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efalizumab

Phase 2

Rheumatoid Arthritis | Small molecule | Immunology |XOMA Royalty Corporation|Last Updated: Jun 24, 2005

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

efalizumab · 2 trials · 2 indications

Phase 2 1Phase 1 1
NCT00034203Safety and Efficacy of a Monoclonal Antibody for Treatment of Rheumatoid Arthritis.Rheumatoid Arthritis
COMPLETED- Analytics
PHASE2COMPLETED
Safety and Efficacy of a Monoclonal Antibody for Treatment of Rheumatoid Arthritis.
Rheumatoid ArthritisUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
PurposeTREATMENT

Interventions

NameTypeDescription
efalizumabDRUG -
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Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites52

Inclusion criteria: * Clinical diagnosis of moderate to severe rheumatoid arthritis. * On stable dose of methotrexate. * 18 to 80 years of age. * Less than 275 lbs. Exclusion criteria: * Joint replacement surgery within 60 days of the start of drug dosing. * Intra-articular cortisone injections w...

Countries:United States
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Frequently asked questions about efalizumab

What is efalizumab used for?

Efalizumab is an investigational immunology drug being studied for rheumatoid arthritis and psoriatic arthritis. It is a small molecule developed by XOMA Royalty Corporation (ticker: XOMA). The drug is currently in Phase 1 clinical development, with completed trials in both indications.

What does efalizumab target?

Efalizumab is a small molecule immunology drug. The specific molecular target of efalizumab has not been disclosed in available clinical trial information. It is being investigated for its potential effects in autoimmune conditions such as rheumatoid arthritis and psoriatic arthritis.

Who makes efalizumab?

Efalizumab is developed by XOMA Royalty Corporation, which trades under the ticker XOMA. The company is conducting clinical trials to evaluate the drug's safety and efficacy in rheumatoid arthritis and psoriatic arthritis.

What phase is efalizumab in?

Efalizumab is in Phase 1 clinical development. It has completed one Phase 1 trial in psoriatic arthritis and one Phase 2 trial in rheumatoid arthritis. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is efalizumab in?

Efalizumab has been studied in two completed trials. NCT00034203 was a Phase 2 trial in rheumatoid arthritis, and NCT00051662 was a Phase 1 trial in psoriatic arthritis with 45 participants. Both trials were randomized and double-blind, though the control type was uncontrolled.

Is efalizumab the same as Raptiva?

Efalizumab is also known by the brand name Raptiva. However, the available clinical trial data for efalizumab focuses on its use in rheumatoid arthritis and psoriatic arthritis, not on other conditions. The drug is being developed by XOMA Royalty Corporation.