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fluoropyrimidine

Phase 2

Colorectal Cancer | Small molecule | Oncology |Sanofi|Last Updated: Oct 15, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment373

FDA Designations

No designations recorded

Clinical trial landscape

fluoropyrimidine · 1 trial · 1 indication

Phase 2 1
NCT00399750TREE-2: Three Regimens of Eloxatin in Advanced Colorectal CancerColorectal Cancer
COMPLETED373 Analytics
PHASE2COMPLETED
TREE-2: Three Regimens of Eloxatin in Advanced Colorectal Cancer
Colorectal CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

To evaluate the safety and efficacy of three oxaliplatin-fluoropyrimidine regimens when combined with bevacizumab as therapy for previously untreated metastatic colorectal cancer (TREE 2)

Secondary Endpoints

The overall incidence of grade 3 and grade 4 adverse events during the first 12 weeks of treatment for each of the oxaliplatin-fluoropyrimidine regimens used without bevacizumab (TREE1)
Type, frequency, severity, timing, and relatedness of all adverse events during treatment and for 30 days following discontinuation of treatment for each of the oxaliplatin-fluoropyrimidine regimens when used with or without bevacizumab(TREE1 and TREE2)
Actual treatment administration as characterized by median, mean, and range of doses given; dose modifications, omissions, and delays; and actual and relative dose intensity (TREE1 and TREE2)
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
oxaliplatinDRUG -
fluoropyrimidineDRUG -
bevacizumabDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

The following information on clinical trials is provided for information purposes only to allow patients and physicians to have an initial discussion about the trial. This information is not intended to be complete information about the trial, to contain all considerations that may be relevant to po...

Countries:United States
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Frequently asked questions about fluoropyrimidine

What is fluoropyrimidine used for in colorectal cancer?

Fluoropyrimidine is an investigational small molecule being studied for the treatment of colorectal cancer. It is currently in Phase 2 clinical development. The drug is being evaluated in patients with colorectal cancer, and it is not yet approved by regulatory authorities.

Who makes fluoropyrimidine?

Fluoropyrimidine is being developed by Sanofi, a biopharmaceutical company listed on the stock exchange under the ticker SNY. Sanofi is conducting clinical trials to evaluate the drug's safety and efficacy in patients with colorectal cancer.

What phase is fluoropyrimidine in?

Fluoropyrimidine is currently in Phase 2 clinical development for the treatment of colorectal cancer. It is an investigational drug, meaning it has not yet been approved by regulatory agencies. The drug is being studied in a clinical trial to assess its effects in patients.

What clinical trials is fluoropyrimidine in?

Fluoropyrimidine is being studied in a Phase 2 clinical trial with the identifier NCT00399750, titled 'TREE-2: Three Regimens of Eloxatin in Advanced Colorectal Cancer'. This trial has been completed and enrolled 373 participants with colorectal cancer in the United States.

Is fluoropyrimidine the same as Eloxatin?

Fluoropyrimidine is a drug being developed by Sanofi, and it is being studied in a clinical trial that includes Eloxatin as part of the treatment regimens. However, the data provided does not indicate that fluoropyrimidine and Eloxatin are the same drug.