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oxaliplatine/ gemcitabine/ Vinorelbine

Phase 2

Non Small Cell Lung Cancer | Small molecule | Oncology |Sanofi|Trials Updated: Dec 7, 2009

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment40

FDA Designations

No designations recorded

oxaliplatine/ gemcitabine/ Vinorelbine clinical trials

oxaliplatine/ gemcitabine/ Vinorelbine · 1 trial · 1 indication

Phase 2 1
NCT00271271Efficacy Study of GEMOX Combination and Vinorelbine in NSCL PatientsNon Small Cell Lung Cancer
COMPLETED40 Analytics
PHASE2COMPLETED
Efficacy Study of GEMOX Combination and Vinorelbine in NSCL Patients
Non Small Cell Lung CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Objective rate of response (ORR) according to the RECIST criterion, as evaluated by a review panel of outside experts.

Secondary Endpoints

Progression free survival (PFS), Overall survival (OS)
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
oxaliplatine / gemcitabine / VinorelbineDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Non-small cell bronchopulmonary cancer established by histological and/or cytological methods; * Advanced or metastatic disease (stage IIIB or IV); * At least one measurable lesion with one dimension (\>= 20 mm by CT scan or \>=10 mm by CT scan) outside of the irradiated area;...

Countries:France
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Competitive Landscape -Non-Small Cell Lung Cancer 544 trials (matched to "Non Small Cell Lung Cancer")

Top 20 of 90 competitors

CompanyTickerTrialsLead PhaseDrugs
Merck & Co., Inc.MRK37PHASE3Pembrolizumab, Olaparib, Sacituzumab tirumotecan, Intismeran autogene, Pembrolizumab Berahyaluronidase alfa
Revolution Medicines, Inc.RVMD9PHASE3Daraxonrasib, Zoldonrasib, Elironrasib, RMC-5127
Eli Lilly and CompanyLLY18PHASE3Selpercatinib, Pemetrexed, Abemaciclib, Olomorasib, LY3537982
AbbVie, Inc.ABBV12PHASE3Telisotuzumab vedotin, ABBV-1480, Livmoniplimab, Budigalimab, Telisotuzumab Adizutecan
AstraZeneca PLCAZN68PHASE3Datopotamab deruxtecan, Durvalumab, Oleclumab, Monalizumab, Tremelimumab
Gilead Sciences, Inc.GILD7PHASE3Sacituzumab govitecan, Zimberelimab, Domvanalimab, Etrumadenant, TUB-040- Dose escalation
Bristol-Myers Squibb CompanyBMY24PHASE3Repotrectinib, Nivolumab, Pumitamig, Relatlimab, Adagrasib
Johnson & JohnsonJNJ19PHASE3Lazertinib, Amivantamab, JNJ-90301900, JNJ-86974680, Cetrelimab
BioNTech SE Sponsored ADRBNTX7PHASE3Gotistobart, Pumitamig, BNT326, BNT116, BNT324
Pfizer Inc.PFE20PHASE3Lorlatinib, Crizotinib, Avelumab, Talazoparib, Axitinib
ArriVent BioPharma, Inc.AVBP9PHASE3Firmonertinib
Amgen Inc.AMGN4PHASE3ABP 234, Sotorasib, Anvumetostat
Novartis AG Sponsored ADRNVS11PHASE3Opnurasib, TNO155, DKY709, Spartalizumab, KFA115
GSK plc Sponsored ADRGSK3PHASE3Dostarlimab, Belrestotug, Nelistotug, Cobolimab
Summit Therapeutics IncSMMT2PHASE3Ivonescimab
Nuvation Bio, Inc. Class ANUVB4PHASE3Taletrectinib
Genmab A/S Sponsored ADRGMAB4PHASE3Acasunlimab, Rina-S, GEN1042
Regeneron Pharmaceuticals, Inc.REGN7PHASE2Cemiplimab, Marlotamig, Fianlimab, REGN5093
Nuvalent, Inc. Class ANUVL1PHASE3Neladalkib
BeOne Medicines Ltd. Sponsored ADRONC7PHASE3Tislelizumab, BGB-A445, LBL-007, BGB-15025, BGB-43395
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Frequently asked questions about oxaliplatine/ gemcitabine/ Vinorelbine

What is oxaliplatine/gemcitabine/Vinorelbine used for?

This combination regimen was studied for Non Small Cell Lung Cancer. It combines three small molecule chemotherapy agents: oxaliplatine, gemcitabine, and Vinorelbine. The regimen was evaluated in a Phase 2 trial conducted in France in adults aged 18 years and older.

Who is developing oxaliplatine/gemcitabine/Vinorelbine?

Sanofi, which trades under the ticker SNY, is the developer associated with this oxaliplatine, gemcitabine, and Vinorelbine combination regimen for Non Small Cell Lung Cancer. The program was studied in a single Phase 2 clinical trial.

What phase is oxaliplatine/gemcitabine/Vinorelbine in?

Oxaliplatine/gemcitabine/Vinorelbine is in Phase 2 development for Non Small Cell Lung Cancer. The one registered trial for this combination, NCT00271271, has completed. It is an investigational regimen and is not described as approved.

What clinical trial is oxaliplatine/gemcitabine/Vinorelbine in?

The regimen was studied in NCT00271271, titled Efficacy Study of GEMOX Combination and Vinorelbine in NSCL Patients. This Phase 2 trial enrolled 40 participants with Non Small Cell Lung Cancer in France. It was an uncontrolled, non-randomized, open-label study in adults aged 18 years and older, and it has completed.

How many trials has oxaliplatine/gemcitabine/Vinorelbine been studied in?

Oxaliplatine/gemcitabine/Vinorelbine has been studied in one registered clinical trial, NCT00271271, which is completed. That Phase 2 study enrolled 40 participants with Non Small Cell Lung Cancer in France and used an uncontrolled design without randomization or blinding.