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Basal insulin

Phase 1

Type 2 Diabetes | Small molecule | Metabolic |DexCom, Inc.|Last Updated: Jul 2, 2026

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment45

FDA Designations

No designations recorded

Clinical trial landscape

Basal insulin · 1 trial · 1 indication

Phase 1 1
NCT07681375Evaluation of Basal Insulin Initialization and Titration in People With Type 2 Diabetes Wearing a Dexcom G6 SensorType 2 Diabetes
ACTIVE NOT_RECRUITING45 Analytics
PHASE1ACTIVE NOT_RECRUITING
Evaluation of Basal Insulin Initialization and Titration in People With Type 2 Diabetes Wearing a Dexcom G6 Sensor
Type 2 DiabetesUnlock trial analytics

Study Endpoints

Primary Endpoints

Measurement of participant safety while using the DexBasal Study System
Day 10 up to 8 weeks

Subject safety measured by the number of Severe Adverse Events (SAEs)

Measurement of system recommended dose
Day 10 up to 8 weeks

System functionality measured by the generation of a recommended dose.

Frequency of Physician approval of Dexbasal Study system's daily dose recommendation
Day 10 up to 8 weeks

System functionality measured by the physician review and physician approval of daily dose recommendations in Phase 2.

Subject reported insulin dose
Day 10 up to 8 weeks

System functionality measured by the subject-reported basal insulin dose injections.

Evaluation of the CGM Metrics based on average glucose
Baseline through end of study, an average of 96 days

-Measure of Average glucose (mg/dL)

Evaluation of the CGM Metrics using coefficient variation (CV)
Baseline through end of study, an average of 96 days

\- Measure of CV (%)

Evaluation of the CGM Metrics for time in range (TIR)
Baseline through end of study, an average of 96 days

\- Measure of TIR (70-180 mg/dL) (%)

Evaluation of the CGM Metrics of time spent very low
Baseline through end of study, an average of 96 days

\- Measure of Time spent very low (\<54 mg/dL) (%)

Evaluation of the CGM Metrics of time spent low
Baseline through end of study, an average of 96 days

\- Measure of Time spent low (54-69 mg/dL) (%)

Evaluation of the CGM Metrics of time spent below 70 mg/dL
Baseline through end of study, an average of 96 days

\- Measure of Time spent low (\<70 mg/dL) (%)

Evaluation of the CGM Metrics of time spent high
Baseline through end of study, an average of 96 days

\- Measure of Time spent high (\>180 mg/dL) (%)

Evaluation of the CGM Metrics of time spent very high
Baseline through end of study, an average of 96 days

\- Measure of Time spent very high (\>250 mg/dL) (%)

Measure of glycemic control
Baseline through end of study, an average of 96 days

Fasting Glucose

Secondary Endpoints

Gain understanding and perspective from study subjects with questionnaires
End of study, on average Day 96
Gain understanding and perspective from study subjects through status questionnaire
Baseline
Gain understanding and perspective from study subjects through Relationship Scale
Baseline through end of study, an average of 96 days
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeDEVICE_FEASIBILITY

Treatment Arms

ArmTypeDescription
DexbasalOTHERSubjects initiating basal insulin therapy or on basal insulin therapy maintenance and benefit from transitioning to a study-specific type of basal insulin within 72 hours of Phase 1.

Interventions

NameTypeDescription
Basal insulinDRUGdaily basal insulin dose
Dexcom Continuous Glucose Monitoring (CGM)DEVICEDexcom Continuous Glucose Monitoring (CGM) Sensor
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: Patients with a diagnosis of Type 2 diabetes (T2D) mellitus * Ages equal or greater 18 years ("age" determined at the time of the Screening Visit) * Bodyweight between 30-450 kg * Comfortable with and willing to administer basal insulin injections, once a day, for approximately ...

Countries:United States
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Recent Changes (Last 90 Days)

LOWJul 2, 2026NCT07681375NEW_TRIAL: changed
LOWJul 2, 2026NCT07681375NEW_TRIAL: changed

Frequently asked questions about Basal insulin

What is Basal insulin used for in Type 2 Diabetes?

Basal insulin is being studied for use in people with Type 2 Diabetes. It is intended to help manage blood sugar levels by providing a steady background level of insulin. The drug is currently in Phase 1 clinical development and is being evaluated in a clinical trial in the United States.

Who makes Basal insulin?

Basal insulin is being developed by DexCom, Inc., a company traded on the NASDAQ under the ticker DXCM. DexCom is conducting clinical research on this drug for the treatment of Type 2 Diabetes.

What phase is Basal insulin in?

Basal insulin is in Phase 1 clinical development. It is an investigational drug and has not yet been approved by regulatory authorities. The drug is currently being studied in an active clinical trial that is not yet recruiting participants.

What clinical trials is Basal insulin in?

Basal insulin is being evaluated in a Phase 1 clinical trial with the identifier NCT07681375. The trial is titled 'Evaluation of Basal Insulin Initialization and Titration in People With Type 2 Diabetes Wearing a Dexcom G6 Sensor' and is being conducted in the United States with an enrollment of 45 participants.

Is Basal insulin the same as Dexcom G6?

No, Basal insulin is not the same as Dexcom G6. Basal insulin is an investigational drug being developed by DexCom, Inc. for Type 2 Diabetes. Dexcom G6 is a continuous glucose monitoring system, which is a device used to track glucose levels. The clinical trial for Basal insulin involves participants wearing a Dexcom G6 sensor.