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Dusquetide

Phase 2

Behçet Disease | Small molecule | Other |Soligenix, Inc.|Last Updated: Aug 1, 2025

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment8
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT06386744Dusquetide for the Treatment of Behcet's DiseasePHASE2 COMPLETED 8Nov 18, 2024Jun 17, 2025Aug 1, 20251 Turkey (Türkiye)
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Study Endpoints
Primary Endpoints
Number of Oral Ulcers
4 weeks

The number of oral ulcers will be counted at baseline and each visit during the treatment period.

Number of Genital Ulcers
4 weeks

The number of genital ulcers will be counted at baseline and each visit during the treatment period.

Secondary Endpoints
Pain of Oral Ulcers
4 weeks
Pain of Genital Ulcers
4 weeks
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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
SGX945EXPERIMENTALThis is an open-label study and all participants will receive SGX945.
Interventions
NameTypeDescription
DusquetideDRUG1.5 mg/mL dusquetide administered as a 4 minute IV infusion, twice per week for 4 weeks
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Participants must have a clinical diagnosis of Behcet's Disease meeting the International Study Group criteria. * Participants must have at least two oral ulcers and/or one genital ulcer on the day of randomization. * Participants willing to follow the clinical protocol and vo...

Countries:Turkey (Türkiye)
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