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Cognition Therapeutics, Inc.

CGTX
Fair ValueBiotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$0.89
▼ 0 · -0.16%

Financials

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52W LOW $0.5552W HIGH $2.05
Volume
78.04 K
Value Traded
1.09 M
Short % Float
8.86%
-3.23%Week
-9.58%1 Month
-17.87%3 Month
-1.04%6 Month
-89.63%5 Year
-89.63%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
84.99 M
EPS (TTM)
-0.18
P/E Ratio
-
Ent. Value
51.12 M
Total Shares
95.09 M
Float Shares
87.38 M
Insiders
8.11%
Institutions
17.44%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2 topline data readout
zervimesine
Mild cognitive impairment (MCI) and early Alzheimer's disease
Phase 2Small MoleculesNervous System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

CGTX Catalyst Timeline

Dated clinical, regulatory and corporate events for Cognition Therapeutics, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Cognition Therapeutics, Inc.

225Total events
10Upcoming
39Tier-1 (high impact)
2021 to 2027Coverage

Upcoming catalysts 2

T3Type C Meeting
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CT1812
T1Topline Readout
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CT1812

Event history 50

◆Oral PresentationPresentation
Fireside chat at B. Riley Mind, Muscle & Vision Summit
◆Oral PresentationCT1812Presentation
Presentation of additional analyses from Phase 2 SHIMMER study at AAIC
dementia with Lewy bodies (DLB)source ↗
▲FDA Feedback ReceivedCT1812FDA Meeting
FDA agreed DLB psychosis could be approvable outcome and aligned on key aspects of pivotal trial design
dementia with Lewy bodies (DLB) psychosissource ↗
▲Patent GrantedCT1812IP / Competition
Notice of Allowance for composition of matter patent covering polymorphic crystalline form of zervimesine
◆Oral PresentationPresentation
Presentation at H.C. Wainwright 7th Annual Neuro Perspectives Expert Summit
◆Oral PresentationPresentation
Presentation at 2026 Jefferies Global Healthcare Conference
◆Oral PresentationPresentation
Jefferies Global Healthcare Conference presentation
◆Timing GuidanceCT1812Presentation
FDA formal minutes expected in June 2026
dementia with Lewy bodies with psychosissource ↗
▲FDA Feedback ReceivedCT1812FDA Meeting
FDA meeting minutes received providing alignment on key aspects of pivotal trial design including psychosis as primary outcome
dementia with Lewy bodies (DLB)source ↗
▲FDA Feedback ReceivedCT1812FDA Meeting
FDA meeting to discuss Phase 2 results and registrational path for zervimesine in DLB psychosis
dementia with Lewy bodies with psychosissource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How CGTX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-07-31zervimesine (CT1812) Phase 2 data readout Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D38 / 100
Pipeline Score
$131M
Pipeline Value
Fair Value
Valuation Signal
2
Drugs Scored
1.5x
rNPV / MCap
Top 44%
Micro Cap
(rank 290 of 658)
Percentile Rank
Cognition Therapeutics, Inc. faces pipeline headwinds (38/100), with $524M risk-adjusted pipeline value, led by CT1812 in Early Alzheimer's Disease (Phase 2).
Showing 1 of 2 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
CT1812 Small moleculeNCT05531656Early Alzheimer's DiseasePhase 2 ACTIVE NOT_RECRUITING 540May 31, 2027
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Clinical Trial Results

Readouts, endpoints and source filings for every CGTX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
zervimesine dementia with Lewy bodies (DLB), mild-to-moderate Alzheimer’s diseasePhase 22026-06-01strong efficacy signals observedRead MoreCognition Therapeutics Participating in Upcoming Investor ConferencesRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Doyle John BrendanOfficer (Chief Financial Officer)Disposition -8,567 618,942 held$1.28 05/01/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
TANG CAPITAL MANAGEMENT LLC 0.1 % 1.62 M 1.20 M
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Shares held by hedge funds each quarter, and who bought or sold.

CGTX Institutional Ownership Trends

Options Data

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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

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Competitive positioning

How CGTX ranks across every disease it competes in

Competitive Position is a premium feature
See how CGTX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CGTX News

CGTX
Sep 29, 2026
CGTXPhases

Cognition Therapeutics Schedules a Type C Meeting with FDA to Align on Endpoints for Phase 3 Trial of Zervimesine (CT1812) in DLB

Cognition Therapeutics has scheduled a Type C meeting with the FDA to discuss endpoints for its Phase 3 trial of zervimesine (CT1812) in patients with dementia with Lewy bodies (DLB). The meeting, set for October 20, 2026, will focus on aligning on the primary outcome related to psychosis symptoms. Zervimesine has previously demonstrated efficacy in reducing hallucinations and delusions in DLB patients.

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CGTX
Sep 8, 2026
CGTXConferences/Events

Cognition Therapeutics to Present at H.C. Wainwright Global Investment Conference

Cognition Therapeutics, Inc. announced that CEO Lisa Ricciardi will present at the H.C. Wainwright Global Investment Conference on September 15, 2026. She will discuss the development of zervimesine, an investigational therapy for Alzheimer's disease and dementia with Lewy bodies. The presentation will be available via live webcast and later as a replay.

