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SSR150106

Phase 2

Rheumatoid Arthritis | Small molecule | Immunology |Sanofi|Last Updated: Aug 8, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment79

FDA Designations

No designations recorded

Clinical trial landscape

SSR150106 · 1 trial · 1 indication

Phase 2 1
NCT00545454Activity and Safety of Oral Administration of SSR150106XB for the Reduction of Inflammation in Patients With Active Rheumatoid ArthritisRheumatoid Arthritis
COMPLETED79 Analytics
PHASE2COMPLETED
Activity and Safety of Oral Administration of SSR150106XB for the Reduction of Inflammation in Patients With Active Rheumatoid Arthritis
Rheumatoid ArthritisUnlock trial analytics

Study Endpoints

Primary Endpoints

Change from baseline in mean C-Reactive Protein level
end of the 4-week double-blind treatment period

Secondary Endpoints

C-Reactive Protein, Serum Amyloid A and Cytokine Interleukin-6 levels
at all time points measured
Improvement responder rates based on the American College of Rheumatology criteria
at all time points measured
Pain relief (change from baseline)
until day 14
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
SSR150106 QDEXPERIMENTAL90 micro grams oral solution once daily (QD)
SSR150106 OEQDEXPERIMENTAL90 micro grams oral solution once every other day (OEQD)
PlaceboPLACEBO_COMPARATORoral solution QD or OEQD

Interventions

NameTypeDescription
SSR150106DRUG -
PlacebosDRUG -
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Eligibility Criteria

Age Range18 Years to 75 Years
SexALL
Healthy VolunteersNo
Study Sites7

Inclusion Criteria: * Either treatment-naïve patients, or those who have discontinued their Rheumatoid Arthritis-directed medication due to intolerability or insufficient efficacy * At least 9 out of 68 tender joints; 6 out of 66 swollen joints; morning stiffness 45 min * C-Reactive Protein \>=1.8 ...

Countries:BulgariaCroatiaCzechiaRomaniaRussiaSlovakiaUkraine
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Frequently asked questions about SSR150106

What is SSR150106 used for?

SSR150106 is an investigational small molecule being studied for the treatment of rheumatoid arthritis. It is designed to reduce inflammation in patients with active rheumatoid arthritis. The drug is currently in clinical development and has not been approved by regulatory authorities.

What does SSR150106 target?

SSR150106 is a small molecule developed by Sanofi for the treatment of rheumatoid arthritis. Its specific molecular target has not been disclosed in available information. The drug is being investigated for its ability to reduce inflammation in patients with active rheumatoid arthritis.

Who makes SSR150106?

SSR150106 is being developed by Sanofi, a multinational pharmaceutical company listed on the stock exchange under the ticker SNY. The drug is currently in Phase 2 clinical development for the treatment of rheumatoid arthritis.

What phase is SSR150106 in?

SSR150106 is in Phase 2 clinical development. It is an investigational drug being studied for the treatment of rheumatoid arthritis. The drug has not been approved by regulatory authorities and remains in clinical trials to evaluate its safety and efficacy.

What clinical trials is SSR150106 in?

SSR150106 has been studied in one completed Phase 2 clinical trial, identified as NCT00545454. This randomized, double-blind, placebo-controlled trial enrolled 79 participants with active rheumatoid arthritis and was conducted in Bulgaria, Croatia, Czechia, Romania, Russia, Slovakia, and Ukraine.

Is SSR150106 the same as any other drug?

SSR150106 is the primary name for this investigational drug developed by Sanofi. No alternative names have been associated with this compound in available information. It is a small molecule being studied for the treatment of rheumatoid arthritis.