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NewAmsterdam Pharma Company N.V.

NAMS
OvervaluedPharma · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$21.26
▼ -0.87 · -3.93%

Financials

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52W LOW $20.9152W HIGH $42.20
Volume
1.67 M
Value Traded
25.20 M
Short % Float
20.54%
-8.36%Week
-6.71%1 Month
-39.71%3 Month
-38.84%6 Month
+265.36%5 Year
+229.67%All Time

Cash Data

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  • Burn Trend
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Key Stats

Market Cap
2.54 B
EPS (TTM)
-2.17
P/E Ratio
-
Ent. Value
1.86 B
Total Shares
119.49 M
Float Shares
76.26 M
Insiders
36.21%
Institutions
69.25%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 data readout
obicetrapib
cardiovascular disease
Phase 3Small MoleculesCardiovascular System
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PoA blends historical approval base rates, trial design score and FDA review track record.

NAMS Catalyst Timeline

Dated clinical, regulatory and corporate events for NewAmsterdam Pharma Company N.V.

Catalyst Timeline

Dated clinical, regulatory & corporate events for NewAmsterdam Pharma Company N.V.

264Total events
12Upcoming
69Tier-1 (high impact)
2022 to 2027Coverage

Upcoming catalysts 2

T2Product Launch
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ObicetrapibFiled
T1Interim Analysis
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ObicetrapibFiled

Event history 50

●Grant / FundingCorporate
Compensation Committee approved inducement stock option grant of 71,800 shares to 7 new hires
●Equity OfferingCorporate
Inducement stock options granted to 7 new hires (71,800 shares)
▲First Patient DosedObicetrapibFiledTrial
First participant dosed in Phase 2b SPINOZA trial of obicetrapib in preclinical Alzheimer's disease
preclinical Alzheimer's diseasesource ↗
▲EU ApprovalObicetrapibFiledEx-US Regulatory
Comisión Europea aprueba Evlarco (combinación fija obicetrapib 10 mg + ezetimiba 10 mg)
hipercolesterolemia primaria (HeFH y dislipidemia no familiar o mixta)source ↗
▲EU ApprovalUbesloApprovedEx-US Regulatory
European Commission grants marketing authorization for Ubeslo (obicetrapib monotherapy)
hypercholesterolemia (heterozygous familial hypercholesterolemia and non-familial/mixed dyslipidemia)source ↗
▲EU ApprovalEvlarcoApprovedEx-US Regulatory
European Commission grants marketing authorization for Evlarco (fixed-dose obicetrapib + ezetimibe)
hypercholesterolemia (heterozygous familial hypercholesterolemia and non-familial/mixed dyslipidemia)source ↗
▲EU ApprovalUbesloApprovedEx-US Regulatory
EC grants marketing authorization for Ubeslo (obicetrapib monotherapy)
primary hypercholesterolaemia, both heterozygous familial (HeFH) and non-familial or mixed dyslipidaemiasource ↗
▲EU ApprovalEvlarcoApprovedEx-US Regulatory
EC grants marketing authorization for Evlarco (obicetrapib plus ezetimibe FDC)
primary hypercholesterolaemia, both heterozygous familial (HeFH) and non-familial or mixed dyslipidaemiasource ↗
◆Poster PresentationObicetrapibFiledPresentation
Pooled On-Treatment Lipid-Lowering Efficacy of the CETP Inhibitor Obicetrapib in Phase III Trials
elevated LDL-Csource ↗
◆Poster PresentationObicetrapibFiledPresentation
Determinants of Short Term Lp(a) Variability in Phase 3 Obicetrapib Trials
elevated LDL-Csource ↗
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Past FDA Catalysts and PDUFA Decisions

How NAMS actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-06-12Obicetrapib Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

C51 / 100
Pipeline Score
$1.2B
Pipeline Value
Overvalued
Valuation Signal
2
Drugs Scored
0.4x
rNPV / MCap
Top 16%
Small Cap
(rank 106 of 658)
Percentile Rank
NewAmsterdam Pharma Company N.V. carries a moderate pipeline score (51/100), with $1.8B risk-adjusted pipeline value, led by Obicetrapib in Atherosclerotic Cardiovascular Disease (Phase 3), across $66B in total addressable markets.
Showing 1 of 2 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Obicetrapib Small moleculeNCT05202509Atherosclerotic Cardiovascular DiseasePhase 3 ACTIVE NOT_RECRUITING 9,541Nov 1, 2026
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Clinical Trial Results

Readouts, endpoints and source filings for every NAMS program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Obicetrapib cardiometabolic diseases2026-03-02initial 12 month rate is tracking in line with the overall rate observed in the Phase 3 BROADWAY trialRead MoreInvestor Presentation as ofRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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InsiderSideSharesPriceValueDate
Kastelein Johannes Jacob PieterDirector, Officer (Chief Scientific Officer)Option 50,246 119,548 held$0.00 09/30/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Frazier Life Sciences Management, L.P. 13.3 % (-5 %) 613.03 M 18.09 M 6.76% ( 1.15 M)
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NAMS Institutional Ownership Trends

Options Data

Option Volume

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Call OI
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Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-16
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

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Competitive positioning

How NAMS ranks across every disease it competes in

Competitive Position is a premium feature
See how NAMS ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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NAMS News

NAMS
Oct 2, 2026
NAMSGeneral

NewAmsterdam Pharma Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

NewAmsterdam Pharma has announced the approval of inducement share options and restricted stock units for new non-executive hires. A total of 71,800 share options and 17,745 restricted stock units were granted under the 2024 Inducement Plan. These grants aim to incentivize new employees and align their interests with the company's growth.

