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pamidronate disodium

Phase 2

Breast Cancer | Small molecule | Oncology |Meridian Bioscience Inc|Last Updated: May 30, 2013

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

pamidronate disodium · 1 trial · 1 indication

Phase 2 1
NCT00004906Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast CancerBreast Cancer
COMPLETED- Analytics
PHASE2COMPLETED
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer
Breast CancerUnlock trial analytics

Study Design & Arms

PurposeTREATMENT

Interventions

NameTypeDescription
filgrastimBIOLOGICAL -
anastrozoleDRUG -
carboplatinDRUG -
cisplatinDRUG -
cyclophosphamideDRUG -
docetaxelDRUG -
doxorubicin hydrochlorideDRUG -
etoposideDRUG -
pamidronate disodiumDRUG -
thiotepaDRUG -
peripheral blood stem cell transplantationPROCEDURE -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexFEMALE
Healthy VolunteersNo
Study Sites4

DISEASE CHARACTERISTICS: Histologically confirmed epithelial carcinoma of the breast Metastatic disease including ipsilateral supraclavicular lymph nodes and the chest wall (no axillary nodes) Measurable or evaluable (bone only) disease on exam or radiography No apocrine, adenocystic, squamous cell ...

Countries:United States
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Competitive Landscape -Breast Cancer 402 trials

Top 20 of 92 competitors

CompanyTickerTrialsLead PhaseDrugs
AstraZeneca PLCAZN47PHASE3Fulvestrant, Capivasertib
Merck & Co., Inc.MRK12PHASE3Pembrolizumab, Paclitaxel, Doxorubicin, Epirubicin, Cyclophosphamide
Eli Lilly and CompanyLLY27PHASE3Abemaciclib, Standard Adjuvant Endocrine Therapy
BioNTech SE Sponsored ADRBNTX7PHASE3DB-1303/BNT323, T-DM1
Gilead Sciences, Inc.GILD13PHASE3Sacituzumab Govitecan-hziy, Eribulin, Capecitabine Product, Gemcitabine, Vinorelbine
Novartis AG Sponsored ADRNVS30PHASE3Ribociclib
Pfizer Inc.PFE34PHASE3ARV-471, Fulvestrant
BeOne Medicines Ltd. Sponsored ADRONC5PHASE3BGB-43395, Letrozole, Abemaciclib, Palbociclib, Ribociclib
Olema Pharmaceuticals, Inc.OLMA5PHASE3Palazestrant, Fulvestrant, Anastrozole, Letrozole, Exemestane
Jazz Pharmaceuticals Public Limited CompanyJAZZ3PHASE3Zanidatamab, Trastuzumab, Eribulin, Vinorelbine, Gemcitabine
Celcuity Inc.CELC3PHASE3Gedatolisib, Palbociclib, Fulvestrant, Alpelisib
Relay Therapeutics, Inc.RLAY2PHASE3Zovegalisib, Capivasertib, Fulvestrant
GSK plc Sponsored ADRGSK2PHASE3Niraparib
Greenwich LifeSciences, Inc.GLSI1PHASE3GLSI-100
Bristol-Myers Squibb CompanyBMY5PHASE2Iza-bren, Nab-paclitaxel, Paclitaxel, Capecitabine, Carboplatin
BriaCell Therapeutics CorpBCTX2PHASE3SV-BR-1-GM, Cyclophosphamide, Interferon infiltration of the inoculation site, Retifanlimab, Treatment of Physician's Choice
Incyte CorporationINCY4PHASE2Ruxolitinib, Capecitabine, Regorafenib
Natera, Inc.NTRA3PHASE2Discontinuation of the anti-HER2 maintenance therapy
Puma Biotechnology, Inc.PBYI3PHASE2Neratinib, Loperamide, Colesevelam
Atossa Therapeutics, Inc.ATOS1PHASE2endoxifen, goserelin
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Frequently asked questions about pamidronate disodium

What is pamidronate disodium used for in breast cancer?

Pamidronate disodium is a small molecule being studied for use in breast cancer, specifically in women with metastatic breast cancer. It is being investigated as part of a combination chemotherapy regimen followed by peripheral stem cell transplantation. The drug is currently in Phase 2 clinical development.

What does pamidronate disodium target?

Pamidronate disodium is a bisphosphonate that targets bone resorption by inhibiting osteoclast activity. In the context of breast cancer, it is being studied for its potential role in managing bone metastases. The drug's mechanism involves reducing bone turnover and potentially preventing skeletal-related events.

Who makes pamidronate disodium?

Pamidronate disodium is being developed by Meridian Bioscience Inc, which trades under the ticker VIVO. The company is conducting clinical research on this drug for the treatment of breast cancer. As of the latest data, the drug is in Phase 2 development.

What phase is pamidronate disodium in?

Pamidronate disodium is in Phase 2 clinical development for breast cancer. It is an investigational drug, meaning it has not yet been approved by regulatory authorities. The drug is being studied in a completed Phase 2 trial for metastatic breast cancer.

What clinical trials is pamidronate disodium in?

Pamidronate disodium has been studied in one clinical trial, NCT00004906, titled 'Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer.' This Phase 2 trial was completed in the United States and enrolled female patients aged 18 years and older.

Is pamidronate disodium the same as pamidronate?

Pamidronate disodium is the disodium salt form of pamidronate, a bisphosphonate medication. While the data provided does not list alternative names, pamidronate disodium is commonly known as pamidronate in clinical contexts. The drug is being investigated for its role in breast cancer treatment.