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Palatin Technologies, Inc.

PTN
OvervaluedPharma · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$9.09
▲ +0.08 · +0.89%

Financials

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52W LOW $7.2152W HIGH $31.00
Volume
1.63 K
Value Traded
98.35 K
Short % Float
21.5%
-3.43%Week
-26.93%1 Month
-9.9%3 Month
-50%6 Month
-97.98%5 Year
-100%All Time

Cash Data

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Key Stats

Market Cap
16.17 M
EPS (TTM)
-4.71
P/E Ratio
-
Ent. Value
8.54 M
Total Shares
1.78 M
Float Shares
1.68 M
Insiders
5.59%
Institutions
49.63%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
IND Submission
once-weekly MC4R selective peptide agonist
hypothalamic obesity, Prader-Willi syndrome, Bardet-Biedl syndrome
INDPeptidesRare Diseases
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PoA blends historical approval base rates, trial design score and FDA review track record.

PTN Catalyst Timeline

Dated clinical, regulatory and corporate events for Palatin Technologies, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Palatin Technologies, Inc.

814Total events
9Upcoming
185Tier-1 (high impact)
2007 to 2027Coverage

Upcoming catalysts 2

T2IND Submission
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T2IND Submission
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Event history 50

●R&D DayPresentation
Palatin to host conference call and webcast to discuss fiscal 2026 financial results
●Quarterly UpdateCorporate
Palatin reported fiscal year 2026 financial results and business update
▼Going ConcernCorporate
Substantial doubt exists about ability to continue as a going concern
▲Quarterly UpdateCorporate
Begin trading on Nasdaq
▲Quarterly UpdateCorporate
Common stock approved for listing on Nasdaq Capital Market
●Quarterly UpdateCorporate
Fiscal Q3 2026 financial results and business update
●Oral PresentationPresentation
Conference call and webcast to discuss Q3 results
◆Topline ReadoutPL7737Clinical Data
Topline clinical data for PL7737 Phase 1 trial
obesitysource ↗
●IND SubmissionIND
IND filing for next-generation selective peptide MC4R agonist
obesitysource ↗
●Trial InitiationTrial
Initiation of Phase 1 SAD/MAD trial for next-generation peptide MC4R agonist
obesitysource ↗
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Past FDA Catalysts and PDUFA Decisions

How PTN actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-12-31next-generation oral MC4R selective agonist candidates IND Submission IND
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D38 / 100
Pipeline Score
$8M
Pipeline Value
Overvalued
Valuation Signal
3
Drugs Scored
0.5x
rNPV / MCap
Top 45%
Micro Cap
(rank 297 of 658)
Percentile Rank
Palatin Technologies, Inc. faces pipeline headwinds (38/100), with $771M risk-adjusted pipeline value, led by bremelanotide in Obesity (Phase 2).
Showing 1 of 3 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
bremelanotide Small moleculeMarketedNCT02333071Hypoactive Sexual Desire DisorderPhase 3 COMPLETED 1,437Jun 30, 2017
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Clinical Trial Results

Readouts, endpoints and source filings for every PTN program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
PL9643 dry eye diseasePhase 32025-04-296 of 13 symptom endpoints showed a significantly higher percentage of patients in the PL9643 group achieving complete symptom resolution compared to placebo (p<0.05); Statistically significant symptom resolution by week 2; Continued improvement through week 12 with no plateauRead MorePalatin Announces Breakthrough Symptom Resolution in Updated Analyses from Phase 3 PL9643 MELODY-1 Clinical Trial in Dry Eye DiseaseRead More
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Inside Trades

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InsiderSideSharesPriceValueDate
SPANA CARLDirector, Officer (President and CEO)Disposition -33 65,160 held$11.77 07/15/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
RA CAPITAL MANAGEMENT, L.P. 0 % 670.00 K 62.12 K -11.25% ( -7.88 K)
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Shares held by hedge funds each quarter, and who bought or sold.

PTN Institutional Ownership Trends

Options Data

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Open Interest
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Today vs avg
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How PTN ranks across every disease it competes in

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See how PTN ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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PTN News

PTN
Sep 28, 2026
PTNGeneral
▼ -5.1%on this news

Palatin Reports Fiscal Year 2026 Financial Results and Provides Business Update

Palatin Technologies reported its fiscal year 2026 financial results, highlighting its focus on developing therapies for rare obesity disorders linked to the melanocortin 4 receptor (MC4R). The company plans to initiate Phase 1 studies for both injectable and oral MC4R selective agonists in 2027 and 2028. Despite generating $13.2 million in collaboration revenue, Palatin faces funding challenges to sustain its operations and development programs.

