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Voyager Therapeutics, Inc.

VYGR
Richly ValuedBiotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$2.46
▲ +0.12 · +5.06%

Financials

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52W LOW $2.3352W HIGH $5.55
Volume
262.24 K
Value Traded
1.27 M
Short % Float
7.09%
-0.61%Week
-25.08%1 Month
-29.22%3 Month
-34.89%6 Month
-5.86%5 Year
-74.83%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
151.58 M
EPS (TTM)
-1.75
P/E Ratio
-
Ent. Value
3.07 M
Total Shares
61.58 M
Float Shares
51.59 M
Insiders
16.27%
Institutions
57.15%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 1 data readout
VY7523 Anti-Tau Antibody
Alzheimer's disease
Phase 1BiologicsNervous System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

VYGR Catalyst Timeline

Dated clinical, regulatory and corporate events for Voyager Therapeutics, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Voyager Therapeutics, Inc.

569Total events
6Upcoming
81Tier-1 (high impact)
2015 to 2028Coverage

Upcoming catalysts 2

T1Topline Readout
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VY7523
T2Trial Initiation
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VY1706

Event history 50

●Quarterly UpdateCorporate
Q2 2026 financial results reported
◆Oral PresentationPresentation
Voyager CEO to participate in pre-recorded fireside chat at H.C. Wainwright 7th Annual Neuro Perspectives Hybrid Conference
▲IND ClearanceVY1706IND
FDA IND clearance for VY1706
Alzheimer's diseasesource ↗
▲Oral PresentationVY1706Presentation
Late-breaking oral presentation of 3-month GLP toxicology data for VY1706 at ASGCT 2026
Alzheimer's diseasesource ↗
◆Poster PresentationPresentation
Poster presentation on ApoE4/ApoE2 gene therapy in ApoE4 humanized mice
Alzheimer's diseasesource ↗
●Quarterly UpdateCorporate
Q1 2026 financial results reported
●IND SubmissionVY1706IND
IND application process on track for Q2 2026
Alzheimer's diseasesource ↗
◆Trial InitiationVY1706Trial
VY1706 clinical entry anticipated H2 2026
Alzheimer's diseasesource ↗
◆Topline ReadoutVY7523Clinical Data
Initial tau PET imaging data from multiple ascending dose trial
Alzheimer's diseasesource ↗
◆Trial InitiationTrial
Two I.V.-delivered neuro gene therapies to enter clinic H2 2026
neurological diseasessource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How VYGR actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-09-30VY7523 Phase 2 data readout Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D24 / 100
Pipeline Score
$18M
Pipeline Value
Richly Valued
Valuation Signal
2
Drugs Scored
0.1x
rNPV / MCap
Top 86%
Micro Cap
(rank 566 of 658)
Percentile Rank
Voyager Therapeutics, Inc. faces pipeline headwinds (24/100), with $246M risk-adjusted pipeline value, led by VY7523 in Alzheimer's Disease (AD) (Phase 1).
Showing 1 of 2 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
VY7523 Small moleculeNCT06874621Alzheimer's Disease (AD)Phase 1 ACTIVE NOT_RECRUITING 52May 1, 2027
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Clinical Trial Results

Readouts, endpoints and source filings for every VYGR program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
VY1706 Alzheimer's disease2026-05-13well tolerated; no adverse clinical pathology or histopathological findings up to the highest dose tested (5E13 vg/kg); reduced tau protein up to 64% in key brain regions of non-human primates (NHPs) at 13 weeks following a single IV dose; dose-dependent reductions of up to 51-75% MAPT mRNA; 48-64% tau protein in key brain regions at 13 weeks in NHPsRead MoreVoyager ASGCT Late Breaker: Single IV Dose of VY1706 Well Tolerated, Reduced Tau in 3-Month GLP Toxicology Data; Clinical Trial in Alzheimer’s Disease Expected H2 2026Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Sandrock AlfredDirector, Officer (President and CEO)Sell -11,511 472,549 held$3.87 04/02/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Opaleye Management Inc. 0.4 % (-33.3 %) 4.15 M 1.19 M 3.04% ( 35.00 K)
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Shares held by hedge funds each quarter, and who bought or sold.

VYGR Institutional Ownership Trends

Options Data

Option Volume

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Call OI
Put OI
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Today vs avg
Option Volume
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Put Vol
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-16
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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How VYGR ranks across every disease it competes in

Competitive Position is a premium feature
See how VYGR ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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VYGR News

VYGR
Sep 1, 2026
VYGRConferences/Events

Voyager to Present at Upcoming Investor Conferences

Voyager Therapeutics, Inc. has announced its participation in several upcoming investor conferences, including the Wells Fargo 21st Annual Healthcare Conference and the 2026 Cantor Global Healthcare Conference. The company aims to highlight its innovative approaches to treating neurological diseases. A webcast of the Wells Fargo fireside chat will be available for investors.

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VYGR
Aug 6, 2026
VYGRGeneral

Voyager Reports Second Quarter 2026 Financial and Operating Results

Voyager Therapeutics reported its second quarter 2026 financial results, highlighting the expected clinical data for VY7523 and VY1706 in Alzheimer's by Q4 2026. The company ended the quarter with a robust cash position of $149 million, providing a financial runway into 2028. This positions Voyager favorably for ongoing and future developments.

