Approval Probability
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Oxacillin · 1 trial · 3 indications
| Name | Type | Description |
|---|---|---|
| Linezolid | DRUG | - |
| Vancomycin | DRUG | - |
| Oxacillin | DRUG | - |
| Dicloxacillin | DRUG | - |
Inclusion Criteria: * Patients with a central indwelling catheter with signs and symptoms of infection Exclusion Criteria: * Patients with tunneled catheter which cannot be removed. * Patients with evidence of endovascular infection including endocarditis. * Patients with infection of permanent i...
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Oxacillin is a small molecule antibiotic used for bacterial infections, specifically gram-positive bacterial infections and bacteremia. It is being developed by Pfizer, Inc. for the treatment of infections related to short-term in-dwelling vascular catheters caused by gram-positive bacteria.
Oxacillin is a beta-lactam antibiotic that works by inhibiting bacterial cell wall synthesis. It targets penicillin-binding proteins, which are essential for cross-linking peptidoglycan in the bacterial cell wall, leading to cell lysis and death of susceptible gram-positive bacteria.
Oxacillin is developed by Pfizer, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. Pfizer is conducting clinical trials to evaluate the drug's efficacy in treating bacterial infections.
Oxacillin is in Phase 3 clinical development. It is an investigational drug for bacterial infections and has not been approved by the FDA. The Phase 3 trial has been completed, with results expected to inform potential regulatory submissions.
Oxacillin has one completed Phase 3 clinical trial, NCT00037050, titled 'Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteria.' The trial enrolled 739 participants aged 13 years and older, including both males and females, and was not blinded or controlled.
Oxacillin is a distinct antibiotic in the penicillin class, specifically a beta-lactamase-resistant penicillin. It is not the same as other penicillins like amoxicillin or methicillin, though it shares a similar mechanism of action. Its unique structure provides activity against certain penicillin-resistant staphylococci.