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CGTX
Aug 6, 2026
CGTXGeneral

Cognition Therapeutics Reports Financial Results for the Second Quarter 2026 and Provides Business Update

Cognition Therapeutics reported its financial results for Q2 2026, highlighting significant progress in its clinical programs. The company is preparing to initiate a Phase 3 trial for zervimesine targeting dementia with Lewy bodies psychosis in mid-2027. Additionally, a new patent for zervimesine enhances its intellectual property position. Despite a net loss, the company has sufficient funding to sustain operations into 2027.

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CGTX
Jul 13, 2026
CGTXConferences/Events
▼ -6.4%on this news

Cognition Therapeutics Participating in Fireside Chat at B. Riley Securities' Mind, Muscle & Vision Summit

Cognition Therapeutics, Inc. will participate in a fireside chat at the B. Riley Mind, Muscle & Vision Summit on July 16, 2026. CEO Lisa Ricciardi will discuss the ongoing START study and the upcoming Phase 3 study of zervimesine (CT1812) for dementia with Lewy bodies psychosis. The event will be recorded and available on their website.

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CGTX
Jun 24, 2026
CGTXFDA Updates
▼ -38.2%on this news

Cognition Therapeutics Aligns on Key Aspects of Pivotal Study for Zervimesine (CT1812) in DLB Psychosis Following Receipt of FDA Meeting Minutes

Cognition Therapeutics announced alignment with the FDA on key aspects of a pivotal trial for zervimesine (CT1812) targeting psychosis in dementia with Lewy bodies (DLB). The FDA considers DLB psychosis an approvable outcome, and the trial is set to begin in mid-2027. Zervimesine previously demonstrated significant improvements in psychosis symptoms during Phase 2 trials.

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CGTX
Jun 16, 2026
CGTXGeneral

Cognition Therapeutics Announces New Composition of Matter Patent, Extending Patent Protection for Lead Candidate, Zervimesine (CT1812) Through 2045

Cognition Therapeutics has announced the receipt of a Notice of Allowance from the USPTO for a new patent covering a polymorphic crystalline form of its lead candidate, zervimesine (CT1812). This patent will protect the formulation until 2045, with a possible extension to 2050. The new form is expected to enhance the drug's stability and efficacy in treating neurodegenerative disorders.

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CGTX
Jun 4, 2026
CGTXConferences/Events

https://cogrx.com COGNITION THERAPEUTICS NASDAQ: CGTX An Investigational Oral Therapy Advancing Toward Registrational Development June 2026 Jefferies Global Healthcare Conference Zervimesine in DLB Psychosis 2 COGNITION

Cognition Therapeutics (CGTX) is focusing on the development of Zervimesine, an investigational oral therapy aimed at treating dementia with Lewy bodies (DLB) psychosis. The therapy has shown promising clinical results by providing significant benefits across multiple neuropsychological domains. As the company prepares for registrational development, they face various uncertainties and risks related to future trial outcomes and market competition.

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CGTX
Jun 1, 2026
CGTXConferences/Events
▲ +5.9%on this newsshared move

Cognition Therapeutics Participating in Upcoming Investor Conferences

Cognition Therapeutics, Inc. announced that CEO Lisa Ricciardi will present at two upcoming investor conferences in June. The presentations will focus on the company's plans for a registration program in dementia with Lewy bodies (DLB) psychosis. Webcasts of the events will be available on the company's website.

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CGTX
May 21, 2026
CGTXFDA Updates

Cognition Therapeutics Completes Meeting with FDA for Zervimesine (CT1812) in Dementia with Lewy Bodies with Psychosis

Cognition Therapeutics has completed a meeting with the FDA to discuss its investigational drug zervimesine (CT1812) for treating dementia with Lewy bodies (DLB) and psychosis. During this meeting, the company reviewed data from its Phase 2 clinical study and outlined plans for a registrational program. The FDA's feedback was described as positive, marking progress in addressing DLB psychosis. CEO Lisa Ricciardi expressed optimism about moving forward following a formal review of the meeting notes expected in June.

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CGTX
May 14, 2026
CGTXFDA Updates

Cognition Therapeutics Receives Second Philanthropic Donation to Extend Ongoing Expanded Access Program for Zervimesine (CT1812) in Dementia with Lewy Bodies

Cognition Therapeutics has received a second philanthropic donation to extend its expanded access program for zervimesine, an investigational therapy for dementia with Lewy bodies. This program, which has enrolled 32 participants, will provide two years of treatment. The company is also preparing to meet with the FDA to discuss future clinical trials for zervimesine.

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CGTX
May 7, 2026
CGTXFDA Updates
▼ -5.7%on this newsshared move

Cognition Therapeutics Reports Financial Results for the First Quarter 2026

Cognition Therapeutics (CGTX) reported its financial results for Q1 2026 and announced a scheduled meeting with the FDA's Division of Psychiatry for May 20, 2026, to discuss registrational plans for zervimesine in treating dementia with Lewy body psychosis. The company anticipates topline results from a Phase 2 study in early Alzheimer's disease by 2027, which may guide further clinical development. Additionally, Cognition indicated that it has sufficient cash reserves to support its operations and capital expenditures through mid-2027, though it continues to operate at a loss.