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VYGR
Jul 13, 2026
VYGRPhases
▼ -5.8%on this news

Voyager Demonstrates Single IV Dose of VY1706 Well Tolerated, Reduced Tau in 6-Month GLP Toxicology Study; Initiation of Clinical Trial in Alzheimer’s Disease Expected H2 2026

Voyager Therapeutics presented data on VY1706, showing it was well tolerated in a six-month GLP toxicology study. The study demonstrated a reduction in tau levels, which is significant for Alzheimer's disease research. The company plans to initiate a clinical trial for VY1706 in Alzheimer's disease by the second half of 2026.

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VYGR
Jun 29, 2026
VYGRConferences/Events

Voyager’s Tau-Targeted Gene Therapy VY1706 for Alzheimer’s Disease to Be Featured in Developing Topics Poster Presentation at AAIC 2026

Voyager Therapeutics announced that its investigational gene therapy VY1706 for Alzheimer's disease will be featured in a poster presentation at the Alzheimer's Association International Conference (AAIC) 2026. The therapy, which targets tau proteins, has received FDA clearance for clinical trials, with dosing expected to start in the second half of 2026. Preclinical studies show promising results in reducing tau levels and a favorable safety profile.

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VYGR
Jun 11, 2026
VYGRConferences/Events

Voyager to Present at H.C. Wainwright 7th Annual Neuro Perspectives Hybrid Conference

Voyager Therapeutics, Inc. will present at the H.C. Wainwright 7th Annual Neuro Perspectives Hybrid Conference. CEO Alfred W. Sandrock, Jr. will participate in a pre-recorded fireside chat, which will be available on-demand starting June 15, 2026. The company focuses on leveraging genetics to treat neurological diseases and has a diverse pipeline targeting various conditions.

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VYGR
Jun 1, 2026
VYGRFDA Updates

Voyager Receives FDA IND Clearance for VY1706, First Gene Therapy Approach to Reducing Tau Production in the Brain for Alzheimer’s Disease

Voyager Therapeutics announced that the FDA has approved its IND application for VY1706, a gene therapy aimed at reducing tau protein levels associated with Alzheimer's disease. The company plans to initiate a clinical trial in the second half of 2026, focusing on adults with early-stage Alzheimer's. Preclinical studies have shown substantial reductions in tau levels and a favorable safety profile, indicating potential promise for this innovative treatment approach.

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VYGR
May 13, 2026
VYGRPhases

Voyager ASGCT Late Breaker: Single IV Dose of VY1706 Well Tolerated, Reduced Tau in 3-Month GLP Toxicology Data; Clinical Trial in Alzheimer’s Disease Expected H2 2026

Voyager Therapeutics presented promising data on VY1706, a gene therapy for Alzheimer's disease, at the ASGCT 2026 Annual Meeting. The three-month GLP toxicology study showed that VY1706 was well tolerated in non-human primates and significantly reduced tau protein levels. The company is on track to submit an IND application in Q2 2026, with clinical trials expected to start in H2 2026.

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VYGR
May 8, 2026
VYGRGeneral

Voyager Reports First Quarter 2026 Financial and Operating Results

Voyager Therapeutics reported its first quarter 2026 financial results, highlighting a strong cash position of $172 million that supports operations into 2028. The company is preparing for clinical entry of its tau silencing gene therapy, VY1706, expected in the second half of 2026. Additionally, they anticipate significant data on tau knockdown as a treatment approach for Alzheimer's disease.

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VYGR
Apr 28, 2026
VYGRConferences/Events

Voyager IV-Delivered CNS Gene Therapies Featured in Multiple Presentations at ASGCT 2026, Including Late Breaker on Tau-Targeted VY1706 for Alzheimer’s Disease

Voyager Therapeutics announced multiple presentations at the ASGCT 2026 Annual Meeting, highlighting their investigational gene therapy VY1706 for Alzheimer's disease. A late-breaking presentation will showcase three-month GLP toxicology data demonstrating the therapy's pharmacology and safety. The company plans to submit an IND application in Q2 2026, aiming for first-in-human dosing later in the year.

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VYGR
Mar 13, 2026
VYGRGeneral
▼ -8.5%on this news· ran to -23% by day 3

Voyager Acquisition Corporation Announces Approval of Its Business Combination with Veraxa Biotech AG

Voyager Acquisition Corporation has obtained approval for its business combination with Veraxa Biotech AG, allowing the merger to proceed. Following the closing, the new entity is set to be listed on Nasdaq under the ticker 'VRXA'. Notably, approximately 99.67% of Voyager's Class A ordinary shares will be redeemed, leaving around $885,556 in the trust account. Veraxa specializes in developing next-generation antibody therapeutics, signifying a promising future for the combined firm.

