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IO Biotech, Inc.

IOBT
Fair ValueBiotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$0
▲ +0.02 · +68.42%

Financials

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52W LOW $0.0352W HIGH $2.79
Volume
33.69 K
Value Traded
3.41
Short % Float
15.48%
-75.56%Week
-84.64%1 Month
-92.07%3 Month
-90.46%6 Month
-99.7%5 Year
-99.7%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
3.45 M
EPS (TTM)
-1.34
P/E Ratio
-
Ent. Value
-9.09 M
Total Shares
72.06 M
Float Shares
13.91 M
Insiders
16.12%
Institutions
40.08%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

IOBT Catalyst Timeline

Dated clinical, regulatory and corporate events for IO Biotech, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How IOBT actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-09-30Cylembio® (imsapepimut and etimupepimut, adjuvanted) Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D31 / 100
Pipeline Score
$3M
Pipeline Value
Fair Value
Valuation Signal
2
Drugs Scored
1.0x
rNPV / MCap
IO Biotech, Inc. faces pipeline headwinds (31/100), with $1.1B risk-adjusted pipeline value, led by IO102-IO103 in Lung Cancer Non Small Cell (Phase 2), across $58B in total addressable markets, but cash runway is a concern.
Showing 1 of 2 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
IO102-IO103 Small moleculeNCT05155254Metastatic MelanomaPhase 3 ACTIVE NOT_RECRUITING 407Sep 1, 2027
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Clinical Trial Results

Readouts, endpoints and source filings for every IOBT program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
IO102-IO103
Breakthrough
metastatic melanomaPhase 1/22025-12-15median progression free survival: 25.5 months; median overall survival: 60 months; median duration of response: more than 53 monthsRead MoreIO Biotech Announces Publication of Five-year Clinical Outcomes of Phase 1/2 Trial in Nature CommunicationsRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Hunter HeidiDirectorBuy 15,000 15,000 held$1.39 05/30/2025
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Ikarian Capital, LLC 0 % (-100 %) 81.00 K 1.39 M
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

IOBT Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

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LastVolOILastVolOI
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How IOBT ranks across every disease it competes in

Competitive Position is a premium feature
See how IOBT ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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IOBT News

About IO Biotech, Inc.

Copenhagen, G7 78 employees iobiotech.com
HeadquartersOLE MAALOES VEH 3, COPENHAGEN, G7, 2200
Founded2014
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