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INV-347

Phase 1

Obesity | Small molecule | Metabolic |Novo Nordisk A/S|Last Updated: Mar 6, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment91
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07153172Safety Follow-up Study of Participants Dosed With INV-347 in Study INV-CL-108PHASE1 RECRUITING 91Aug 6, 2025Sep 15, 2027Mar 6, 20261 Canada
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Study Endpoints
Primary Endpoints
Number of adverse events
From the end-of-study participation in INV-CL-108 (week 0) to completion of the end-of-study visit (up to week 104 from enrolment)

Number of events

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeOTHER
Treatment Arms
ArmTypeDescription
Participants from the study INV-CL-108EXPERIMENTALParticipants who were dosed with INV-347 in the First In Human study INV-CL-108 and still have measurable plasma exposure of INV-347 are included to assess long term safety.
Interventions
NameTypeDescription
INV-347DRUGParticipants who were dosed with INV-347 in the First In Human study INV-CL-108 and still have measurable plasma exposure of INV-347 are included to assess long term safety.
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study. 2. Male or female (sex at birth). 3. Age 18 years or above at the...

Countries:Canada
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Recent Changes (Last 90 Days)
LOWMay 26, 2026NCT07153172primaryCompletionDate: changed
LOWMay 24, 2026NCT07153172studyFirstPostDate: changed