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NAMS
Sep 29, 2026
NAMSPhases

NewAmsterdam Pharma Doses First Participant in Phase 2b SPINOZA Trial Evaluating Obicetrapib in Preclinical Alzheimer’s Disease

NewAmsterdam Pharma has initiated the SPINOZA trial, dosing its first participant to evaluate obicetrapib in individuals with preclinical Alzheimer's disease. This Phase 2b trial aims to assess the drug's impact on biomarkers associated with Alzheimer's pathology. The study will involve approximately 400 participants and is designed to explore the efficacy and safety of obicetrapib before clinical symptoms manifest.

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NAMS
Sep 23, 2026
NAMSFDA Updates

Menarini Group y NewAmsterdam Pharma reciben la aprobación de la Comisión Europea para Ubeslo® y Evlarco®

Menarini Group and NewAmsterdam Pharma have received European Commission approval for Ubeslo® and Evlarco®, marking the first global regulatory approval for obicetrapib. This approval is based on phase 3 trials showing significant reductions in LDL-C levels. The drugs offer new treatment options for patients with primary hypercholesterolemia.

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NAMS
Sep 21, 2026
NAMSFDA Updates

Menarini Group und NewAmsterdam Pharma erhalten von der Europäischen Kommission die Zulassung für Ubeslo® (Obicetrapib als Monotherapie) und Evlarco® (Fixkombination aus Obicetrapib und Ezetimib)

NewAmsterdam Pharma and Menarini Group have received approval from the European Commission for Ubeslo (Obicetrapib as monotherapy) and Evlarco (combination of Obicetrapib and Ezetimib). This marks the first global approval of Obicetrapib, providing a new treatment option for patients with primary hypercholesterolemia. The approval is based on positive results from Phase 3 studies demonstrating significant LDL-C reductions.

Read more →
NAMS
Sep 21, 2026
NAMSFDA Updates

Menarini Group and NewAmsterdam Pharma Receive European Commission Approval for Ubeslo® (Obicetrapib Monotherapy) and Evlarco® (Obicetrapib Plus Ezetimibe Fixed-Dose Combination)

NewAmsterdam Pharma and Menarini Group have received European Commission approval for Ubeslo (obicetrapib monotherapy) and Evlarco (obicetrapib plus ezetimibe). This marks the first global regulatory approval for obicetrapib, supported by positive results from Phase 3 trials showing significant reductions in LDL-C levels. The approval aims to provide new treatment options for patients struggling with elevated LDL-C.

Read more →
NAMS
Sep 21, 2026
NAMSFDA Updates

NewAmsterdam Pharma and Menarini Group Receive European Commission Approval for Ubeslo® (Obicetrapib Monotherapy) and Evlarco® (Obicetrapib Plus Ezetimibe Fixed-Dose Combination)

NewAmsterdam Pharma and Menarini Group have received European Commission approval for Ubeslo® and Evlarco®, marking the first global regulatory approval for obicetrapib. This approval is supported by Phase 3 trials showing significant reductions in LDL-C levels. The companies aim to provide new treatment options for patients struggling with elevated LDL-C levels.

Read more →
NAMS
Sep 2, 2026
NAMSConferences/Events

NewAmsterdam Pharma to Participate at Upcoming Investor Conferences in September

NewAmsterdam Pharma will participate in two investor conferences in September 2026, showcasing its commitment to addressing cardiovascular disease. CEO Michael Davidson and EVP Matthew Philippe will present at the Wells Fargo Healthcare Conference, while CFO Ian Somaiya will join the Cantor Global Healthcare Conference. Live webcasts of the events will be available on their website.

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NAMS
Aug 26, 2026
NAMSConferences/Events

NewAmsterdam Pharma Announces Upcoming Presentations at the European Society of Cardiology (ESC) Congress 2026

NewAmsterdam Pharma will present findings from its obicetrapib development program at the ESC Congress 2026 in Munich. The presentations will cover various aspects of obicetrapib's efficacy and safety in lowering LDL cholesterol. The company aims to address unmet needs in cardiovascular disease treatment with this novel therapy. The Phase 3 PREVAIL trial has successfully enrolled over 9,500 patients.

