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MK0677

Phase 2

Alzheimer's Disease | Small molecule | Neurology |Merck & Company, Inc.|Last Updated: Jul 24, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment512

FDA Designations

No designations recorded

Clinical trial landscape

MK0677 · 1 trial · 1 indication

Phase 2 1
NCT00074529Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)Alzheimer's Disease
COMPLETED512 Analytics
PHASE2COMPLETED
Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)
Alzheimer's DiseaseUnlock trial analytics

Study Endpoints

Primary Endpoints

Cognitive function over 12 month period; safety and tolerability
over 12 month period

Secondary Endpoints

AD symptoms over a 6 month and 12 month period measured by the CIBIC + and the ADAS-Cog.
over a 6 month and 12 month period
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
PurposeTREATMENT

Interventions

NameTypeDescription
MK0677DRUG -
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Eligibility Criteria

Age Range50 Years to N/A
SexALL
Healthy VolunteersNo

* Patients must have probable Alzheimer's disease of mild or moderate severity. * A brain scan and laboratory results must be consistent with Alzheimer's disease. * The patient must be otherwise medically healthy.

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Frequently asked questions about MK0677

What is MK0677 used for?

MK0677 is an investigational small molecule being studied for the treatment of Alzheimer's Disease. It is in Phase 2 clinical development and has not been approved by regulatory authorities. The drug is being developed by Merck & Company, Inc. (MRK).

What does MK0677 target?

The specific molecular target of MK0677 is not disclosed in the available information. The drug is a small molecule being investigated for its potential effects in Alzheimer's Disease, but its mechanism of action has not been publicly detailed.

Who makes MK0677?

MK0677 is being developed by Merck & Company, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol MRK. The drug is currently in Phase 2 clinical trials for Alzheimer's Disease.

What phase is MK0677 in?

MK0677 is in Phase 2 clinical development. It is an investigational drug for Alzheimer's Disease and has not been approved by the FDA or other regulatory agencies. One Phase 2 trial has been completed, involving 512 participants.

What clinical trials is MK0677 in?

MK0677 has one completed Phase 2 clinical trial registered as NCT00074529, titled 'Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)'. The trial enrolled 512 participants aged 50 years and older with Alzheimer's Disease. It was a randomized, double-blind, uncontrolled study.

Is MK0677 the same as any other drug?

No alternative names for MK0677 have been identified in the available information. The drug is referred to solely as MK0677 in clinical trial records and development documentation.