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VYGR
Mar 11, 2026
VYGRGeneral

Voyager Acquisition Corporation Announces Redemption Results in Connection with its Business Combination with VERAXA Biotech AG

Voyager Acquisition Corporation has announced that 25,217,315 of its Class A ordinary shares were redeemed, amounting to approximately 99.67% of the total outstanding shares in relation to its business combination with VERAXA Biotech AG. Following the expected redemptions, around $885,556 will remain in the trust account, and 82,685 Class A shares will convert into shares of VERAXA Biotech Holding AG. The merger is anticipated to establish the combined entity as a publicly traded company on NASDAQ under the symbol 'VRXA.' VERAXA aims to advance a pipeline of innovative antibody-based therapeutics.

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VYGR
Mar 9, 2026
VYGRGeneral
▲ +5.4%on this news· ran to +28% by day 1shared move

Voyager Reports Fourth Quarter and Full Year 2025 Financial and Operating Results

Voyager Therapeutics has announced its fourth quarter and full year 2025 financial results, highlighting a transformative year for the company. Key developments include the anticipated clinical entry of VY1706 and expected clinical data for VY7523 in the second half of 2026. The company ended 2025 with a robust cash position that is projected to sustain operations through 2028. Furthermore, the advancement of the Voyager NeuroShuttle platform aims to enhance therapeutic delivery for neurological diseases.

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VYGR
Jan 8, 2026
VYGRGeneral

Leveraging Genetics to Treat Neurological Diseases Corporate Deck / January 2026 2 | Forward - Looking Statements This presentation contains forward - looking statements for the purposes of the safe harbor provisions und

Voyager Therapeutics has outlined its strategic focus on leveraging genetics to treat neurological diseases, particularly Alzheimer's, in its January 2026 corporate presentation. The company emphasizes the achievement of key preclinical and clinical milestones as part of its development pipeline, including the introduction of therapies targeting tau protein. Although there are optimistic financial forecasts regarding milestone payments, Voyager acknowledges various inherent risks, including regulatory uncertainties and external competition. The firm is managing a solid cash position expected to last until 2028 to support its ongoing projects.

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VYGR
Nov 10, 2025
VYGRGeneral

Transition Bio and Voyager Announce Collaboration to Advance Small Molecules Targeting TDP-43 in ALS and Frontotemporal Dementia

Transition Bio and Voyager Therapeutics have announced a collaboration to develop small molecules targeting TDP-43 for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Transition Bio will lead the discovery and optimization of these molecules, with Voyager having the option to license the program. The partnership includes an upfront payment and potential milestone payments totaling up to $500 million.

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VYGR
Nov 10, 2025
VYGRGeneral

Voyager Reports Third Quarter 2025 Financial and Operating Results

Voyager Therapeutics reported its third quarter 2025 financial results, highlighting a robust cash position of $229 million, which supports operations through 2028. The company is advancing its multi-modality pipeline, including the introduction of the Voyager NeuroShuttle program and a collaboration with Transition Bio to develop small molecules for ALS and FTD. Upcoming milestones include anticipated clinical data for its tau-targeting programs.

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VYGR
Sep 2, 2025
VYGRConferences/Events
▲ +6.5%on this news· ran to +26% by day 3

Leveraging Genetics to Treat Neurological Diseases Citi 2025 Biopharma Back to School Conference

At the Citi 2025 Biopharma Back to School Conference, Voyager Therapeutics, Inc. (NASDAQ: VYGR) presented its strategic vision for leveraging genetics in treating neurological diseases. The company highlighted expectations for multiple clinical programs by 2026, with a focus on Alzheimer's treatments. Voyager aims to expand its gene therapy and antibody strategies while utilizing its TRACER capsid discovery platform for effective therapeutic delivery. Despite the optimism, forward-looking statements were accompanied by acknowledgment of various risks and uncertainties that could impact progress.

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VYGR
Aug 6, 2025
VYGRGeneral

Voyager Reports Second Quarter 2025 Financial and Operating Results

Voyager Therapeutics has reported its second-quarter 2025 financial results, showcasing an extended cash runway projected to last until 2028. This extension positions the company to facilitate multiple upcoming clinical data read-outs and supports the integration of its fourth pipeline asset targeting Alzheimer's disease. Switching to financial specifics, while the firm incurred a net loss of $33,382, concerns remain due to increased operating losses compared to the previous year. However, the company is optimistic about future milestones, especially with a potential $2.6 billion in development-stage milestone payments.

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VYGR
Jul 16, 2025
VYGRGeneral
▲ +6.3%on this news

Voyager Adds Fourth Wholly-Owned Alzheimer’s Disease Program to Pipeline, Complementing Existing Tau and Amyloid Assets with New APOE Approach

Voyager Therapeutics has launched a new program targeting apolipoprotein E (APOE) to treat Alzheimer's disease. This program utilizes a proprietary TRACER capsid to deliver a bifunctional payload that aims to decrease the expression of the high-risk APOE4 variant while increasing the protective APOE2 variant. The company plans to present early data from this program at a scientific meeting in 2025, further expanding its Alzheimer's pipeline.

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About Voyager Therapeutics, Inc.

Lexington, MA 141 employees voyagertherapeutics.com
Headquarters75 HAYDEN AVENUE, LEXINGTON, MA, 02421
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