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Efavirenz

Phase 2

HIV Infections | Small molecule | Infectious Disease |Merck & Company, Inc.|Last Updated: Jun 24, 2005

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials2
Total Enrollment120
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00002225A Study of Efavirenz in Combination With Stavudine and DidanosinePHASE2 COMPLETED 60 - -Jun 24, 20055 United States
NCT00002227A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV DrugsPHASE2 COMPLETED 60 - -Jun 24, 20058 United States
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Study Design & Arms
PurposeTREATMENT
Interventions
NameTypeDescription
EfavirenzDRUG -
StavudineDRUG -
DidanosineDRUG -
LamivudineDRUG -
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Eligibility Criteria
Age Range13 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria Patients must have: * Documented HIV infection with plasma HIV-RNA greater than or equal to 10,000 copies/ml. * A life expectancy of at least 12 months. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Current bilat...

Countries:United States
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