Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00838877 | Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid | PHASE1 | COMPLETED | 26 | — | — | Jan 1, 2009 | Oct 1, 2009 | Oct 23, 2009 | 2 | Sweden |
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| radioligand [18F]AZD4694 | DRUG | single dose of iv. admin. 1-2 times per subject |
| radioligand [11C]AZD2184 | DRUG | single dose of iv admin. 1 time per subject |
Inclusion Criteria: * Alzheimer's Disease patients - 50-85 years, mild to moderate AD: MMSE ≥16 and ≤ 26, clinical progression of AD over 12 months. * Healthy volunteers: - 50-75 years * BMI 18 and 30 m2/kg * Clinically normal physical findings including supine blood pressure and pulse rate. Exclu...