Recent Updates
Recently added Catalysts

Nebulized IVX-0142

Phase 2

Asthma | Small molecule | Respiratory |Teva Pharmaceutical Industries Limited|Last Updated: Nov 12, 2021

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment15
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00232999Efficacy/Safety Study of Nebulized IVX-0142, a Novel Antiallergic Drug, in Mild Allergic AsthmaPHASE2 COMPLETED 15Oct 1, 2005Jan 1, 2006Nov 12, 20213 Canada
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Serial lung function tests measured up to 7 hours post-allergen challenge to assess effects on early- and late-phase asthmatic reactions
Secondary Endpoints
Methacholine PC20 pre- and post-allergen challenge
Anti-inflammatory activity in airways
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingTRIPLE
ModelCROSSOVER
PurposePREVENTION
Interventions
NameTypeDescription
Nebulized IVX-0142DRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 60 Years
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: * Mild stable allergic asthma * Positive skin-prick test to at least one common aeroallergen * Positive methacholine challenge * Positive allergen-induced early- and late-phase airway bronchoconstriction * General good health Exclusion Criteria: * Lung diseases other than mild...

Countries:Canada
Unlock Eligibility Criteria