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obicetrapib + ezetimibe daily

Phase 3

Lipidemia | Small molecule | Metabolic |NewAmsterdam Pharma Company N.V.|Last Updated: Mar 9, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials2
Total Enrollment600
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07219602A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic SyndromePHASE3 RECRUITING 300Dec 1, 2025Jun 1, 2028Mar 9, 2026 -
NCT06305559A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary PlaquePHASE3 RECRUITING 300May 1, 2024Mar 1, 2027Jun 14, 2025 -
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Study Design & Arms
Interventions
NameTypeDescription
obicetrapib 10 mg + ezetimibe 10 mg FDC dailyDRUGFDC
Obicetrapib 10 mgDRUGmonotherapy
PlaceboOTHERplacebo on top of guideline-recommended lipid modifying therapy
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Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT06305559studyFirstPostDate: changed
LOWMay 24, 2026NCT07219602studyFirstPostDate: changed