Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00692705 | Positron Emission Tomography (PET) Study With [11C]AZD2995 and [11C]AZD2184, Candidate PET Ligands for β Amyloid | PHASE1 | COMPLETED | 13 | — | — | Jan 1, 2008 | Dec 1, 2008 | Jan 23, 2009 | 1 | Sweden |
| Arm | Type | Description |
|---|---|---|
| 1 | OTHER | Alzheimer's Disease (AD) patients |
| 2 | OTHER | Healthy volunteers |
| Name | Type | Description |
|---|---|---|
| Radioligand (11C)AZD2995 | DRUG | Single dose of i.v solution. 1-2 times for AD patients. Once for healthy volunteers. |
| Radioligand (11C)AZD2184 | DRUG | Single dose of i.v solution. Once for AD patients respective healthy volunteers. |
Inclusion Criteria: * Alzheimer´s Disease patients - 50-85 years- mild to moderate AD, clinical progression of AD over 12 months. * Healthy male volunteers: - Age 20-50 years, Body Mass Index: 18-30 kg/m2. * Clinically normal physical findings including normal blood pressure and pulse rate. Exclus...