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BSF 208075

Phase 2

Pulmonary Hypertension | Small molecule | Cardiovascular |Gilead Sciences, Inc.|Last Updated: Apr 16, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

BSF 208075 · 1 trial · 1 indication

Phase 2 1
NCT00046319Study of BSF 208075 Evaluating Exercise Capacity in Patients With Pulmonary Arterial HypertensionPulmonary Hypertension
COMPLETED60 Analytics
PHASE2COMPLETED
Study of BSF 208075 Evaluating Exercise Capacity in Patients With Pulmonary Arterial Hypertension
Pulmonary HypertensionUnlock trial analytics

Study Endpoints

Primary Endpoints

Change from baseline to Week 12 in six minute walk distance

Secondary Endpoints

Change from baseline to Week 12 in:
Borg Dyspnea Index
WHO Functional Classification
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
BSF 208075DRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites21

--Disease Characteristics-- * Current diagnosis of either PPH or PAH secondary to the scleroderma spectrum of disease (e.g., mixed connective tissue disease, systemic lupus erythematosus, systemic sclerosis, or overlap syndrome), anorexigen use, or human immunodeficiency virus (HIV) infection at th...

Countries:United StatesAustraliaBelgiumFranceGermanyItaly
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Frequently asked questions about BSF 208075

What is BSF 208075 used for?

BSF 208075 is an investigational small molecule being studied for the treatment of pulmonary hypertension, specifically pulmonary arterial hypertension. It is being developed by Gilead Sciences, Inc. (NASDAQ: GILD) and is currently in Phase 2 clinical development.

What does BSF 208075 target?

BSF 208075 is a small molecule being developed for pulmonary hypertension. Its specific molecular target has not been disclosed in available clinical trial information. The drug is being evaluated for its effects on exercise capacity in patients with pulmonary arterial hypertension.

Who makes BSF 208075?

BSF 208075 is being developed by Gilead Sciences, Inc., a biopharmaceutical company traded on NASDAQ under the ticker symbol GILD. The drug is currently in Phase 2 clinical development for the treatment of pulmonary hypertension.

What phase is BSF 208075 in?

BSF 208075 is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. A Phase 2 clinical trial evaluating the drug in patients with pulmonary arterial hypertension has been completed.

What clinical trials is BSF 208075 in?

BSF 208075 has been studied in one completed Phase 2 clinical trial, identified as NCT00046319. This trial evaluated exercise capacity in 60 patients with pulmonary arterial hypertension and was conducted in the United States, Australia, Belgium, France, Germany, and Italy.

Is BSF 208075 the same as ambrisentan?

BSF 208075 is the investigational name for the drug also known as ambrisentan. It is being developed by Gilead Sciences for the treatment of pulmonary arterial hypertension. The drug is a small molecule and has completed a Phase 2 clinical trial.