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recombinant interferon alfa

Phase 3

Leukemia | Monoclonal antibody | Oncology |Novartis AG|Last Updated: Jan 3, 2013

Success Probability

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

recombinant interferon alfa · 1 trial · 1 indication

Phase 3 1
NCT00006343STI571 Compared With Interferon Alfa Plus Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous LeukemiaLeukemia
COMPLETED- Analytics
PHASE3COMPLETED
STI571 Compared With Interferon Alfa Plus Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
LeukemiaUnlock trial analytics

Study Design & Arms

PurposeTREATMENT

Interventions

NameTypeDescription
recombinant interferon alfaBIOLOGICAL -
cytarabineDRUG -
imatinib mesylateDRUG -
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Eligibility Criteria

Age Range18 Years to 70 Years
SexALL
Healthy VolunteersNo
Study Sites1

DISEASE CHARACTERISTICS: Cytogenetically proven Philadelphia chromosome positive chronic phase chronic myelogenous leukemia (CML) Initial diagnosis within the past 6 months No prior chemotherapy, including regimens used in peripheral blood progenitor cell (PBPC) mobilization for PBPC transplantation...

Countries:United States
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Competitive Landscape -Leukemia 327 trials

Top 20 of 63 competitors

CompanyTickerTrialsLead PhaseDrugs
Amgen Inc.AMGN8PHASE3Blinatumomab, Low-intensity chemotherapy regimen
Eli Lilly and CompanyLLY9PHASE3Pirtobrutinib, Idelalisib, Bendamustine, Rituximab
BeOne Medicines Ltd. Sponsored ADRONC13PHASE3Sonrotoclax, Zanubrutinib, Venetoclax, Obinutuzumab
AbbVie, Inc.ABBV24PHASE3Venetoclax
AstraZeneca PLCAZN18PHASE3Acalabrutinib, Rituximab, Chlorambucil
Merck & Co., Inc.MRK7PHASE3Nemtabrutinib, Fludarabine, Cyclophosphamide, Bendamustine, Rituximab
Johnson & JohnsonJNJ12PHASE3Ibrutinib, Venetoclax, Chlorambucil, Obinutuzumab
Novartis AG Sponsored ADRNVS21PHASE3Imatinib, Nilotinib, Bosutinib, Dasatinib, Asciminib
Kura Oncology, Inc.KURA5PHASE3Ziftomenib, Venetoclax, Azacitidine, Daunorubicin, Cytarabine
Nurix Therapeutics, Inc.NRIX5PHASE3NX-5948, Pirtobrutinib
Syndax Pharmaceuticals IncSNDX4PHASE3Revumenib, Intensive Chemotherapy Regimen
Takeda Pharmaceutical Co. Ltd. Sponsored ADRTAK1PHASE3Ponatinib, Imatinib, Vincristine, Dexamethasone, Cytarabine
SELLAS Life Sciences Group, Inc.SLS1PHASE3Galinpepimut-S, Azacitidine, Venetoclax, Decitabine, Cytarabine
Grifols, S.A. Sponsored ADR Class BGRFS1PHASE3Xembify
Bristol-Myers Squibb CompanyBMY7PHASE2Azacitidine
Pfizer Inc.PFE6PHASE2Gemtuzumab ozogamicine- Cytarabine- Gilteritinib
Ascentage Pharma Group International Unsponsored ADRAAPG11PHASE3Olverembatinib
Tango Therapeutics, Inc.TNGX7PHASE3AG-120, Azacitidine
Incyte CorporationINCY6PHASE2Ruxolitinib
Actinium Pharmaceuticals, Inc. (Delaware)ATNM2PHASE3Iomab-B, Conventional Care
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Frequently asked questions about recombinant interferon alfa

What is recombinant interferon alfa used for?

Recombinant interferon alfa is used for the treatment of leukemia, specifically in the context of chronic myelogenous leukemia. It is being studied as a comparator in a clinical trial for patients with newly diagnosed chronic myelogenous leukemia. The drug is administered as part of an oncology treatment regimen.

Who makes recombinant interferon alfa?

Recombinant interferon alfa is developed by Novartis AG, a global healthcare company. Novartis is listed on the stock exchange under the ticker symbol NVS. The company is conducting clinical research on this drug for the treatment of leukemia.

What phase is recombinant interferon alfa in?

Recombinant interferon alfa is in Phase 3 clinical development. It is being evaluated in a completed Phase 3 trial for patients with newly diagnosed chronic myelogenous leukemia. The drug is investigational and has not been approved by regulatory authorities based on the available data.

What clinical trials is recombinant interferon alfa in?

Recombinant interferon alfa is associated with one clinical trial, NCT00006343, which is a Phase 3 study titled 'STI571 Compared With Interferon Alfa Plus Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia.' This trial has been completed and was conducted in the United States.

Is recombinant interferon alfa the same as STI571?

No, recombinant interferon alfa is not the same as STI571. In the clinical trial NCT00006343, STI571 is compared with recombinant interferon alfa plus cytarabine. STI571 is a separate drug being tested against the combination of recombinant interferon alfa and cytarabine in patients with newly diagnosed chronic myelogenous leukemia.