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ALIMTA plus Epirubicin

Phase 1

Breast Cancer | Small molecule | Oncology |Eli Lilly and Company|Last Updated: Jul 19, 2006

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

ALIMTA plus Epirubicin · 1 trial · 1 indication

Phase 1 1
NCT00097383Study of Alimta and Epirubicin Administered in Patients With Locally Advanced or Metastatic Breast CancerBreast Cancer
COMPLETED- Analytics
PHASE1COMPLETED
Study of Alimta and Epirubicin Administered in Patients With Locally Advanced or Metastatic Breast Cancer
Breast CancerUnlock trial analytics

Study Design & Arms

AllocationNON_RANDOMIZED
PurposeTREATMENT

Interventions

NameTypeDescription
ALIMTA plus EpirubicinDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexFEMALE
Healthy VolunteersNo
Study Sites25

Inclusion Criteria: * Diagnosis of locally advanced or metastatic breast cancer not amenable to local treatment. * Patients must be chemo-naive or have only neoadjuvant and/or adjuvant chemotherapy. * Patients must have at least one measurable lesion in an area not previously irradiated. * No chemo...

Countries:ArgentinaBelgiumBrazilMexicoPortugal
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Competitive Landscape -Breast Cancer 402 trials

Top 20 of 92 competitors

CompanyTickerTrialsLead PhaseDrugs
AstraZeneca PLCAZN47PHASE3Fulvestrant, Capivasertib
Merck & Co., Inc.MRK12PHASE3Pembrolizumab, Paclitaxel, Doxorubicin, Epirubicin, Cyclophosphamide
Eli Lilly and CompanyLLY27PHASE3Abemaciclib, Standard Adjuvant Endocrine Therapy
BioNTech SE Sponsored ADRBNTX7PHASE3DB-1303/BNT323, T-DM1
Gilead Sciences, Inc.GILD13PHASE3Sacituzumab Govitecan-hziy, Eribulin, Capecitabine Product, Gemcitabine, Vinorelbine
Novartis AG Sponsored ADRNVS30PHASE3Ribociclib
Pfizer Inc.PFE34PHASE3ARV-471, Fulvestrant
BeOne Medicines Ltd. Sponsored ADRONC5PHASE3BGB-43395, Letrozole, Abemaciclib, Palbociclib, Ribociclib
Olema Pharmaceuticals, Inc.OLMA5PHASE3Palazestrant, Fulvestrant, Anastrozole, Letrozole, Exemestane
Jazz Pharmaceuticals Public Limited CompanyJAZZ3PHASE3Zanidatamab, Trastuzumab, Eribulin, Vinorelbine, Gemcitabine
Celcuity Inc.CELC3PHASE3Gedatolisib, Palbociclib, Fulvestrant, Alpelisib
Relay Therapeutics, Inc.RLAY2PHASE3Zovegalisib, Capivasertib, Fulvestrant
GSK plc Sponsored ADRGSK2PHASE3Niraparib
Greenwich LifeSciences, Inc.GLSI1PHASE3GLSI-100
Bristol-Myers Squibb CompanyBMY5PHASE2Iza-bren, Nab-paclitaxel, Paclitaxel, Capecitabine, Carboplatin
BriaCell Therapeutics CorpBCTX2PHASE3SV-BR-1-GM, Cyclophosphamide, Interferon infiltration of the inoculation site, Retifanlimab, Treatment of Physician's Choice
Incyte CorporationINCY4PHASE2Ruxolitinib, Capecitabine, Regorafenib
Natera, Inc.NTRA3PHASE2Discontinuation of the anti-HER2 maintenance therapy
Puma Biotechnology, Inc.PBYI3PHASE2Neratinib, Loperamide, Colesevelam
Atossa Therapeutics, Inc.ATOS1PHASE2endoxifen, goserelin
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Frequently asked questions about ALIMTA plus Epirubicin

What is ALIMTA used for?

ALIMTA is an investigational oncology drug being studied for use in lung neoplasms, colorectal cancer, non-small-cell lung cancer, metastases, urologic neoplasms, and breast cancer. It is a small molecule developed by Eli Lilly and Company. Clinical trials have explored it in combination with other agents for these cancer types.

Who makes ALIMTA?

ALIMTA is developed by Eli Lilly and Company, a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol LLY. The drug is being investigated for multiple oncology indications including lung cancer, urologic neoplasms, and breast cancer.

What phase is ALIMTA in?

ALIMTA is in Phase 2 clinical development. It is an investigational drug and is not approved by the FDA. Two Phase 2 trials have been completed, along with one Phase 1 trial, all of which are now finished.

What clinical trials is ALIMTA in?

ALIMTA has been studied in several completed clinical trials. NCT00034593 tested ALIMTA plus gemcitabine in transitional cell carcinoma of the urothelium. NCT00051493 evaluated ALIMTA plus carboplatin in non-small-cell lung cancer. NCT00051506 studied ALIMTA with cisplatin or carboplatin in small cell lung cancer. NCT00097383 examined ALIMTA with epirubicin in breast cancer.

Is ALIMTA the same as pemetrexed?

ALIMTA is also known as pemetrexed. Clinical trial titles refer to ALIMTA (Pemetrexed) in combination with other chemotherapy agents. The drug is being investigated for multiple cancer types including non-small-cell lung cancer and breast cancer.