Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT02371291 | Memory Flexibility Training for Depression | PHASE1 | COMPLETED | 60 | — | — | Jan 1, 2015 | Jan 1, 2017 | Sep 11, 2017 | 2 | United Kingdom |
Self report measure of depression symptoms
| Arm | Type | Description |
|---|---|---|
| Memory Flexibility Training | EXPERIMENTAL | The MemFlex programme draws on cognitive bias modification and memory specificity training techniques (Raes et al., 2009; Dalgleish et al., 2014), and was developed by clinical psychologists. MemFlex is primarily self-guided and aims to reduce autobiographical memory biases associated with depression. The training material is presented over one face-to-face session and eight self-guided sessions. In the initial session, the researcher introduces cued-recall tasks which are used throughout the workbook, and guides the participant in completion of these tasks. When understanding of the basic principles is satisfactory, the researcher assists the participant to set a schedule for completion of the workbook over the following four weeks. The participant will receive weekly emails during this period, encouraging them to complete the workbook. They will also receive a phone call from a team member at the beginning of week three to check progress. |
| Psychoeducation | PLACEBO_COMPARATOR | The psychoeducation condition will also complete an initial face-to-face session. This session will cover the symptoms and causes of depression, and the workbook will be introduced. As in the MemFlex condition, the workbook will consist of eight self-guided sessions that the individual will be required to complete over four weeks. The participant will receive weekly emails during this period, encouraging them to complete the workbook. They will also receive a phone call from a team member at the beginning of week three to check progress, and clarify any difficulties with the workbook material. The workbook content will cover the presentation of depression and basic information on factors associated with depression, such as worry, procrastination, and sleep difficulties. Each session consists of information on psychological theories of the topic, followed by a series of questions about the material to ensure participant engagement. The workbook was developed by clinical psychologists. |
| Name | Type | Description |
|---|---|---|
| Memory Flexibility Training | BEHAVIORAL | As in experimental arm description. |
| Psychoeducation | BEHAVIORAL | As in experimental arm description. |
Inclusion Criteria: * Currently experiencing Major Depressive Episode, indexed on the Structured Clinical Interview for the DSM-IV (SCID; First et al., 1996). * Score of 13 or above on the Beck Depression Inventory (Beck et al., 1996) Exclusion Criteria: * SCID assessment indicates they are exper...