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Interleukin-3

Phase 1

HIV Infections | Small molecule | Hematology |Novartis AG|Last Updated: Jun 24, 2005

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

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Clinical trial landscape

Interleukin-3 · 1 trial · 2 indications

Phase 1 1
NCT00002258A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With CytopeniaHIV Infections
COMPLETED- Analytics
PHASE1COMPLETED
A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia
HIV InfectionsUnlock trial analytics

Study Design & Arms

MaskingNONE
PurposeTREATMENT

Interventions

NameTypeDescription
Interleukin-3DRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria Patients must have: * HIV seropositivity by Western blot. * Advanced ARC or AIDS as defined by CDC. * Cytopenia defined as total peripheral leukocyte count of \< 3,000 cells/mm3 or platelet count of \< 100,000 cells/mm3 or serum hemoglobin \< 10 g/dl. * Anticipated life expectan...

Countries:United States
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Frequently asked questions about Interleukin-3

What is Interleukin-3 used for in HIV Infections?

Interleukin-3 is an investigational small molecule being studied for the treatment of HIV infections, specifically in patients with cytopenia. It was evaluated in a Phase 1 clinical trial to assess its safety, tolerance, and biological effects in HIV-infected patients with cytopenia. The drug is still in clinical development and is not approved.

Who makes Interleukin-3?

Interleukin-3 is being developed by Novartis AG, a multinational pharmaceutical company traded on the New York Stock Exchange under the ticker symbol NVS. The company conducted a Phase 1 clinical trial of the drug in the United States for HIV infections with cytopenia.

What phase is Interleukin-3 in?

Interleukin-3 is in Phase 1 clinical development. A single Phase 1, open-label trial has been completed to evaluate the safety, tolerance, and biological effects of the drug in HIV-infected patients with cytopenia. The drug remains investigational and has not received FDA approval.

What clinical trials is Interleukin-3 in?

Interleukin-3 has one completed clinical trial, identified as NCT00002258. This Phase 1, open-label trial evaluated the safety, tolerance, and biological effects of SDZ ILE-964 (recombinant human interleukin-3) in HIV-infected patients with cytopenia. The trial was conducted in the United States and enrolled adults aged 18 years and older.

What does Interleukin-3 target?

Interleukin-3 is a recombinant human interleukin-3, which is a cytokine that stimulates the production and differentiation of blood cells. In the context of HIV infections, it is being studied for its potential to address cytopenia, a condition characterized by low blood cell counts.