Read more →
PTN
May 18, 2026
PTNGeneral
▲ +5.8%on this news

Palatin to Begin Trading on Nasdaq Stock Exchange

Palatin Technologies, Inc. has announced its common stock will transition from the NYSE American to the Nasdaq Capital Market on May 29, 2026. The company expects this move to enhance visibility and trading liquidity, as well as provide greater exposure to institutional investors. Palatin is focused on developing novel therapeutics targeting the melanocortin receptor system, particularly for rare obesity disorders. Their innovative programs include injectable and oral MC4R selective agonists with anticipated IND submissions approaching in late 2026 and early 2027.

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PTN
May 13, 2026
PTNGeneral
▼ -16%on this newsshared move

Palatin Reports Fiscal Third Quarter 2026 Financial Results and Provides Business Update

Palatin Technologies reported its fiscal third quarter 2026 financial results, highlighting advancements in its MC4R-based obesity programs. The company aims to submit IND applications for its MC4R selective peptide agonist and oral small molecule candidates in 2026 and 2027, respectively. Financially, Palatin recognized $3.9 million in collaboration revenue and reduced its net loss to $1.4 million, reflecting improved operational efficiency.

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PTN
Feb 17, 2026
PTNGeneral

Palatin Reports Second Quarter Fiscal Year 2026 Financial Results and Provides Corporate Update

Palatin Technologies has reported its financial results for the second quarter of fiscal year 2026, highlighting advancements in its MC4R-based obesity programs. The company is set to initiate clinical evaluations for its oral and long-acting peptide MC4R agonists. Despite a net loss of $7.3 million, Palatin has strengthened its balance sheet through a successful public offering and aims to address significant unmet medical needs in obesity treatment.

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PTN
Nov 13, 2025
PTNGeneral

Palatin Reports First Quarter Fiscal Year 2026 Financial Results and Provides Corporate Update

Palatin Technologies reported strong financial results for the first quarter of fiscal year 2026, highlighting significant advancements in its obesity pipeline, particularly with the oral small molecule PL7737. The company successfully closed an $18.2 million public offering, enhancing its financial position and enabling continued development of its melanocortin-based therapies. Additionally, Palatin's stock has resumed trading on the NYSE American, marking a positive turnaround for the company.

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PTN
Nov 12, 2025
PTNGeneral
▲ +10.6%on this news· ran to +28% by day 3shared move

Palatin Technologies Announces Closing of Upsized $18.2 Million Public Offering with the Full Exercise of the Underwriters' Over-Allotment Option

Palatin Technologies announced the successful closing of an $18.2 million public offering, which included the full exercise of the underwriters' over-allotment option. The offering was well-received, with participation from key institutional investors and company executives. The proceeds will support the development of Palatin's obesity program and general corporate purposes. Additionally, the company has regained compliance with NYSE American listing standards.

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PTN
Nov 6, 2025
PTNGeneral
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Technologies Announces Pricing of Upsized $15.8 Million Public Offering

Palatin Technologies has announced the pricing of an upsized public offering, raising $15.8 million. The offering includes common stock and warrants, with participation from institutional investors and company executives. The funds will support the development of its obesity program and help regain compliance with NYSE American listing standards. The offering is expected to close on November 12, 2025.

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PTN
Nov 6, 2025
PTNConferences/Events
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Presents Data at ObesityWeek® 2025 Highlighting Promise of Melanocortin-Based Therapies for Obesity

Palatin Technologies, Inc. presented promising data on the melanocortin receptor (MC4R) agonist PL7737 at ObesityWeek® 2025, showing its potential for significant weight loss and safety in preclinical models. Additionally, a Phase II study indicated that combining MC4R agonists with tirzepatide could enhance weight management without new safety issues. Ongoing studies are set to lead to an IND submission and clinical trials in early 2026. The company is committed to advancing innovative therapies for obesity, particularly for rare genetic conditions.

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PTN
Sep 22, 2025
PTNGeneral
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Earns €5.5 Million ($6.5 Million) Milestone Payment in Retinal Disease Collaboration with Boehringer Ingelheim

Palatin Technologies has achieved a significant milestone in its collaboration with Boehringer Ingelheim, earning a €5.5 million payment. This partnership focuses on developing innovative treatments targeting the melanocortin receptor system for retinal diseases, including diabetic retinopathy. The collaboration aims to address critical unmet medical needs in diabetes-related eye conditions.

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PTN
Sep 22, 2025
PTNGeneral
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Earns 5.5 Million ($6.5 Million) Milestone Payment in Retinal Disease Collaboration with Boehringer Ingelheim

Palatin Technologies has achieved a research milestone in its collaboration with Boehringer Ingelheim, earning a payment of $6.5 million. The focus of this collaboration is on developing first-in-class treatments targeting melanocortin receptors for retinal diseases like diabetic retinopathy. Palatin aims to address significant unmet medical needs and has the potential for substantial future milestone payments and royalties under the partnership. This achievement reflects Palatin's strategy to enhance its pipeline of melanocortin receptor agonists through strategic collaborations.

