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COMPASS Pathways Plc - American Depository Shares

CMPSFDA catalysts, PDUFA dates & pipeline intelligence
$11.5
▼ -0.06 · -0.52%

Financials

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Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
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Shares Out.
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Quarterly Cash
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52W LOW $4.8852W HIGH $15.87
Volume
97.36 K
Value Traded
24.10 M
Short % Float
12.97%
Days to Cover
6.8
+4.71%Week
-0.26%1 Month
+2.84%3 Month
+21.53%6 Month
-67.01%5 Year
-49.53%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
1.60 B
EPS (TTM)
-2.85
P/E Ratio
-
Ent. Value
1.22 B
Total Shares
138.48 M
Float Shares
136.24 M
Insiders
1.61%
Institutions
66.05%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 data presentation
COMP360 psilocybin
Treatment-Resistant Depression (TRD)
Breakthrough
Phase 3PeptidesPsychiatric Disorders
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

CMPS Catalyst Timeline

Dated clinical, regulatory and corporate events for COMPASS Pathways Plc - American Depository Shares

Catalyst Timeline

Dated clinical, regulatory & corporate events for COMPASS Pathways Plc - American Depository Shares

100Total events
13Upcoming
24Tier-1 (high impact)
2020 to 2028Coverage

Upcoming catalysts 2

T1NDA Submission
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COMP360
T2Quarterly Update
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Event history 50

●Equity OfferingCorporate
Equity awards granted to ten newly hired non-executive employees
●Management ChangeCorporate
Kelley Boucher appointed Chief People Officer, effective today
●Equity OfferingCorporate
Equity awards granted to senior leader under 2026 Inducement Plan
●Timing GuidancePresentation
Compass Pathways launches 'Change the Tune in TRD' U.S. HCP disease education initiative
treatment-resistant depressionsource ↗
▲Grant / FundingCOMP360Corporate
Strata Mental Health Solutions awarded one of five U.S. HCP training grants from Compass Pathways for COMP360 provider training
▲Grant / FundingCOMP360Corporate
Fluence selected by Compass Pathways as recipient of U.S. healthcare provider training grant program
treatment-resistant depressionsource ↗
▲Topline ReadoutCOMP360Clinical Data
Topline 52-week (Part C) results from Phase 3 COMP005 trial of COMP360 in TRD
treatment-resistant depression (TRD)source ↗
▲Long Term DataCOMP360Clinical Data
52-week durability data from Phase 3 COMP005 Part C demonstrating benefit extended out to 1 year
treatment-resistant depression (TRD)source ↗
▲Safety Data UpdateCOMP360Clinical Data
COMP360 safety profile in Part C consistent with Parts A and B, no new safety findings
treatment-resistant depression (TRD)source ↗
●R&D DayPresentation
Compass Pathways to participate in 2026 Cantor Global Healthcare Conference
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How CMPS actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-07-07COMP360 (synthetic, proprietary formulation of psilocybin) Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Top 28%
Micro Cap
(rank 189 of 674)
Percentile Rank
Showing 5 of 6 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
COMP360 Small moleculeNCT05711940Treatment Resistant DepressionPhase 3 ACTIVE NOT_RECRUITING 1,082Dec 1, 2026
COMP360 Small moleculeNCT05733546Major Depressive DisorderPhase 2 ACTIVE NOT_RECRUITING 122Sep 1, 2025
COMP360 psilocybin Small moleculeNCT07570654PTSD - Post Traumatic Stress DisorderPhase 2/3 RECRUITING 300Sep 1, 2029
COMP360 Small moleculeCompletedNCT05312151Post Traumatic Stress DisorderPhase 2 COMPLETED 22Feb 12, 2024
COMP360 Small moleculeCompletedNCT05481736Anorexia NervosaPhase 2 COMPLETED 48Nov 18, 2024
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every CMPS program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
COMP360
Breakthrough
treatment-resistant depressionPhase 32026-09-0952-week resultsRead MoreCompass Pathways’ New 52-Week Topline Open-Label Data from Phase 3 COMP005 Trial Demonstrates Additional Benefit from Another COMP360 Dose in Part C Extending Durability Out to 1 YearRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Karydas DaphneDirectorGrant/Award 21,110 21,110 held$0.00 05/27/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Deep Track Capital, LP 2.5 % (127.3 %) 172.09 M 12.16 M
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

CMPS Short Interest

Shares sold short, counted twice a month.

12.97%
Short % of Float
of tradable shares sold short
17.7M
Shares Sold Short
+3.7% vs prior count
6.8 High
Days to Cover
trading days of normal volume to buy every short share back
2.6M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How CMPS ranks across every disease it competes in

Competitive Position is a premium feature
See how CMPS ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CMPS News

CMPS
Nov 2, 2026
CMPSGeneral
▼ -0.5%today

New Joint Survey from Compass Pathways and the Depression and Bipolar Support Alliance Reveals the Lived Burden of Treatment-Resistant Depression on Patients and Caregivers

Compass Pathways and the Depression and Bipolar Support Alliance released a report detailing the impact of treatment-resistant depression (TRD) on patients and caregivers. The national survey included responses from 261 individuals with TRD and 73 caregivers, highlighting the significant daily challenges faced by those affected. The findings aim to inform better treatment options in mental health care.

