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CC-1088

Phase 2

Myelodysplastic Syndrome | Small molecule | Oncology |Bristol-Myers Squibb Company|Last Updated: Apr 25, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedCONTROLLED
Total Trials1
Total Enrollment18

FDA Designations

No designations recorded

Clinical trial landscape

CC-1088 · 1 trial · 1 indication

Phase 2 1
NCT00045786Study to Determine the Safety and Preliminary Efficacy of CC-1088 in the Treatment of Myelodysplastic SyndromesMyelodysplastic Syndrome
COMPLETED18 Analytics
PHASE2COMPLETED
Study to Determine the Safety and Preliminary Efficacy of CC-1088 in the Treatment of Myelodysplastic Syndromes
Myelodysplastic SyndromeUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
400 mg CC-1088EXPERIMENTAL -
800 mg CC-1088EXPERIMENTAL -
1200 mg CC-1088EXPERIMENTAL -
1500 mg CC-1088EXPERIMENTAL -

Interventions

NameTypeDescription
CC-1088DRUG400 mg/day (200 mg orally twice a day) 800 mg/day (400 mg orally twice a day) 1200 mg/day (600 mg orally twice a day) 1500 mg/day (500 mg orally three times daily)
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Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Eligible patients must have a diagnosis of MDS of at least 12 weeks that is not therapy related. * Age ≥ 18 at the time of signing informed consent * Patient must be able to adhere to the study visit schedule and other protocol requirements. * Patient must understand and volun...

Countries:United States
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Frequently asked questions about CC-1088

What is CC-1088 used for in Myelodysplastic Syndrome?

CC-1088 is an investigational small molecule being studied for the treatment of Myelodysplastic Syndrome, a group of bone marrow disorders. It is currently in Phase 2 clinical development and is not yet approved by the FDA. The drug is being evaluated for its safety and preliminary efficacy in patients with this condition.

Who makes CC-1088?

CC-1088 is being developed by Bristol-Myers Squibb Company, a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol BMY. The company is conducting clinical research to evaluate the drug's potential in treating Myelodysplastic Syndrome.

What phase is CC-1088 in?

CC-1088 is in Phase 2 clinical development for Myelodysplastic Syndrome. It is an investigational drug, meaning it has not been approved by regulatory authorities. The Phase 2 trial has been completed, and the drug remains under investigation for this indication.

What clinical trials is CC-1088 in?

CC-1088 has one completed Phase 2 clinical trial registered under NCT00045786, titled 'Study to Determine the Safety and Preliminary Efficacy of CC-1088 in the Treatment of Myelodysplastic Syndromes.' The trial enrolled 18 participants in the United States and included patients aged 18 years and older.

Is CC-1088 FDA approved?

CC-1088 is not FDA approved. It is an investigational drug currently in Phase 2 clinical development for Myelodysplastic Syndrome. The completed Phase 2 trial assessed safety and preliminary efficacy, but the drug has not received regulatory approval for any use.