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tacedinaline

Phase 3

Lung Cancer | Small molecule | Oncology |Pfizer, Inc.|Last Updated: Aug 10, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

tacedinaline · 2 trials · 2 indications

Phase 3 1Phase 2 1
NCT00005093Gemcitabine With or Without CI-994 in Treating Patients With Advanced Non-small Cell Lung CancerLung Cancer
COMPLETED- Analytics
PHASE3COMPLETED
Gemcitabine With or Without CI-994 in Treating Patients With Advanced Non-small Cell Lung Cancer
Lung CancerUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
PurposeTREATMENT

Interventions

NameTypeDescription
gemcitabine hydrochlorideDRUG -
tacedinalineDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites16

DISEASE CHARACTERISTICS: Histologically or cytologically confirmed recurrent, locally advanced, or metastatic, unresectable non-small cell lung cancer Failed or relapsed after one prior platinum containing regimen (cisplatin or carboplatin) as first line therapy Prior brain metastases allowed if res...

Countries:United StatesCanada
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Competitive Landscape -Lung Cancer 281 trials

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Frequently asked questions about tacedinaline

What is tacedinaline used for?

Tacedinaline is an investigational small molecule being studied for the treatment of lung cancer and pancreatic cancer. It is being developed by Pfizer, Inc. (NYSE: PFE). The drug is in clinical development and is not approved by the FDA.

What does tacedinaline target?

Tacedinaline is a small molecule that was studied in combination with gemcitabine for advanced non-small cell lung cancer and advanced pancreatic cancer. Its specific molecular target is not disclosed in the available information.

Who makes tacedinaline?

Tacedinaline is being developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The drug is an investigational small molecule for oncology indications.

What phase is tacedinaline in?

Tacedinaline has been studied in clinical trials, including a Phase 3 trial for advanced non-small cell lung cancer. It remains investigational and is not FDA approved. The drug is not currently in active clinical trials.

What clinical trials is tacedinaline in?

Tacedinaline has been evaluated in two completed clinical trials. NCT00004861 studied gemcitabine with or without tacedinaline in advanced pancreatic cancer. NCT00005093 studied gemcitabine with or without tacedinaline in advanced non-small cell lung cancer.

Is tacedinaline the same as CI-994?

Yes, tacedinaline is also known as CI-994. Clinical trials for the drug used the name CI-994 in their titles, such as NCT00005093 for lung cancer and NCT00004861 for pancreatic cancer.