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IDC-G305

Phase 1

Melanoma | Monoclonal antibody | Oncology |Design Therapeutics, Inc.|Last Updated: Aug 17, 2017

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment13

FDA Designations

No designations recorded

Clinical trial landscape

IDC-G305 · 1 trial · 5 indications

Phase 1 1
NCT02015416A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic CancerMelanoma
COMPLETED13 Analytics
PHASE1COMPLETED
A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer
MelanomaUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability
Up to 1 year after last vaccination

To evaluate the safety and tolerability of multiple ascending doses of intramuscular (IM) IDC-G305

Secondary Endpoints

Immunogenicity
Approximately 12 weeks
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Study Design & Arms

MaskingNONE
ModelSEQUENTIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
IDC-G305EXPERIMENTALNY-ESO-1 recombinant protein together with GLA-SE

Interventions

NameTypeDescription
IDC-G305BIOLOGICALNY-ESO-1 recombinant protein together with GLA-SE
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Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites4

Inclusion Criteria: * Confirmed diagnosis of melanoma, ovarian cancer, sarcoma, breast cancer or non-small cell lung cancer (NSCLC) * Unresectable, relapsed and/or metastatic cancer with minimal or low disease burden. Disease may or may not be measurable and should not be rapidly progressive. Inade...

Countries:United States
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Frequently asked questions about IDC-G305

What is IDC-G305 used for?

IDC-G305 is an investigational monoclonal antibody being developed for the treatment of melanoma. It is currently in Phase 1 clinical development. The drug is being studied in patients with unresectable or metastatic cancer, including melanoma, as part of an early-stage clinical trial.

Who is developing IDC-G305?

IDC-G305 is being developed by Design Therapeutics, Inc., a biopharmaceutical company. The company is listed on the stock exchange under the ticker symbol DSGN. The drug is currently in Phase 1 clinical development for the treatment of melanoma.

What phase is IDC-G305 in?

IDC-G305 is currently in Phase 1 clinical development. It is an investigational drug and has not yet been approved by regulatory authorities. The drug is being studied in an early-stage clinical trial to evaluate its safety and potential efficacy in patients with melanoma.

What clinical trials is IDC-G305 in?

IDC-G305 is associated with clinical trial NCT02015416, titled 'A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer'. This trial has been completed and enrolled 13 participants with conditions including melanoma, ovarian cancer, sarcoma, non-small cell lung cancer, and breast cancer.

Is IDC-G305 the same as NY-ESO-1?

IDC-G305 is not the same as NY-ESO-1. The clinical trial NCT02015416 involves NY-ESO-1 with GLA-SE, which is a different investigational therapy. IDC-G305 is a separate monoclonal antibody being developed by Design Therapeutics for melanoma, and it is not listed as an alternative name for NY-ESO-1.