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CGTX
Apr 14, 2026
CGTXGeneral

Cognition Therapeutics Targets Faster DLB Psychosis Path as Zervimesine Nears Late-Stage Plans

Cognition Therapeutics is focusing on a faster approach to address psychosis in dementia with Lewy bodies (DLB) as it prepares for late-stage plans with Zervimesine. The article does not provide specific details about the drug's efficacy or timeline for the upcoming stages.

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CGTX
Apr 7, 2026
CGTXConferences/Events

Cognition Therapeutics to Present at Needham Virtual Healthcare Conference

Cognition Therapeutics, Inc. will present at the Needham Virtual Healthcare Conference on April 13, 2026. CEO Lisa Ricciardi will discuss the company's progress in developing treatments for Alzheimer's disease and dementia with Lewy bodies. The presentation will be available via live webcast and archived for 90 days. Cognition's lead candidate, zervimesine, has shown promise in Phase 2 trials.

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CGTX
Apr 1, 2026
CGTXPhases
▲ +17.4%on this newsshared move

Cognition Therapeutics CEO Issues Letter to Shareholders

Cognition Therapeutics' CEO Lisa Ricciardi shared a letter highlighting the company's advancements in developing zervimesine (CT1812) for dementia with Lewy bodies psychosis and Alzheimer's disease. The Phase 2 START trial is fully funded and expected to read out in late 2027. Positive results from previous trials support the ongoing development of zervimesine, with plans for future discussions with the FDA.

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CGTX
Mar 26, 2026
CGTXGeneral

Cognition Therapeutics Reports Year End 2025 Financial Results and Provides Clinical Development Update

Cognition Therapeutics reported its financial results for 2025 and provided updates on its clinical development plans for zervimesine, particularly targeting dementia with Lewy bodies (DLB) psychosis. The company aims to meet with the FDA Division of Psychiatry in mid-2026 to discuss its registrational plan. Additionally, enrollment in the Phase 2 START trial for early Alzheimer's disease has been completed, with results expected in 2027.

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CGTX
Mar 23, 2026
CGTXConferences/Events
▲ +5.6%on this newsshared move

Cognition Therapeutics to Report Fourth Quarter and Year End 2025 Financial Results

Cognition Therapeutics plans to release its financial results for Q4 and the full year 2025 on March 26, 2026. A conference call will follow to discuss these results and provide a business update. The company focuses on developing therapies for neurodegenerative disorders, with its lead candidate zervimesine showing promise in clinical trials.

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CGTX
Mar 17, 2026
CGTXConferences/Events
▲ +6.5%on this news

Cognition Therapeutics Presents Evidence of Zervimesine’s Impact on Neuropsychiatric Symptoms of Dementia with Lewy Bodies at AD/PD 2026

Cognition Therapeutics presented findings from the Phase 2 SHIMMER study on zervimesine at the AD/PD 2026 conference. The analysis highlighted zervimesine's effectiveness in slowing the decline of neuropsychiatric symptoms in dementia with Lewy bodies (DLB). The treatment showed promise for patients who cannot tolerate traditional antipsychotics, addressing a critical need in DLB care.

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CGTX
Mar 2, 2026
CGTXPhases

Cognition Therapeutics Advancing Zervimesine (CT1812) for Dementia with Lewy Bodies (DLB) Psychosis

Cognition Therapeutics is advancing zervimesine (CT1812) for treating dementia with Lewy bodies (DLB) psychosis, following positive Phase 2 SHIMMER study results. The company plans to pursue a registrational path with the FDA, addressing a critical need as no approved treatments currently exist for DLB psychosis. Zervimesine has shown potential benefits without impairing motor function.

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CGTX
Feb 5, 2026
CGTXFDA Updates

Cognition Therapeutics Extends Expanded Access Program for Zervimesine (CT1812) in Dementia with Lewy Bodies

Cognition Therapeutics has extended its expanded access program for zervimesine (CT1812) in dementia with Lewy bodies, allowing for additional months of treatment. The program, which started in June 2025, has received positive feedback from participants regarding its operational aspects. The company aims to gather more long-term safety data while facilitating local monitoring by physicians. Zervimesine remains investigational and has not yet received regulatory approval.

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CGTX
Jan 27, 2026
CGTXFDA Updates

Cognition Therapeutics Completes Type C Meeting with FDA for Zervimesine (CT1812) in Dementia with Lewy Bodies

Cognition Therapeutics held a Type C meeting with the FDA to discuss the Phase 2b study of zervimesine for dementia with Lewy bodies. The meeting focused on establishing clinically meaningful endpoints for the study. The company anticipates receiving the meeting minutes soon and aims to continue collaboration with the FDA. Zervimesine is an investigational drug that targets neurodegenerative disorders.

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About Cognition Therapeutics, Inc.

Purchase, NY 14 employees cogrx.com
Headquarters2500 WESTCHESTER AVE, PURCHASE, NY, 10577
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