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thiotepa

Phase 2

Breast Cancer | Small molecule | Oncology |Meridian Bioscience Inc|Last Updated: May 30, 2013

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

thiotepa · 1 trial · 1 indication

Phase 2 1
NCT00004900Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast CancerBreast Cancer
COMPLETED- Analytics
PHASE2COMPLETED
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer
Breast CancerUnlock trial analytics

Study Design & Arms

PurposeTREATMENT

Interventions

NameTypeDescription
filgrastimBIOLOGICAL -
anastrozoleDRUG -
carboplatinDRUG -
cisplatinDRUG -
cyclophosphamideDRUG -
etoposideDRUG -
thiotepaDRUG -
peripheral blood stem cell transplantationPROCEDURE -
radiation therapyRADIATION -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexFEMALE
Healthy VolunteersNo
Study Sites1

DISEASE CHARACTERISTICS: Histologically confirmed epithelial carcinoma of the breast metastatic to any organ except brain, including ipsilateral supraclavicular (not axillary) lymph nodes and chest wall No apocrine, adenocystic, squamous cell carcinoma, sarcoma, or lymphoma Measurable or evaluable d...

Countries:United States
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Competitive Landscape -Breast Cancer 402 trials

Top 20 of 92 competitors

CompanyTickerTrialsLead PhaseDrugs
AstraZeneca PLCAZN47PHASE3Fulvestrant, Capivasertib
Merck & Co., Inc.MRK12PHASE3Pembrolizumab, Paclitaxel, Doxorubicin, Epirubicin, Cyclophosphamide
Eli Lilly and CompanyLLY27PHASE3Abemaciclib, Standard Adjuvant Endocrine Therapy
BioNTech SE Sponsored ADRBNTX7PHASE3DB-1303/BNT323, T-DM1
Gilead Sciences, Inc.GILD13PHASE3Sacituzumab Govitecan-hziy, Eribulin, Capecitabine Product, Gemcitabine, Vinorelbine
Novartis AG Sponsored ADRNVS30PHASE3Ribociclib
Pfizer Inc.PFE34PHASE3ARV-471, Fulvestrant
BeOne Medicines Ltd. Sponsored ADRONC5PHASE3BGB-43395, Letrozole, Abemaciclib, Palbociclib, Ribociclib
Olema Pharmaceuticals, Inc.OLMA5PHASE3Palazestrant, Fulvestrant, Anastrozole, Letrozole, Exemestane
Jazz Pharmaceuticals Public Limited CompanyJAZZ3PHASE3Zanidatamab, Trastuzumab, Eribulin, Vinorelbine, Gemcitabine
Celcuity Inc.CELC3PHASE3Gedatolisib, Palbociclib, Fulvestrant, Alpelisib
Relay Therapeutics, Inc.RLAY2PHASE3Zovegalisib, Capivasertib, Fulvestrant
GSK plc Sponsored ADRGSK2PHASE3Niraparib
Greenwich LifeSciences, Inc.GLSI1PHASE3GLSI-100
Bristol-Myers Squibb CompanyBMY5PHASE2Iza-bren, Nab-paclitaxel, Paclitaxel, Capecitabine, Carboplatin
BriaCell Therapeutics CorpBCTX2PHASE3SV-BR-1-GM, Cyclophosphamide, Interferon infiltration of the inoculation site, Retifanlimab, Treatment of Physician's Choice
Incyte CorporationINCY4PHASE2Ruxolitinib, Capecitabine, Regorafenib
Natera, Inc.NTRA3PHASE2Discontinuation of the anti-HER2 maintenance therapy
Puma Biotechnology, Inc.PBYI3PHASE2Neratinib, Loperamide, Colesevelam
Atossa Therapeutics, Inc.ATOS1PHASE2endoxifen, goserelin
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Frequently asked questions about thiotepa

What is thiotepa used for in breast cancer?

Thiotepa is an investigational small molecule being studied for the treatment of breast cancer, specifically in women with metastatic breast cancer. It is being evaluated as part of a chemotherapy regimen combined with peripheral stem cell transplantation. The drug is currently in Phase 2 clinical development for this indication.

What does thiotepa target?

Thiotepa is a small molecule therapeutic being studied in oncology. Its specific molecular target has not been disclosed in the available clinical trial information. The drug is being investigated for its role in treating metastatic breast cancer as part of a chemotherapy and stem cell transplant regimen.

Who makes thiotepa?

Thiotepa is being developed by Meridian Bioscience Inc, a company listed on the stock exchange under the ticker VIVO. The company is conducting clinical research on this drug for the treatment of breast cancer.

What phase is thiotepa in?

Thiotepa is currently in Phase 2 clinical development for breast cancer. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still undergoing clinical trials to evaluate its safety and efficacy in patients.

What clinical trials is thiotepa in?

Thiotepa has been studied in one completed clinical trial, identified as NCT00004900. This Phase 2 trial evaluated chemotherapy plus peripheral stem cell transplantation in treating women with metastatic breast cancer. The trial was conducted in the United States and enrolled female patients aged 18 years and older.

Is thiotepa the same as other drugs?

Thiotepa is a distinct drug entity being developed by Meridian Bioscience Inc. No alternative names for this drug have been reported in the available clinical trial information. It is being studied specifically for its potential role in treating metastatic breast cancer.