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Metsera, Inc.

MTSRFDA catalysts, PDUFA dates & pipeline intelligence
$70.5
▼ -0.24 · -0.34%

Last traded Nov 13, 2025. This price is not current.

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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52W LOW $12.3052W HIGH $83.86
Volume
27.91 M
Value Traded
1.96 B
Short % Float
10.36%
Days to Cover
2.5
-8.97%Week
+34.06%1 Month
+127.42%3 Month
+174.75%6 Month
+176.47%5 Year
+176.47%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
7.43 B
EPS (TTM)
-2.99
P/E Ratio
-
Ent. Value
6.98 B
Total Shares
105.06 M
Float Shares
46.05 M
Insiders
51.74%
Institutions
38.80%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

MTSR Catalyst Timeline

Dated clinical, regulatory and corporate events for Metsera, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How MTSR actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Showing 1 of 5 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
MET097 Small moleculeCompletedNCT07311850Obesity and OverweightPhase 1/2 ACTIVE NOT_RECRUITING 3,698Apr 25, 2028
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every MTSR program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
MET-097i obesityPhase 2b2025-09-29weight loss: 14.1%; nausea: 13%; vomiting: 11%; study discontinuation: 2.9%Read MoreMetsera Reports Positive Phase 2b Results for First- and Best-in-Class Ultra-long Acting GLP-1 RA Candidate MET-097i, Enabling Rapid Transition into Phase 3Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
FMR LLC10% Owner, See Remark 1Sell -193 2,356,081 held$61.23 11/03/2025
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
VR Adviser, LLC 11 % (37.5 %) 196.27 M 3.75 M
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

MTSR Short Interest

Shares sold short, counted twice a month.

10.36%
Short % of Float
of tradable shares sold short
4.8M
Shares Sold Short
-2.1% vs prior count
2.5 Moderate
Days to Cover
trading days of normal volume to buy every short share back
1.9M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How MTSR ranks across every disease it competes in

Competitive Position is a premium feature
See how MTSR ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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MTSR News

About Metsera, Inc.

Founded2025
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