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Levocarnitine

Phase 2

HIV Infections | Small molecule | Infectious Disease |Gilead Sciences, Inc.|Last Updated: Jun 24, 2005

Success Probability

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Market & Valuation

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Trial Design

Double-BlindUNCONTROLLED
Total Trials2
Total Enrollment220

FDA Designations

No designations recorded

Clinical trial landscape

Levocarnitine · 2 trials · 1 indication

Phase 2 2
NCT00002184A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected PatientHIV Infections
COMPLETED120 Analytics
NCT00002379The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV DrugsHIV Infections
COMPLETED100 Analytics
PHASE2COMPLETED
A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient
HIV InfectionsUnlock trial analytics
PHASE2COMPLETED
The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
HIV InfectionsUnlock trial analytics

Study Design & Arms

MaskingDOUBLE
PurposeTREATMENT

Interventions

NameTypeDescription
Nelfinavir mesylateDRUG -
LevocarnitineDRUG -
Adefovir dipivoxilDRUG -
SaquinavirDRUG -
LamivudineDRUG -
StavudineDRUG -
ZidovudineDRUG -
Indinavir sulfateDRUG -
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Eligibility Criteria

Age Range16 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites15

Inclusion Criteria Patients must have: * Laboratory diagnosis of HIV infection (positive HIV antibody test confirmed by Western blot, p24 antigen assay, HIV-1 RNA, or HIV-1 culture). * An HIV-1 RNA plasma titer \>= 5000 copies/ml within 14-21 days prior to the baseline visit. * CD4 cell count \>= ...

Countries:United StatesPuerto Rico
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