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852A

Phase 2

Melanoma | Small molecule | Oncology |Pfizer, Inc.|Last Updated: Oct 27, 2008

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials2
Total Enrollment28

FDA Designations

No designations recorded

Clinical trial landscape

852A · 2 trials · 2 indications

Phase 2 1Phase 1 1
NCT00189332Use of 852A in Metastatic Cutaneous Melanoma.Melanoma
COMPLETED28 Analytics
PHASE2COMPLETED
Use of 852A in Metastatic Cutaneous Melanoma.
MelanomaUnlock trial analytics

Study Endpoints

Primary Endpoints

assessing antitumor activity of 852A intravenous bolus injection administered 3 times a week for 12 weeks

Secondary Endpoints

to assess the safety of the dosage regiment over 12 weeks
to obtain preliminary data regarding the safety and long term efficacy of 852A in subjects treated with the drug for more than 12 weeks
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
852ADRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites8

Inclusion Criteria: * Advanced melanoma not responding to 1st line chemotherapy * Histological evidence of melanoma * Measurable disease according to RECIST criteria * ECOG performance status less than or equal to 2 * Life expectancy 6 months or more * Normal organ and bone marrow function as defin...

Countries:FranceGermanySwitzerlandUnited States
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Frequently asked questions about 852A

What is 852A used for in melanoma?

852A is an investigational small molecule being studied for the treatment of melanoma, including inoperable advanced melanoma skin lesions and unresectable metastatic cutaneous melanoma. It is an immune response modifier being evaluated in clinical trials for these conditions.

What does 852A target?

852A is an immune response modifier, a small molecule that modulates the immune system to fight cancer. Its specific molecular target is not disclosed in the available clinical trial information, but it is being studied for its safety and efficacy in treating melanoma skin lesions.

Who makes 852A?

852A is being developed by Pfizer, Inc., a biopharmaceutical company listed on the New York Stock Exchange under the ticker symbol PFE. Pfizer is conducting clinical trials to evaluate the drug's safety and efficacy in patients with melanoma.

What phase is 852A in?

852A is in Phase 2 clinical development for the treatment of melanoma. It has completed a Phase 1 trial and a Phase 2 trial, both of which are finished. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is 852A in?

852A has been studied in two completed clinical trials. NCT00091689 was a Phase 1 trial in the United States evaluating safety and efficacy in inoperable advanced melanoma skin lesions. NCT00189332 was a Phase 2 trial in France, Germany, and Switzerland for unresectable metastatic cutaneous melanoma, enrolling 28 participants.

Is 852A the same as any other drug?

852A is not known by any alternative names in the available clinical trial information. It is referred to solely as 852A in the studies registered under NCT00091689 and NCT00189332, which are the only trials associated with this investigational drug.