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HIV-1 Peptide Vaccine, Microparticulate Monovalent

Phase 1

HIV Infections | Monoclonal antibody | Infectious Disease |United Therapeutics Corporation|Last Updated: Jun 24, 2005

Success Probability

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Market & Valuation

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Trial Design

Double-BlindUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

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Clinical trial landscape

HIV-1 Peptide Vaccine, Microparticulate Monovalent · 1 trial · 1 indication

Phase 1 1
NCT00002428A Phase I/II Safety and Immunogenicity Trial of UBI Microparticulate Monovalent (HIV-1 MN) Branched Peptide Vaccine in HIV-1 Seronegative Human SubjectsHIV Infections
COMPLETED- Analytics
PHASE1COMPLETED
A Phase I/II Safety and Immunogenicity Trial of UBI Microparticulate Monovalent (HIV-1 MN) Branched Peptide Vaccine in HIV-1 Seronegative Human Subjects
HIV InfectionsUnlock trial analytics

Study Design & Arms

MaskingDOUBLE
PurposePREVENTION

Interventions

NameTypeDescription
HIV-1 Peptide Vaccine, Microparticulate MonovalentBIOLOGICAL -
rgp120/HIV-1MN Monovalent Octameric V3 Peptide VaccineBIOLOGICAL -
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Eligibility Criteria

Age Range18 Years to 50 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria Volunteers must have: * Normal history and physical exam. * HIV negativity. * CD4 count \>= 400 cells/mm3. * Intermediate or high risk sexual behavior or a history of injection drug use within 12 months prior to study entry. * Normal urine dipstick with esterase and nitrite. Ex...

Countries:United States
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Frequently asked questions about HIV-1 Peptide Vaccine, Microparticulate Monovalent

What is HIV-1 Peptide Vaccine, Microparticulate Monovalent used for?

HIV-1 Peptide Vaccine, Microparticulate Monovalent is an investigational vaccine being studied for the prevention of HIV infections. It is designed for HIV-1 seronegative individuals, meaning those who do not have HIV. The vaccine is currently in clinical development and has not been approved by regulatory authorities.

Who makes HIV-1 Peptide Vaccine, Microparticulate Monovalent?

HIV-1 Peptide Vaccine, Microparticulate Monovalent is being developed by United Therapeutics Corporation, a company traded on the NASDAQ under the ticker symbol UTHR. The vaccine is in Phase 1 clinical development for HIV infections.

What phase is HIV-1 Peptide Vaccine, Microparticulate Monovalent in?

HIV-1 Peptide Vaccine, Microparticulate Monovalent is in Phase 1 clinical development. It is an investigational vaccine and has not been approved by the FDA. The vaccine is being studied for its safety and immunogenicity in HIV-1 seronegative subjects.

What clinical trials is HIV-1 Peptide Vaccine, Microparticulate Monovalent in?

HIV-1 Peptide Vaccine, Microparticulate Monovalent has one completed clinical trial, identified as NCT00002428. This was a Phase I/II safety and immunogenicity trial of the UBI Microparticulate Monovalent (HIV-1 MN) Branched Peptide Vaccine in HIV-1 seronegative human subjects, conducted in the United States.

Is HIV-1 Peptide Vaccine, Microparticulate Monovalent a monoclonal antibody?

HIV-1 Peptide Vaccine, Microparticulate Monovalent is classified as a monoclonal antibody modality, though it is a vaccine designed to elicit an immune response against HIV-1. It is being developed as a preventive vaccine for HIV infections and is currently in Phase 1 clinical trials.