Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT05818514 | A PET Study to Determine Biodistribution and Binding Characteristics of [11C]AZ14132516 in Healthy Participants | EARLY_PHASE1 | COMPLETED | 8 | — | — | Apr 27, 2023 | Jul 11, 2023 | Jul 14, 2023 | 1 | Sweden |
Standardized uptake value (SUV) is the radioactivity concentration in given region of interest normalized for injected radioactivity and body weight. Standardised uptake value ratio (SUVR) is the ratio of SUV in a given region of interest to a reference region without significant radioligand uptake
| Arm | Type | Description |
|---|---|---|
| [11C]AZ14132516 | EXPERIMENTAL | Pilot panel: up to 3 participants to complete 1 PET examination each during the course of the study Main panel: up to 6 participants to complete 2 PET examinations each during the course of the study |
| Name | Type | Description |
|---|---|---|
| [11C]AZ14132516 | DRUG | Injection of radioligand for PET examinations |
Inclusion Criteria: Informed Consent 1. Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the ICF and in the protocol. 2. Able and willing to participate in all scheduled evaluations, abide by all study restrictions, and complete a...