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PTN
Aug 8, 2025
PTNGeneral
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Announces 1-for-50 Reverse Stock Split

Palatin Technologies has announced a 1-for-50 reverse stock split effective August 8, 2025. This action is taken to boost the market price of its shares, assisting compliance with NYSE American's Listing Qualifications. The adjusted shares will begin trading under the new ticker PTNTD on the OTCQB Market starting August 11, 2025. Shareholders approved this decision at the annual meeting held on July 25, 2025. The reverse stock split will consolidate shares and provide cash for any fractional shares.

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PTN
Jul 15, 2025
PTNPhases
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Announces Positive Preclinical Efficacy Data for Oral MC4R Agonist PL7737 in Animal Model of Obesity

Palatin Technologies announced promising preclinical efficacy data for their oral MC4R agonist PL7737 in obesity treatment. In rodent models, PL7737 demonstrated significant weight loss, both as a monotherapy and in combination with tirzepatide. The company plans to begin clinical trials in late 2025, with preliminary data expected in early 2026. Additionally, PL7737 has received orphan drug designation for treating leptin receptor deficiency-related obesity.

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PTN
May 14, 2025
PTNGeneral
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Reports Fiscal Year 2025 Third Quarter Results and Business Update

Palatin Technologies reported strong operational results for Q3 of FY 2025, highlighting advancements in its obesity and ocular programs. The Phase 2 obesity study demonstrated effective weight reduction with a combination of therapies, while the Phase 3 ocular program achieved significant symptom resolution in dry eye patients. Despite these achievements, the company faces challenges such as the suspension and potential delisting from the NYSE American due to low stock price and reduced cash reserves. Moving forward, Palatin is focusing on securing funding to support ongoing operations and strategic initiatives.

Read more →
PTN
May 9, 2025
PTNPhases
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Presents Promising Preclinical Data on Melanocortin Agonists for Retinopathy at ARVO 2025

Palatin Technologies presented promising preclinical data on its melanocortin agonists PL9654 and PL9655 for the treatment of diabetic retinopathy at the ARVO Annual Meeting. The findings indicate these compounds can resolve inflammation, stabilize the blood-retinal barrier, and protect retinal ganglion cells. Notably, both agents demonstrated efficacy through multiple administration routes, including topical delivery, suggesting significant potential for earlier treatment interventions. Ongoing development of these melanocortin receptor-targeting therapies is supported by the results, highlighting their innovative approach to managing diabetic retinopathy.

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PTN
May 8, 2025
PTNGeneral
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Technologies Announces Closing of Reduced Public Offering

Palatin Technologies, Inc. announced the closing of a reduced public offering, securing approximately $1.1 million in gross proceeds. The offering involved 7,324,119 shares of common stock along with accompanying warrants. The company plans to use the net proceeds primarily for working capital and general corporate purposes. This event marks a continued effort by the company to bolster its financial standing and support its development endeavors.

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PTN
May 8, 2025
PTNPhases
▲ +11632.2%on this news· ran to +13428% by day 3shared move

Palatin Presents Breakthrough Symptom Resolution Data from Phase 3 PL9643 MELODY-1 Clinical Trial in Dry Eye Disease at ARVO 2025

Palatin Technologies presented promising data on PL9643 during the Phase 3 MELODY-1 trial for dry eye disease at the ARVO 2025. The analysis showed that PL9643 could achieve full symptom resolution across multiple endpoints, demonstrating significant efficacy as early as two weeks into treatment. The therapy also exhibited a strong safety profile, with adverse events comparable to vehicle control. These findings suggest that PL9643 could be a first-in-class treatment, addressing unmet needs in the dry eye disease market.

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PTN
May 7, 2025
PTNGeneral
▼ -44.6%on this news· ran to +6394% by day 1shared move

Palatin Technologies Announces Transition to OTC Pink Following NYSE American Delisting Notice

Palatin Technologies announced it will transition to the OTC Pink Market after receiving a delisting notice from NYSE American due to the low selling price of its stock. Trading on the NYSE American has been suspended, and the company plans to appeal the delisting determination. CEO Carl Spana expressed disappointment but maintained confidence in the company's valuable assets and continued commitment to its business plan. Palatin has until May 14, 2025, to file its appeal.

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About Palatin Technologies, Inc.

Cranbury, NJ 29 employees palatin.com
Headquarters4B CEDAR BROOK DRIVE, CRANBURY, NJ, 08512
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