVUE OASYS MAX

Johnson & Johnson has announced the receipt of the CE mark for its new ACUVUE OASYS MAX 2-Week reusable contact lenses. These lenses utilize proprietary MAX technologies to provide superior comfort and maintain clear vision even after 14 days of use. This approval marks a significant advancement in their product offerings.

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JNJ
Sep 10, 2026
JNJFDA Updates

Samenvatting: Johnson & Johnson ontvangt CE-markering voor herbruikbare ACUVUE OASYS MAX-contactlenzen

Johnson & Johnson has announced the receipt of CE marking for its new ACUVUE OASYS MAX 2-Week contact lenses. These reusable lenses incorporate MAX technologies aimed at providing enhanced comfort and visual clarity throughout their 14-day usage period. This approval marks a significant advancement in their product offerings.

Read more →
JNJ
Sep 10, 2026
JNJFDA Updates

Johnson & Johnson Receives CE Marking for ACUVUE OASYS MAX Reusable Contact Lenses

Johnson & Johnson has received CE Marking for its new ACUVUE OASYS MAX 2-Week reusable contact lenses, designed to enhance comfort and visual clarity. The lenses incorporate advanced MAX technologies and will be launched in select European markets starting late 2026, with broader availability planned for 2027. This product aims to meet the increasing demand for comfortable vision solutions in a digital world.

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JNJ
Sep 8, 2026
JNJConferences/Events

Johnson & Johnson spotlights new neuropsychiatry data across bipolar mania, depression and schizophrenia at Psych Congress 2026

Johnson & Johnson presented 24 abstracts at the 2026 Psych Congress, highlighting new clinical data on neuropsychiatry treatments. Key presentations included pivotal Phase 3 data for CAPLYTA in bipolar mania and analyses of SPRAVATO's effects on depressive symptoms. The company aims to enhance treatment options for patients facing significant challenges in managing mood disorders.

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JNJ
Sep 2, 2026
JNJConferences/Events

Johnson & Johnson to Participate in the Deutsche Bank 2026 Healthcare Summit

Johnson & Johnson will present at the Deutsche Bank 2026 Healthcare Summit on September 17, 2026. The management team will engage in a Fireside Chat at 12:00 p.m. Eastern Time. Investors can access a live audio webcast through the company's Investor Relations website, with an archived version available later.

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About Johnson & Johnson

New Brunswick, NJ 140,800 employees jnj.com
HeadquartersONE JOHNSON & JOHNSON PLZ, NEW BRUNSWICK, NJ, 08933
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