Read more →
CMPS
Oct 28, 2026
CMPSConferences/Events

Compass Pathways to Highlight Scientific Research and TRD Disease State Education Efforts at the 2026 Neuroscience Education Institute Fall Congress

Compass Pathways will participate in the 2026 Neuroscience Education Institute Fall Congress, focusing on treatment-resistant depression (TRD). The company will present its educational campaign, 'Change the Tune in TRD,' and encore presentations from its COMP360 psilocybin clinical program. This event aims to enhance understanding among U.S. healthcare professionals.

Read more →
CMPS
Oct 27, 2026
CMPSGeneral
▲ +6.9%on this newsshared move

Compass Pathways to Announce Third Quarter 2026 Financial Results on November 3, 2026

Compass Pathways plc will announce its third quarter 2026 financial results on November 3, 2026. The company will also provide updates on recent developments during a conference call at 8:00 am ET. Compass is focused on developing COMP360 psilocybin for treatment-resistant depression and PTSD, with significant designations from regulatory bodies.

Read more →
CMPS
Oct 14, 2026
CMPSGeneral

Compass Pathways Joins Forces with Leading Mental Health Organizations to Mark First-Ever U.S. Treatment-Resistant Depression (TRD) Awareness Day

Compass Pathways has announced the first-ever Treatment-Resistant Depression (TRD) Awareness Day in the U.S., aimed at raising awareness about the condition and its impact on patients and caregivers. The initiative is supported by major mental health organizations and seeks to foster understanding and support for those affected by TRD. A report detailing the burden of TRD will be released in the future.

Read more →
CMPS
Oct 5, 2026
CMPSGeneral

Compass Pathways Celebrates Opening of New U.S. Office in Jersey City, New Jersey

Compass Pathways has inaugurated its new U.S. office in Jersey City, New Jersey, which will serve as a hub for its employees in the tri-state area. This 6,327-square-foot facility aims to support the company's efforts in advancing its investigational treatment, COMP360, for treatment-resistant depression. The CEO highlighted the importance of this milestone in the company's growth and commitment to improving mental health care.

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CMPS
Oct 2, 2026
CMPSGeneral

Compass Pathways Announces New Employee Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Compass Pathways plc has announced the granting of equity awards to a senior leader and ten new non-executive employees under its 2026 Inducement Plan. This move reflects the company's strategy to enhance its leadership and workforce as it focuses on developing new treatment options in mental health care. The equity awards for the senior leader include options to purchase a total of 121,800 shares.

Read more →
CMPS
Sep 30, 2026
CMPSGeneral

Compass Pathways Appoints Kelley Boucher as Chief People Officer

Compass Pathways has appointed Kelley Boucher as Chief People Officer, effective immediately. This strategic move aims to strengthen the executive team as the company focuses on scaling its operations. The appointment aligns with Compass's mission to introduce innovative psychedelic treatments in psychiatry.

Read more →
CMPS
Sep 16, 2026
CMPSConferences/Events

Compass Pathways to Participate in TD Cowen 6th Annual Novel Mechanisms in Neuropsychiatry Summit on September 23, 2026

Compass Pathways plc will participate in the TD Cowen 6th Annual Novel Mechanisms in Neuropsychiatry Summit on September 23, 2026. The company will host a fireside chat at 1:00 pm ET, which will be available via a live audio webcast. Compass is focused on developing innovative treatments for mental health, including its investigational psilocybin treatment, COMP360.

Read more →
CMPS
Sep 15, 2026
CMPSGeneral
▼ -5%on this newsshared move

Compass Pathways Launches ‘Change the Tune in TRD’ in the U.S. to Advance HCP Understanding of Treatment-Resistant Depression at Psych Congress 2026

Compass Pathways has launched the 'Change the Tune in TRD' initiative aimed at enhancing healthcare provider understanding of treatment-resistant depression (TRD). This campaign will delve into the neurobiology of TRD and assist in navigating care pathways for both patients and providers. The initiative was announced during the Psych Congress 2026.

Read more →
CMPS
Sep 11, 2026
CMPSGeneral

Strata Mental Health Solutions Awarded U.S. Healthcare Provider Training Grant from Compass Pathways to Develop Provider Training for COMP360

Strata Mental Health Solutions has received a grant from Compass Pathways to develop training programs for healthcare providers regarding COMP360, an investigational psilocybin treatment. This initiative aims to prepare clinical networks for the potential delivery of psychedelic treatments. The collaboration highlights Strata's expertise in the field.

