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ICI 182, 780

Phase 2

Systemic Lupus Erythematosus | Small molecule | Immunology |AstraZeneca PLC|Last Updated: Sep 22, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment20

FDA Designations

No designations recorded

Clinical trial landscape

ICI 182, 780 · 1 trial · 1 indication

Phase 2 1
NCT00417430Efficacy of Faslodex in Treatment of SLE Clinical, Serologic, and Molecular StudiesSystemic Lupus Erythematosus
COMPLETED20 Analytics
PHASE2COMPLETED
Efficacy of Faslodex in Treatment of SLE Clinical, Serologic, and Molecular Studies
Systemic Lupus ErythematosusUnlock trial analytics

Study Endpoints

Primary Endpoints

Improved SLEDAI
Improved Disease Lab parameters
Measurement of the estrogen receptors from start to finish
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
ICI 182,780 (Faslodex)DRUG -
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Eligibility Criteria

Age Range16 Years to 50 Years
SexFEMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Premenopausal women with SLE * Without life-threatening manifestations * With regular menstrual cyles not on hormones of any kind Exclusion Criteria: For any of the following: * Increase of SLEDAI greater than 12 * If life-threatening manifestations occur * If menstruation ...

Countries:United States
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Frequently asked questions about ICI 182, 780

What is ICI 182,780 used for?

ICI 182,780 is being studied for the treatment of Systemic Lupus Erythematosus (SLE). It is an investigational small molecule in Phase 2 clinical development. The drug is being evaluated in a completed clinical trial that enrolled 20 female participants aged 16 years and older in the United States.

Who makes ICI 182,780?

ICI 182,780 is being developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker symbol AZN. The drug is currently in Phase 2 clinical development for Systemic Lupus Erythematosus.

What phase is ICI 182,780 in?

ICI 182,780 is in Phase 2 clinical development. It is an investigational drug being studied for Systemic Lupus Erythematosus. The drug has completed one Phase 2 clinical trial, and it is not yet approved for any use.

What clinical trials is ICI 182,780 in?

ICI 182,780 has been studied in a completed Phase 2 clinical trial registered as NCT00417430. The trial, titled 'Efficacy of Faslodex in Treatment of SLE Clinical, Serologic, and Molecular Studies,' enrolled 20 participants with Systemic Lupus Erythematosus in the United States.

Is ICI 182,780 the same as Faslodex?

ICI 182,780 is also known as Faslodex. The completed clinical trial NCT00417430 for Systemic Lupus Erythematosus refers to the drug as Faslodex. This alternative name is used in the context of the clinical study.