Recent Updates
Recently added Catalysts

Tenofovir disoproxil

Phase 3

HIV Infections | Small molecule | Infectious Disease |Gilead Sciences, Inc.|Last Updated: Jun 24, 2005

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
Double-BlindUNCONTROLLEDBiomarker
Total Trials2
Total Enrollment775
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00002450Safety and Effectiveness of Tenofovir Disoproxil Fumarate (Tenofovir DF) Plus Other Anti-HIV Drugs in HIV-Infected PatientsPHASE3 COMPLETED 600 - -Jun 24, 200561 United States, Puerto Rico
NCT00002415Safety and Effectiveness of Adding PMPA Prodrug to an Anti-HIV Drug Combination to Treat HIV-Infected PatientsPHASE2 COMPLETED 175 - -Jun 24, 200524 United States
Unlock Drug Trial Details
Study Design & Arms
MaskingDOUBLE
PurposeTREATMENT
Interventions
NameTypeDescription
Tenofovir disoproxil fumarateDRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 65 Years
SexALL
Healthy VolunteersNo
Study Sites61

Inclusion Criteria Patients may be eligible for this study if they: * Are HIV-positive. * Have been on stable anti-HIV therapy for at least 8 weeks with no more than 4 anti-HIV drugs at the time of study entry. * Have a viral load (level of HIV in the blood) between 400 and 10,000 copies/ml. * Hav...

Countries:United StatesPuerto Rico
Unlock Eligibility Criteria