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CMPS
Sep 10, 2026
CMPSGeneral
▼ -6.3%on this newsshared move

Fluence Selected by Compass Pathways to Develop Post-Approval COMP360 Provider Training

Fluence has been selected by Compass Pathways to develop a certificate program for healthcare providers in anticipation of the FDA's approval of COMP360, a psilocybin treatment for depression. The program will consist of three modules aimed at equipping clinicians with the necessary skills and knowledge to support patients. This collaboration emphasizes Fluence's dedication to translating research into clinical practice.

Read more →
CMPS
Sep 10, 2026
CMPSGeneral
▼ -6.3%on this newsshared move

Compass Pathways Announces U.S. Grant Program Recipients for the Development of Post-Approval COMP360 Provider Training

Compass Pathways has announced the recipients of its U.S. grant program aimed at developing training for healthcare providers to deliver COMP360, a psilocybin treatment for treatment-resistant depression. The program awarded grants to five organizations, expanding from the initial plan of three due to high-quality applicants. This initiative is part of Compass's commitment to ensuring effective treatment delivery upon COMP360's potential approval.

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CMPS
Sep 10, 2026
CMPSConferences/Events
▼ -6.3%on this newsshared move

Compass Pathways to Participate in Investor Conferences the Week of September 14th

Compass Pathways plc will participate in investor conferences during the week of September 14th. The company aims to engage with investors at the H.C. Wainwright Annual Global Investment Conference and the Morgan Stanley 24th Annual Global Healthcare Conference. These events will provide a platform for discussing their innovative approaches in mental health care.

Read more →
CMPS
Sep 9, 2026
CMPSPhases
▲ +8%on this newsshared move

Compass Pathways’ New 52-Week Topline Open-Label Data from Phase 3 COMP005 Trial Demonstrates Additional Benefit from Another COMP360 Dose in Part C Extending Durability Out to 1 Year

Compass Pathways has released topline results from the Phase 3 COMP005 trial of COMP360, a psilocybin formulation for treatment-resistant depression. The open-label Part C data indicates an additional benefit from another dose, extending the treatment's durability to one year. This supports the drug's differentiated profile and potential for long-term effectiveness.

Read more →
CMPS
Sep 8, 2026
CMPSConferences/Events
▲ +5.8%on this newsshared move

Compass Pathways to Debut U.S. HCP Education Campaign and Present New HEOR Data at Psych Congress 2026

Compass Pathways is set to launch its 'Change the Tune in TRD' education campaign at Psych Congress 2026, focusing on treatment-resistant depression (TRD). The company will also present new health economics and outcomes research data, alongside findings from its COMP360 psilocybin clinical trials. This initiative aims to enhance healthcare provider education on TRD.

Read more →
CMPS
Sep 2, 2026
CMPSGeneral

Compass Pathways Recognized as a 2026 Fierce 50 Breakthrough Honoree

Compass Pathways has been honored as a 2026 Fierce 50 Breakthrough honoree, highlighting its commitment to advancing treatment options in mental health care. This recognition by Fierce Pharma, Fierce Biotech, and Fierce Healthcare underscores the company's role in fostering innovation and shaping the future of biopharma. The award celebrates organizations making significant contributions to medicine.

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CMPS
Sep 1, 2026
CMPSConferences/Events

Compass Pathways to Participate in 2026 Cantor Global Healthcare Conference on September 9, 2026

Compass Pathways plc will participate in the 2026 Cantor Global Healthcare Conference on September 9, 2026. The company will host a fireside chat and join a panel discussing psychedelics in mental health treatment. This engagement underscores their commitment to exploring new therapeutic options.

Read more →
CMPS
Aug 6, 2026
CMPSConferences/Events

Compass Pathways to Participate in Canaccord Genuity's 46th Annual Growth Conference on August 12, 2026

Compass Pathways plc has announced its participation in the Canaccord Genuity's 46th Annual Growth Conference on August 12, 2026. The management will also engage in a fireside chat at 8:00 am ET. Additionally, they will attend the Stifel Biotech Summit in Newport, Rhode Island, on August 10, 2026, showcasing their commitment to investor relations.

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CMPS
Aug 6, 2026
CMPSPhases

Compass Pathways Working with U.S. Department of Veterans Affairs for Investigational Study of Psilocybin

Compass Pathways is collaborating with the U.S. Department of Veterans Affairs on a multi-site randomized controlled clinical trial. This study aims to evaluate the safety and efficacy of COMP360 psilocybin for treating treatment-resistant depression in veterans, particularly those experiencing post-traumatic stress.

Read more →

About COMPASS Pathways Plc - American Depository Shares

Chesire, X0 156 employees compasspathways.com
Headquarters3RD FLOOR, 1 ASHLEY ROAD, CHESIRE, X0, WA14 2DT
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