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nexium

Phase 3

Type 2 Diabetes | Small molecule | Metabolic |Novo Nordisk A/S|Last Updated: Sep 3, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment41

FDA Designations

No designations recorded

Clinical trial landscape

nexium · 1 trial · 1 indication

Phase 3 1
NCT00699426The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 DiabetesType 2 Diabetes
COMPLETED41 Analytics
PHASE3COMPLETED
The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes
Type 2 DiabetesUnlock trial analytics

Study Endpoints

Primary Endpoints

insulin secretion
1 year

Secondary Endpoints

blood pressure
1 year
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelFACTORIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Nexium + YoghurtACTIVE_COMPARATOR -
Nexium + PlaceboPLACEBO_COMPARATOR -
Placebo+ YoghurtPLACEBO_COMPARATOR -
placebo+placeboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
nexiumDRUG40 mg once daily is tested together with Yoghurt
YoghurtDIETARY_SUPPLEMENTYoghurt
placebo+placeboDRUGplacebo and placebo are tested.
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Eligibility Criteria

Age Range40 Years to 70 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Type 2 diabetes (WHO criteria) treated with metformin and/or sulfonylureas or diet * Males and females between 40 and 70 years * HbA1c between 6,0-10,0 * Diabetes duration \> 1 year Exclusion Criteria: * Kidney disease (s-creatinine above the upper limit of normal range). * ...

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Frequently asked questions about nexium

What is Nexium used for in Type 2 Diabetes?

Nexium is being studied for its effect on insulin secretion and cardiovascular risk factors in patients with Type 2 Diabetes. It is an investigational small molecule in Phase 3 clinical development for this indication. The drug is being evaluated in a randomized, double-blind, placebo-controlled trial.

Who makes Nexium?

Nexium is being developed by Novo Nordisk A/S, a biopharmaceutical company listed on the stock exchange under the ticker NVO. The company is conducting clinical research to evaluate the drug's potential in treating Type 2 Diabetes.

What phase is Nexium in?

Nexium is in Phase 3 clinical development for Type 2 Diabetes. It is an investigational drug, meaning it has not been approved for this use and is still undergoing clinical trials to assess its safety and efficacy.

What clinical trials is Nexium in?

Nexium is being studied in a Phase 3 clinical trial with the identifier NCT00699426. The trial is titled "The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes" and has been completed. The study enrolled 41 participants aged 40 years and older.

Is Nexium the same as esomeprazole?

Nexium is the brand name for esomeprazole, a proton pump inhibitor. In the context of this clinical trial, Nexium is being investigated for its potential effects on insulin secretion and cardiovascular risk factors in patients with Type 2 Diabetes.