Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT07142954 | Epidemiology and Biomarker Study in Alzheimer's Disease | PHASE3 | RECRUITING | 3,400 | — | — | Aug 25, 2025 | Jul 1, 2033 | May 14, 2026 | 4 | United States, Japan |
Cognitive composite may consist of International Daily Symbol Substitution Test-Medicines (iDSSTm ), International Shopping List Test (ISLT), Continuous Paired Associate Learning Test (CPAL). Time to cognitive worsening is defined as a change in cognitive composite score or any of the individual composite components, from baseline at 2 consecutive visits.
| Arm | Type | Description |
|---|---|---|
| Elevated Plasma P-tau217 Levels | OTHER | Participants with known elevated plasma P-tau217 levels who are cognitively unimpaired at baseline per self-report. |
| Not-Elevated P-tau217 Levels | OTHER | Participants with known not-elevated plasma P-tau217 levels who are cognitively unimpaired at baseline per self-report. |
| Name | Type | Description |
|---|---|---|
| P-tau217 Test | OTHER | A plasma test measuring phosphorylated tau at Position 217 (P-tau217). |
Inclusion Criteria: * The participant must self-report unimpaired cognition. * The participant must have adequate literacy, vision, and hearing for neuropsychological assessments at the time of screening. Exclusion Criteria: * Have seen a doctor about memory concerns. * Have a history or diagnosi...