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INV-347

Phase 1

Obesity | Small molecule | Metabolic |Novo Nordisk A/S|Last Updated: Mar 6, 2026

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment91

FDA Designations

No designations recorded

Clinical trial landscape

INV-347 · 1 trial · 1 indication

Phase 1 1
NCT07153172Safety Follow-up Study of Participants Dosed With INV-347 in Study INV-CL-108Obesity
RECRUITING91 Analytics
PHASE1RECRUITING
Safety Follow-up Study of Participants Dosed With INV-347 in Study INV-CL-108
ObesityUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of adverse events
From the end-of-study participation in INV-CL-108 (week 0) to completion of the end-of-study visit (up to week 104 from enrolment)

Number of events

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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeOTHER

Treatment Arms

ArmTypeDescription
Participants from the study INV-CL-108EXPERIMENTALParticipants who were dosed with INV-347 in the First In Human study INV-CL-108 and still have measurable plasma exposure of INV-347 are included to assess long term safety.

Interventions

NameTypeDescription
INV-347DRUGParticipants who were dosed with INV-347 in the First In Human study INV-CL-108 and still have measurable plasma exposure of INV-347 are included to assess long term safety.
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study. 2. Male or female (sex at birth). 3. Age 18 years or above at the...

Countries:Canada
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Frequently asked questions about INV-347

What is INV-347 used for?

INV-347 is an investigational small molecule being developed for the treatment of obesity. It is currently in Phase 1 clinical development and is being studied in a safety follow-up trial in Canada. The drug is not yet approved and remains under investigation.

Who makes INV-347?

INV-347 is being developed by Novo Nordisk A/S, a biopharmaceutical company listed on the stock exchange under the ticker NVO. The company is conducting clinical trials to evaluate the safety and tolerability of this investigational small molecule for obesity.

What phase is INV-347 in?

INV-347 is in Phase 1 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities. A Phase 1 safety follow-up study is currently recruiting participants in Canada to further evaluate the drug's safety profile.

What clinical trials is INV-347 in?

INV-347 is being studied in a Phase 1 clinical trial with the identifier NCT07153172. This trial is a safety follow-up study of participants previously dosed with INV-347, enrolling 91 participants with obesity. The study is currently recruiting in Canada and is not randomized or blinded.

How does INV-347 work?

INV-347 is a small molecule, but its specific molecular target has not been disclosed. As a small molecule, it is designed to be taken orally and to interact with biological pathways involved in obesity, though the exact mechanism of action is not publicly detailed at this time.