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L-697,661

Phase 1

HIV Infections | Small molecule | Infectious Disease |Merck & Company, Inc.|Last Updated: Jul 30, 2008

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment27
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00000628A Pharmacokinetic Study of L-697,661 Alone and in Combination With ZidovudinePHASE1 COMPLETED 27 - -Jul 30, 20085 United States
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Study Design & Arms
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
L-697,661DRUG -
ZidovudineDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria Patients must have: * HIV infection. Prior Medication: Included: * Patients in Part 1 must have received no previous zidovudine (AZT) or a stable dose of at least 500 mg/day without evidence of toxicity. * Patients in Part 2 must have received no previous AZT or = or \> 300 mg...

Countries:United States
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