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BMS-986507

Phase 1

Lung Cancer | Small molecule | Oncology |Bristol-Myers Squibb Company|Last Updated: Aug 18, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedCONTROLLED
Total Trials1
Total Enrollment416

FDA Designations

No designations recorded

Clinical trial landscape

BMS-986507 · 1 trial · 2 indications

Phase 1 1
NCT06618287A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid TumorsLung Cancer
RECRUITING416 Analytics
PHASE1RECRUITING
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Lung CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of participants with adverse events (AEs)
Up to 3 years
Number of participants with serious adverse events (SAEs)
Up to 3 years
Number of participants with AEs meeting protocol defined dose-limiting toxicity (DLT) critera
Up to 3 years
Number of participants with AEs leading to discontinuation
Up to 3 years
Number of participants with AEs leading to death
Up to 3 years
Number of DLTs that occur during the DLT evaluation period
Up to 3 weeks

Secondary Endpoints

Maximum observed serum concentration (Cmax)
Up to 3 years
Time of maximum observed concentration (Tmax)
Up to 3 years
Area under the concentration-time curve from time zero to time of last quantifiable concentration (AUC(0-T))
Up to 3 years
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Group AEXPERIMENTAL -
Group BEXPERIMENTAL -
Group CEXPERIMENTAL -
Group DEXPERIMENTAL -
Group EEXPERIMENTAL -

Interventions

NameTypeDescription
BMS-986507DRUGSpecified dose on specified days
OsimertinibDRUGSpecified dose on specified days
PembrolizumabDRUGSpecified dose on specified days
NivolumabDRUGSpecified dose on specified days
PumitamigDRUGSpecified dose on specified days
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites66

Inclusion Criteria * Participants must have at least one measurable lesion per response evaluation criteria in solid tumors. * Participants must have an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1. * Participants must have a life expectancy of at least 3 months at the tim...

Countries:United StatesAustraliaCanadaChileFranceItalyNetherlandsSpainTaiwanUnited Kingdom
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Competitive Landscape -Lung Cancer 281 trials

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Recent Changes (Last 90 Days)

LOWAug 19, 2026NCT06618287lastUpdatePostDate: changed
LOWAug 19, 2026NCT06618287lastUpdatePostDate: changed
LOWAug 19, 2026NCT06618287lastUpdatePostDate: changed
LOWJul 24, 2026NCT06618287lastUpdatePostDate: changed
LOWJul 24, 2026NCT06618287lastUpdatePostDate: changed
LOWJul 2, 2026NCT06618287lastUpdatePostDate: changed
LOWJul 2, 2026NCT06618287lastUpdatePostDate: changed
LOWJul 2, 2026NCT06618287lastUpdatePostDate: changed
LOWJul 2, 2026NCT06618287lastUpdatePostDate: changed

Frequently asked questions about BMS-986507

What is BMS-986507 used for?

BMS-986507 is an investigational small molecule being developed for the treatment of lung cancer. It is currently being studied in a Phase 1 clinical trial in adult participants with advanced solid tumors, including lung cancer and breast cancer. The drug is not yet approved and is still in clinical development.

Who makes BMS-986507?

BMS-986507 is being developed by Bristol-Myers Squibb Company, a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol BMY. The company is conducting a Phase 1 clinical trial to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 in combination with other treatments.

What phase is BMS-986507 in?

BMS-986507 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The ongoing Phase 1 trial is recruiting participants and is designed to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adults with advanced solid tumors.

What clinical trials is BMS-986507 in?

BMS-986507 is being studied in a Phase 1 clinical trial with the identifier NCT06618287. This trial is recruiting 416 participants and is evaluating BMS-986507 combinations in adult participants with advanced solid tumors, including lung cancer and breast cancer. The trial is being conducted in multiple countries, including the United States, Australia, Canada, and several European countries.

Is BMS-986507 being studied in a randomized controlled trial?

Yes, the Phase 1 clinical trial of BMS-986507 is randomized and controlled. The trial is not double-blinded, but it includes a control group. The study is actively recruiting participants with advanced solid tumors, including lung cancer and breast cancer, and is being conducted at sites in the United States, Australia, Canada, Chile, France, Italy, Netherlands, Spain, Taiwan, and the United Kingdom.