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NBI-5788

Phase 2

Multiple Sclerosis | Small molecule | Immunology |Neurocrine Biosciences, Inc.|Last Updated: Mar 21, 2008

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment150
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00079495Evaluation of an Altered Peptide Ligand (NBI-5788) in Patients With Relapsing Multiple Sclerosis (MS)PHASE2 COMPLETED 150Jul 1, 2003Apr 1, 2005Mar 21, 2008 -
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
NBI-5788DRUG -
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Eligibility Criteria
Age Range18 Years — 55 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Male or female, 18 to 55 years of age * Diagnosed with relapsing multiple sclerosis, with at least one relapse in the last two years * Females must not plan on becoming pregnant * Females must either be post-menopausal, surgically incapable of bearing children, or practicing a...

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