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NAMS
Aug 5, 2026
NAMSGeneral

NewAmsterdam Pharma Provides Corporate Update and Reports Second Quarter Financial Results

NewAmsterdam Pharma reported a positive opinion from the CHMP recommending marketing authorization for obicetrapib and its combination with ezetimibe. The company announced a strong cash position of $678.3 million and highlighted upcoming clinical milestones, including topline data from the RUBENS Phase 3 trial expected by the end of 2026. However, the company also reported a net loss of $64.1 million for the quarter, reflecting increased R&D expenses.

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NAMS
Jul 29, 2026
NAMSConferences/Events

NewAmsterdam Pharma to Host Investor Day on August 5, 2026

NewAmsterdam Pharma will host an Investor Day on August 5, 2026, in New York City. The event will feature key executives and provide insights into the company's developments, particularly regarding obicetrapib, a novel treatment for cardiovascular disease. A live webcast will be available for those unable to attend in person.

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NAMS
Jul 26, 2026
NAMSFDA Updates

NewAmsterdam Pharma und die Menarini Group erhalten positive Stellungnahme des CHMP mit der Empfehlung zur Erteilung einer Zulassung für Ubeslo® (Obicetrapib-Monotherapie) und Evlarco® (Festsatzkombination aus Obicetrapib und Ezetimib)

NewAmsterdam Pharma and Menarini Group received a positive CHMP recommendation for the approval of Ubeslo® (Obicetrapib monotherapy) and Evlarco® (combination with Ezetimib). This recommendation is based on favorable Phase 3 study results showing significant LDL-C reductions. The final decision from the European Commission is expected in the second half of 2026.

Read more →
NAMS
Jul 24, 2026
NAMSFDA Updates

NewAmsterdam Pharma y Menarini Group reciben una opinión positiva del CHMP sobre Ubeslo®

NewAmsterdam Pharma and Menarini Group received a positive opinion from the CHMP recommending the marketing authorization of Ubeslo® and Evlarco®. This recommendation is based on favorable results from phase 3 trials, indicating significant LDL-C reduction. The final decision from the European Commission is expected in the second half of 2026.

Read more →
NAMS
Jul 24, 2026
NAMSFDA Updates

NewAmsterdam Pharma and Menarini Group Receive Positive CHMP Opinion Recommending Marketing Authorization for Ubeslo® (Obicetrapib Monotherapy) and Evlarco® (Obicetrapib Plus Ezetimibe Fixed-Dose Combination)

NewAmsterdam Pharma and Menarini Group received a positive opinion from the CHMP recommending marketing authorization for obicetrapib monotherapy and its fixed-dose combination with ezetimibe. This recommendation is based on positive results from Phase 3 trials, indicating significant LDL-C reductions. The European Commission's final decision is anticipated in the second half of 2026.

Read more →
NAMS
Jul 1, 2026
NAMSConferences/Events

NewAmsterdam Pharma Announces Upcoming Presentations at the Alzheimer's Association International Conference (AAIC) 2026

NewAmsterdam Pharma announced it will present data on obicetrapib at the Alzheimer's Association International Conference (AAIC) 2026. The presentations will focus on the drug's potential in preventing early Alzheimer's disease, supported by findings from the BROADWAY trial. The company aims to address unmet needs in cardiovascular disease management with this novel therapy.

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NAMS
Jun 3, 2026
NAMSConferences/Events

NewAmsterdam Pharma Announces Upcoming Presentations at the National Lipid Association (NLA) 2026 Scientific Sessions

NewAmsterdam Pharma announced its upcoming presentations at the National Lipid Association 2026 Scientific Sessions, focusing on obicetrapib, a novel oral therapy for hypercholesterolemia. The presentations will cover various aspects of obicetrapib, including safety analyses and its effects on LDL cholesterol. The event will take place from June 11 to 14, 2026, in Chicago.

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NAMS
May 28, 2026
NAMSConferences/Events

NewAmsterdam Pharma to Participate at Upcoming Investor Conferences in June

NewAmsterdam Pharma will participate in two major investor conferences in June 2026. CEO Michael Davidson and EVP Matthew Philippe will engage in fireside chats at the Jefferies Global Healthcare Conference and the Goldman Sachs Global Healthcare Conference. These events will provide insights into the company's developments in LDL-lowering therapies for cardiovascular disease.

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NAMS
May 11, 2026
NAMSConferences/Events

NewAmsterdam Pharma to Participate at Upcoming Investor Conferences in May

NewAmsterdam Pharma will participate in two upcoming investor conferences in May 2026. The BofA Securities Health Care Conference will take place on May 12, followed by the RBCCM Global Healthcare Conference on May 20. Key executives will engage in fireside chats, discussing the company's innovative approaches to treating cardiovascular disease.

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About NewAmsterdam Pharma Company N.V.

Narrden, P7 100 employees newamsterdampharma.com
HeadquartersGOOIMEER 2-35, NARRDEN, P7, 1411 DC
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