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Recombinant Human Erythropoietin

Phase 2

Breast Cancer | Small molecule | Oncology |Amgen Inc.|Last Updated: Dec 24, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

Recombinant Human Erythropoietin · 3 trials · 5 indications

Phase 2 3
NCT00120679Treatment for Patients With Non-Small Cell Lung Cancer Who Developed Anemia Due to ChemotherapyNon-Small Cell Lung Cancer
COMPLETED- Analytics
NCT00120692Treatment for Patients Suffering From Anemia Due to ChemotherapyBreast Cancer
COMPLETED- Analytics
NCT00121030Treatment for Patients With Gynecological Malignancies Who Suffer From Anemia Due to ChemotherapyGynecological Malignancies
COMPLETED- Analytics
PHASE2COMPLETED
Treatment for Patients With Non-Small Cell Lung Cancer Who Developed Anemia Due to Chemotherapy
Non-Small Cell Lung CancerUnlock trial analytics
PHASE2COMPLETED
Treatment for Patients Suffering From Anemia Due to Chemotherapy
Breast CancerUnlock trial analytics
PHASE2COMPLETED
Treatment for Patients With Gynecological Malignancies Who Suffer From Anemia Due to Chemotherapy
Gynecological MalignanciesUnlock trial analytics

Study Endpoints

Primary Endpoints

Anemia correction

Secondary Endpoints

Patient preference
Activities of daily living
Activities of daily living, patient preference
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
darbepoetin alfaDRUG -
recombinant human erythropoietin (rHuEPO)DRUG -
Recombinant Human ErythropoietinDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: - Subjects receiving multi-cycle chemotherapy for non-small cell lung cancer - Anemia due to chemotherapy (hgb less than or equal to 11.0 g/dL) - Expected to receive greater than or equal to 8 additional weeks of chemotherapy as part of their planned treatment - Karnofsky Perform...

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Competitive Landscape -Breast Cancer 402 trials

Top 20 of 92 competitors

CompanyTickerTrialsLead PhaseDrugs
AstraZeneca PLCAZN47PHASE3Fulvestrant, Capivasertib
Merck & Co., Inc.MRK12PHASE3Pembrolizumab, Paclitaxel, Doxorubicin, Epirubicin, Cyclophosphamide
Eli Lilly and CompanyLLY27PHASE3Abemaciclib, Standard Adjuvant Endocrine Therapy
BioNTech SE Sponsored ADRBNTX7PHASE3DB-1303/BNT323, T-DM1
Gilead Sciences, Inc.GILD13PHASE3Sacituzumab Govitecan-hziy, Eribulin, Capecitabine Product, Gemcitabine, Vinorelbine
Novartis AG Sponsored ADRNVS30PHASE3Ribociclib
Pfizer Inc.PFE34PHASE3ARV-471, Fulvestrant
BeOne Medicines Ltd. Sponsored ADRONC5PHASE3BGB-43395, Letrozole, Abemaciclib, Palbociclib, Ribociclib
Olema Pharmaceuticals, Inc.OLMA5PHASE3Palazestrant, Fulvestrant, Anastrozole, Letrozole, Exemestane
Jazz Pharmaceuticals Public Limited CompanyJAZZ3PHASE3Zanidatamab, Trastuzumab, Eribulin, Vinorelbine, Gemcitabine
Celcuity Inc.CELC3PHASE3Gedatolisib, Palbociclib, Fulvestrant, Alpelisib
Relay Therapeutics, Inc.RLAY2PHASE3Zovegalisib, Capivasertib, Fulvestrant
GSK plc Sponsored ADRGSK2PHASE3Niraparib
Greenwich LifeSciences, Inc.GLSI1PHASE3GLSI-100
Bristol-Myers Squibb CompanyBMY5PHASE2Iza-bren, Nab-paclitaxel, Paclitaxel, Capecitabine, Carboplatin
BriaCell Therapeutics CorpBCTX2PHASE3SV-BR-1-GM, Cyclophosphamide, Interferon infiltration of the inoculation site, Retifanlimab, Treatment of Physician's Choice
Incyte CorporationINCY4PHASE2Ruxolitinib, Capecitabine, Regorafenib
Natera, Inc.NTRA3PHASE2Discontinuation of the anti-HER2 maintenance therapy
Puma Biotechnology, Inc.PBYI3PHASE2Neratinib, Loperamide, Colesevelam
Atossa Therapeutics, Inc.ATOS1PHASE2endoxifen, goserelin
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Frequently asked questions about Recombinant Human Erythropoietin

What is Recombinant Human Erythropoietin used for?

Recombinant Human Erythropoietin is being studied for the treatment of anemia in patients with certain cancers, including non-small cell lung cancer, breast cancer, and gynecological malignancies. It is administered to patients who develop anemia due to chemotherapy. The drug is currently in Phase 2 clinical development for these oncology indications.

Who makes Recombinant Human Erythropoietin?

Recombinant Human Erythropoietin is being developed by Amgen Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol AMGN. Amgen is conducting clinical trials to evaluate the drug's safety and efficacy in treating chemotherapy-induced anemia in cancer patients.

What phase is Recombinant Human Erythropoietin in?

Recombinant Human Erythropoietin is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The ongoing clinical program includes completed Phase 2 trials in patients with non-small cell lung cancer, breast cancer, and gynecological malignancies who have anemia due to chemotherapy.

What clinical trials is Recombinant Human Erythropoietin in?

Recombinant Human Erythropoietin has been studied in three completed Phase 2 clinical trials: NCT00120679 for non-small cell lung cancer patients with chemotherapy-induced anemia, NCT00120692 for breast cancer patients with anemia, and NCT00121030 for patients with gynecological malignancies and anemia. All trials enrolled adults aged 18 years and older.

Is Recombinant Human Erythropoietin the same as erythropoietin?

Recombinant Human Erythropoietin is a form of erythropoietin, a hormone that stimulates red blood cell production. It is produced through recombinant DNA technology. In the context of clinical trials, it is being evaluated for its ability to treat anemia in cancer patients undergoing chemotherapy.